PIMA544636

Complement C3b Monoclonal Antibody (11-10), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA544636-Each-of-1 In Stock ₹ 41,068.80

PIMA544636 - Each of 1

₹ 41,068.80

In Stock

Quantity

1

Base Price: ₹ 41,068.80

GST (18%): ₹ 7,392.384

Total Price: ₹ 48,461.184

Antigen

Complement C3b

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P01024

Gene Symbols

C3

Immunogen

Synthetic peptide within human Complement C3(beta chain) 480-560.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

11-10

Conjugate

Unconjugated

Gene

C3

Gene Alias

Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

718

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

Description

  • Inactive complement component 3b (iC3b) is a 42kDa neoantigen present in blood serum
  • Cleavage of C3b into iC3b by the protease factor I, in the presence of cofactors, changes the structure and resulting binding properties, preventing binding by complement factor B and properdin
  • This prevents further progression of the complement pathway, providing another mechanism by which the complement pathway may be regulated
  • iC3b is thought to play a role in inducing tolerance, binding complement receptor type 3 on antigen presenting cells and stimulating them to produce transforming growth factor beta2 and interleukin-10
  • It is thought to stimulate B-cells via the CD21 receptor providing a link between the innate and adaptive immune responses
  • Additionally iC3b acts as an opsonin which is recognised by complement receptor 3 expressed on leukocytes or complement receptor of the immunoglobulin superfamily (CRIg) on Kupffer cells, stimulating phagocytosis of the tagged cells
  • iC3b levels are often elevated in diseases such as Systemic Lupus Erythematosis and Rheumatoid arthritis.

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Img

Thermo Scientific

PIMA544636

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Antigen:
Complement C3b

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P01024

Gene Symbols:
C3

Immunogen:
Synthetic peptide within human Complement C3(beta chain) 480-560.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
11-10

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA544638

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Antigen:
Lambda light chain

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P01701, P0CG04

Gene Symbols:
IGL, IGLC1, IGLV, IGLV1-51

Immunogen:
Synthetic peptide within human BMP2 aa 1-106.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
36-59

Conjugate:
Unconjugated

Gene:
IGLV1-51

Gene Alias:
Bence Jones Protein; BJP; Clambda1; Ig lambda chain V-I region BL2; IgL; Igl@; IGLC; IGLC 1/2/3; IGLC1; Igl-C1; IGLL5; IGLV; IGLV@; immmunoglobulin lambda light chain variable region; Immunoglobulin L; immunoglobulin lambda chain complex; immunoglobulin lambda constant 1; immunoglobulin lambda constant 7; immunoglobulin lambda light chain; immunoglobulin lambda light chain constant region; immunoglobulin lambda light chain V-J region; immunoglobulin lambda variable cluster; Lambda LC; lambda-immunoglobulin; LOC100060608; Mcg Marker; Paraprotein

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
28820, 3535, 3537, 3546

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

PIMA544640

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Antigen:
JMJD1B

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q6ZPY7, Q7LBC6

Gene Symbols:
KDM3B

Immunogen:
Recombinant protein within human KDM3B aa 251-500.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
1A8

Conjugate:
Unconjugated

Gene:
KDM3B

Gene Alias:
5830462I21Rik; 5qNCA; C5orf7; JHDM2B; JmjC domain-containing histone demethylation protein 2B; JMJD1B; jumonji domain containing 1B; jumonji domain-containing protein 1B; KDM3B; KDM3B lysine (K)-specific demethylase 3B; KIAA1082; lysine (K)-specific demethylase 3B; lysine demethylase 3B; lysine-specific demethylase 3B; mKIAA1082; NET22; Nuclear protein 5qNCA

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
277250, 51780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

PIMA544643

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Antigen:
IL-6

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P05231

Gene Symbols:
Il6

Immunogen:
Recombinant full length of human IL6 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA

Clone:
PS00-21

Conjugate:
Unconjugated

Gene:
Il6

Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG