PIMA544551
Acetyl-Histone H2A.X (Lys9) Recombinant Rabbit Monoclonal Antibody (RM446), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544551-Each-of-1 | In Stock | ₹ 41,539.38 |
PIMA544551 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,539.38
GST (18%): ₹ 7,477.088
Total Price: ₹ 49,016.468
Antigen
Acetyl-Histone H2A.X (Lys9)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P16104
Gene Symbols
H2AX
Immunogen
A peptide corresponding to acetyl-Histone H2A.X (Lys9).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Luminex, Western Blot
Clone
RM446
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3014
Content And Storage
-20°C
Isotype
IgG
Related Products
Description
- This antibody reacts to human p504s/AMACR Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Acetyl-Histone H2A.X (Lys9)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P16104
Gene Symbols: H2AX
Immunogen: A peptide corresponding to acetyl-Histone H2A.X (Lys9).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Luminex, Western Blot
Clone: RM446
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3014
Content And Storage: -20°C
Isotype: IgG
Antigen:
Acetyl-Histone H2A.X (Lys9)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P16104
Gene Symbols:
H2AX
Immunogen:
A peptide corresponding to acetyl-Histone H2A.X (Lys9).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Luminex, Western Blot
Clone:
RM446
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3014
Content And Storage:
-20°C
Isotype:
IgG
Antigen: H2BK5ac
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: A0A2R8Y619, O60814, P06899, P0C1H6, P23527, P33778, P57053, P58876, P62807, Q16778, Q5QNW6, Q7Z2G1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880
Gene Symbols: H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, LOC102724334
Immunogen: An acetyl-peptide corresponding to Acetyl-Histone H2B (Lys5).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Luminex, Western Blot
Clone: RM455
Conjugate: Unconjugated
Gene: H2BW2
Gene Alias: 2610022J01Rik, Acetyl-Histone H2, Acetyl-Histone H2B K5, Acetyl-Histone H2B Lys5, AV127319, bA317E16.3, dJ160A22.3, dJ193B12.2, dJ221C16.3, dJ221C16.6, dJ221C16.8, dJ97D16.4, GL105, H2B, H2B 291A, H2B 291B, H2b 613, H2B GL105, H2B histone family member M, H2B histone family member W testis-specific, H2B histone family member W, testis specific, H2B histone family, member A, H2B histone family, member B, H2B histone family, member C, H2B histone family, member D, H2B histone family, member E, H2B histone family, member F, H2B histone family, member J, H2B histone family, member K, H2B histone family, member L, H2B histone family, member M, H2B histone family, member N, H2B histone family, member Q, H2B histone family, member R, H2B histone family, member S, H2B histone family, member T, H2B histone family, member U, (testis-specific), H2B histone family, member W, testis-specific, H2B K, H2B type 12, H2B.1, H2B.1A, H2B.1B, H2B.2, H2B/a, H2B/b, H2B/c, H2B/d, H2B/e, H2B/f, H2B/g, H2B/h, H2B/I, H2B/j, H2B/k, H2B/l, H2B/n, H2B/q, H2B/r, H2B/S, H2b-143, h2B-221, H2b-291b, H2b-613, H2Bb, H2BC10, H2bc4, H2BC6, H2BC7, H2BC8, H2b-f, H2BFA, H2BFAiii, H2BFB, H2BFC, H2BFD, H2BFE, H2BFF, H2BFG, H2BFH, H2BFJ, H2BFK, H2BFL, H2BFM, H2BFN, H2BFQ, H2BFR, H2bfs, H2BFT, H2BFU, H2BFWT, H2BGL105, H2BJ, H2b-j, H2BK, H2BK12ac, H2BK15ac, H2BK5ac, H2b-l, H2BLys5ac, H2b-n, H2BQ, H2BS14, H2BS14p, HIRA-interacting protein 1, HIRA-interacting protein 2, HIRIP1, HIRIP2, Hist1h2ba, Hist1h2bb, HIST1H2BC, HIST1H2BD, Hist1h2be, Hist1h2bf, Hist1h2bg, HIST1H2BH, HIST1H2BI, HIST1H2BJ, HIST1H2BK, Hist1h2bl, Hist1h2bm, Hist1h2bn, HIST1H2BO, HIST1H3I, Hist2h2be, HIST2H2BF, Hist3h2bb, histone 1, H2ba, histone 1, H2bb, histone 1, H2bc, histone 1, H2bd, histone 1, H2bg, histone 1, H2bh, histone 1, H2bi, histone 