PIMA544505

Phospho-STAT3 (Ser727) Recombinant Rabbit Monoclonal Antibody (BLR160J), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544505-Each-of-1 In Stock ₹ 33,881.76

PIMA544505 - Each of 1

₹ 33,881.76

In Stock

Quantity

1

Base Price: ₹ 33,881.76

GST (18%): ₹ 6,098.717

Total Price: ₹ 39,980.477

Antigen

Phospho-STAT3 (Ser727)

Classification

Recombinant Monoclonal

Concentration

10 μg/mL

Formulation

BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.

P40763

Gene Symbols

STAT3

Immunogen

Surrounding Serine 727

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunoprecipitation, Western Blot

Clone

BLR160J

Conjugate

Unconjugated

Gene

STAT3

Gene Alias

1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

6774

Content And Storage

2-8°C

Form

Liquid

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Description

  • STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
  • Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
  • STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
  • Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
  • In humans, the STAT3 gene is located on the q arm of chromosome 17
  • STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
  • The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
  • STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
  • The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
  • Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
  • Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA544505

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Antigen:
Phospho-STAT3 (Ser727)

Classification:
Recombinant Monoclonal

Concentration:
10 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
P40763

Gene Symbols:
STAT3

Immunogen:
Surrounding Serine 727

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
BLR160J

Conjugate:
Unconjugated

Gene:
STAT3

Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
6774

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544507

--


Antigen:
Arginase 1

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
Q61176

Gene Symbols:
ARG1

Immunogen:
Residues 1-322 (Fl)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR161J

Conjugate:
Unconjugated

Gene:
ARG1

Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
11846

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544508

--


Antigen:
Arginase 1

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
Q61176

Gene Symbols:
ARG1

Immunogen:
Residues 1-322 (Fl)

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR161J

Conjugate:
Unconjugated

Gene:
ARG1

Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
11846

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544510

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Antigen:
CD16

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2

Gene Accession No.:
O75015, P08637

Gene Symbols:
FCGR3A, FCGR3B

Immunogen:
Between 204 And 254 (C-Term)

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
BLR162J

Conjugate:
Unconjugated

Gene:
FCGR3B

Gene Alias:
4833442P21Rik; CD16; CD16-2; CD16A; CD16a antigen; CD16b; CD32; CD32 receptor 2; CDw32; cytolytic trigger molecule G7; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor IIIb; Fc gamma RIIIa; Fc gammaRIV; Fc receptor, IgG, low affinity III; Fc receptor, IgG, low affinity IV; Fc receptor-like 3; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RII-b; Fc-gamma RII-c; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; fc-gamma RIIIb; fc-gamma RIII-beta; Fc-gamma-RIIb; Fc-gamma-RIIc; FcgammaRIII; FcgammaRIII a.1; FcgammaRIII a.2; FcgammaRIII a.3; FcgammaRIIIA; FcgammaRIV; FCGR2; FCGR2A; FCGR2B; FCGR2C; FCGR3; Fcgr3a; FCGR3B; Fcgr4; FCGRIII; FcgRIV; FcR-10; FcRII-b; FcRII-c; FcRIII; FCRIIIA; FCRIIIb; Fcrl3; IGFR3; IgG Fc gamma receptor III; igG Fc receptor III; IgG Fc receptor III-1; igG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; LOC100911825; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-like; Low affinity immunoglobulin gamma Fc region receptor IV; neutrophil-specific antigen NA; RP11-5K23.1; transmembrane receptor FcgammaRIII-X

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
2214, 2215

Content And Storage:
2-8°C

Form:
Liquid