PIMA544541

iNOS Recombinant Rabbit Monoclonal Antibody (BLR181J), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA544541-Each-of-1 In Stock ₹ 40,726.56

PIMA544541 - Each of 1

₹ 40,726.56

In Stock

Quantity

1

Base Price: ₹ 40,726.56

GST (18%): ₹ 7,330.781

Total Price: ₹ 48,057.341

Antigen

iNOS

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

BBS with 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.

P29477

Gene Symbols

Nos2

Immunogen

Between 1094 And 1144 (C-Term)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

BLR181J

Conjugate

Unconjugated

Gene

Nos2

Gene Alias

Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

18126

Content And Storage

2-8°C

Form

Liquid

Description

  • Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections
  • iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
  • Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
  • NO production is mediated by members of the nitric oxide synthase (NOS) family
  • iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
  • NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
  • Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
  • All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
  • iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
  • Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
  • Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
  • After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
  • Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
  • Diseases associated with iNOS dysfunction include achalasia and impotence.

Compare Similar Items

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Img

Thermo Scientific

PIMA544541

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Antigen:
iNOS

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
BBS with 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
P29477

Gene Symbols:
Nos2

Immunogen:
Between 1094 And 1144 (C-Term)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
BLR181J

Conjugate:
Unconjugated

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
18126

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544543

--


Antigen:
iNOS

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
P35228

Gene Symbols:
Nos2

Immunogen:
Between 1103 And 1153 (C-Term)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
BLR188J

Conjugate:
Unconjugated

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
4843

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544544

--


Antigen:
iNOS

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
P35228

Gene Symbols:
Nos2

Immunogen:
Between 1103 And 1153 (C-Term)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
BLR188J

Conjugate:
Unconjugated

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
4843

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544546

--


Antigen:
25-OH Vitamin D3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
25-OH Vitamin D3 Antibody-antigen Complex.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
__

Isotype:
IgG

Applications:
ELISA

Clone:
RM428

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
25-hydroxy vitamin D, 25-hydroxyvitamin D, 25-OH Vitamin D

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
Liquid