1, H2bj, histone 1, H2bk, histone 1, H2bl, histone 1, H2bm, histone 1, H2bn, histone 1, H2bo, histone 2, H2be, Histone 2B, histone 3, H2bb, histone cluster 1, H2ba, histone cluster 1, H2bb, histone cluster 1, H2bc, histone cluster 1, H2bd, histone cluster 1, H2bg, histone cluster 1, H2bh, histone cluster 1, H2bi, histone cluster 1, H2bj, histone cluster 1, H2bk, histone cluster 1, H2bl, histone cluster 1, H2bm, histone cluster 1, H2bn, histone cluster 1, H2bo, histone cluster 2, H2be, histone cluster 2, H2bf, histone cluster 3, H2bb, histone family member, histone H2B, histone H2B type 1-A, Histone H2B type 1-B, histone H2B type 1-C/E/F/G/I, Histone H2B type 1-C/E/G, histone H2B type 1-D, Histone H2B type 1-F/J/L, histone H2B type 1-H, Histone H2B type 1-J, histone H2B type 1-K, Histone H2B type 1-L, histone H2B type 1-M, Histone H2B type 1-N, histone H2B type 1-O, Histone H2B type 2-E, histone H2B type 2-F, Histone H2B type 3-B, histone H2B type F-M, Histone H2B type F-S, histone H2B type F-S-like, histone H2B type W-T, Histone H2B, testis, Histone H2B.1, histone H2B.1 A, Histone H2B.1 B, histone H2B.2, Histone H2B.a, histone H2B.b, Histone H2B.c, histone H2B.d, Histone H2B.e, histone H2B.f, Histone H2B.g, Histone H2B.h, Histone H2B.I, Histone H2B.j, histone H2B.k, Histone H2B.l, histone H2B.n, Histone H2B.q, histone H2B.r, Histone H2B.s, histone H2B-GL105, LOC102724334, MGC125414, MGC125415, MGC125416, MGC9388, R74621, RP1-193B12.10, STBP, T25626, testis-specific histone 2b, testis-specific histone H2B, Th2b, TSH2B, TSH2B.1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 102724334, 114483833, 128312, 158983, 255626, 286436, 3017, 3018, 440689, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970
Content And Storage: -20°C
Isotype: IgG
Antigen:
H2BK5ac
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
A0A2R8Y619, O60814, P06899, P0C1H6, P23527, P33778, P57053, P58876, P62807, Q16778, Q5QNW6, Q7Z2G1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880
Gene Symbols:
H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, LOC102724334
Immunogen:
An acetyl-peptide corresponding to Acetyl-Histone H2B (Lys5).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Luminex, Western Blot
Clone:
RM455
Conjugate:
Unconjugated
Gene:
H2BW2
Gene Alias:
2610022J01Rik, Acetyl-Histone H2, Acetyl-Histone H2B K5, Acetyl-Histone H2B Lys5, AV127319, bA317E16.3, dJ160A22.3, dJ193B12.2, dJ221C16.3, dJ221C16.6, dJ221C16.8, dJ97D16.4, GL105, H2B, H2B 291A, H2B 291B, H2b 613, H2B GL105, H2B histone family member M, H2B histone family member W testis-specific, H2B histone family member W, testis specific, H2B histone family, member A, H2B histone family, member B, H2B histone family, member C, H2B histone family, member D, H2B histone family, member E, H2B histone family, member F, H2B histone family, member J, H2B histone family, member K, H2B histone family, member L, H2B histone family, member M, H2B histone family, member N, H2B histone family, member Q, H2B histone family, member R, H2B histone family, member S, H2B histone family, member T, H2B histone family, member U, (testis-specific), H2B histone family, member W, testis-specific, H2B K, H2B type 12, H2B.1, H2B.1A, H2B.1B, H2B.2, H2B/a, H2B/b, H2B/c, H2B/d, H2B/e, H2B/f, H2B/g, H2B/h, H2B/I, H2B/j, H2B/k, H2B/l, H2B/n, H2B/q, H2B/r, H2B/S, H2b-143, h2B-221, H2b-291b, H2b-613, H2Bb, H2BC10, H2bc4, H2BC6, H2BC7, H2BC8, H2b-f, H2BFA, H2BFAiii, H2BFB, H2BFC, H2BFD, H2BFE, H2BFF, H2BFG, H2BFH, H2BFJ, H2BFK, H2BFL, H2BFM, H2BFN, H2BFQ, H2BFR, H2bfs, H2BFT, H2BFU, H2BFWT, H2BGL105, H2BJ, H2b-j, H2BK, H2BK12ac, H2BK15ac, H2BK5ac, H2b-l, H2BLys5ac, H2b-n, H2BQ, H2BS14, H2BS14p, HIRA-interacting protein 1, HIRA-interacting protein 2, HIRIP1, HIRIP2, Hist1h2ba, Hist1h2bb, HIST1H2BC, HIST1H2BD, Hist1h2be, Hist1h2bf, Hist1h2bg, HIST1H2BH, HIST1H2BI, HIST1H2BJ, HIST1H2BK, Hist1h2bl, Hist1h2bm, Hist1h2bn, HIST1H2BO, HIST1H3I, Hist2h2be, HIST2H2BF, Hist3h2bb, histone 1, H2ba, histone 1, H2bb, histone 1, H2bc, histone 1, H2bd, histone 1, H2bg, histone 1, H2bh, histone 1, H2bi, histone 1, H2bj, histone 1, H2bk, histone 1, H2bl, histone 1, H2bm, histone 1, H2bn, histone 1, H2bo, histone 2, H2be, Histone 2B, histone 3, H2bb, histone cluster 1, H2ba, histone cluster 1, H2bb, histone cluster 1, H2bc, histone cluster 1, H2bd, histone cluster 1, H2bg, histone cluster 1, H2bh, histone cluster 1, H2bi, histone cluster 1, H2bj, histone cluster 1, H2bk, histone cluster 1, H2bl, histone cluster 1, H2bm, histone cluster 1, H2bn, histone cluster 1, H2bo, histone cluster 2, H2be, histone cluster 2, H2bf, histone cluster 3, H2bb, histone family member, histone H2B, histone H2B type 1-A, Histone H2B type 1-B, histone H2B type 1-C/E/F/G/I, Histone H2B type 1-C/E/G, histone H2B type 1-D, Histone H2B type 1-F/J/L, histone H2B type 1-H, Histone H2B type 1-J, histone H2B type 1-K, Histone H2B type 1-L, histone H2B type 1-M, Histone H2B type 1-N, histone H2B type 1-O, Histone H2B type 2-E, histone H2B type 2-F, Histone H2B type 3-B, histone H2B type F-M, Histone H2B type F-S, histone H2B type F-S-like, histone H2B type W-T, Histone H2B, testis, Histone H2B.1, histone H2B.1 A, Histone H2B.1 B, histone H2B.2, Histone H2B.a, histone H2B.b, Histone H2B.c, histone H2B.d, Histone H2B.e, histone H2B.f, Histone H2B.g, Histone H2B.h, Histone H2B.I, Histone H2B.j, histone H2B.k, Histone H2B.l, histone H2B.n, Histone H2B.q, histone H2B.r, Histone H2B.s, histone H2B-GL105, LOC102724334, MGC125414, MGC125415, MGC125416, MGC9388, R74621, RP1-193B12.10, STBP, T25626, testis-specific histone 2b, testis-specific histone H2B, Th2b, TSH2B, TSH2B.1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
102724334, 114483833, 128312, 158983, 255626, 286436, 3017, 3018, 440689, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970
Content And Storage:
-20°C
Isotype:
IgG
Antigen: AKT1 (E17K Mutant)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P31749
Gene Symbols: AKT1
Immunogen: A peptide corresponding to the Akt E17K Mutant. The immunogen range is a synthetic peptide within amino acids 1-100 of Akt with E17K mutant.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone: RM336
Conjugate: Biotin
Gene: AKT1
Gene Alias: AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 207
Content And Storage: -20°C
Isotype: IgG
Antigen:
AKT1 (E17K Mutant)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P31749
Gene Symbols:
AKT1
Immunogen:
A peptide corresponding to the Akt E17K Mutant. The immunogen range is a synthetic peptide within amino acids 1-100 of Akt with E17K mutant.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM336
Conjugate:
Biotin
Gene:
AKT1
Gene Alias:
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
207
Content And Storage:
-20°C
Isotype:
IgG
Antigen: B-Raf (V600E)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P15056
Gene Symbols: BRAF
Immunogen: A peptide corresponding to BRAF V600E mutant. The immunogen range is a synthetic peptide within amino acids 550-650 of Akt with V600E mutant.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: RM8
Conjugate: Biotin
Gene: BRAF
Gene Alias: __
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 673
Content And Storage: -20°C
Isotype: IgG
Antigen:
B-Raf (V600E)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P15056
Gene Symbols:
BRAF
Immunogen:
A peptide corresponding to BRAF V600E mutant. The immunogen range is a synthetic peptide within amino acids 550-650 of Akt with V600E mutant.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM8
Conjugate:
Biotin
Gene:
BRAF
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
673
Content And Storage:
-20°C
Isotype:
IgG