PIMA544751
UFD1L Recombinant Rabbit Monoclonal Antibody (JE64-80), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544751-Each-of-1 | In Stock | ₹ 41,068.80 |
PIMA544751 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,068.80
GST (18%): ₹ 7,392.384
Total Price: ₹ 48,461.184
Antigen
UFD1L
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P70362, Q92890, Q9ES53
Gene Symbols
UFD1
Immunogen
Synthetic peptide within human UFD1L aa 11-60/307.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
JE64-80
Conjugate
Unconjugated
Gene
UFD1
Gene Alias
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
22230, 7353, 84478
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Ubiquitin-mediated proteolysis requires the transfer of ubiquitin (Ub) to lysine groups on selected cellular proteins, which then potentiates the proteolytic degradation of these protein conjugates by the 26S proteasome
- Ub-fusions are cleaved by Ub-specific processing proteases (UBps) or alternatively by the Ub-fusion degradation (UFD) pathway
- The UBP pathway targets the C-terminal glycine residue on Ub that is involved in the formation of Ub-conjugates, while UFD proteins preferentially cleave Ub-conjugated proteins that contain an amino acid substitution at this glycine residue
- The UFD1 protein was originally characterized in the yeast S
- cerevisiae and subsequently, the human homolog UFD1 or UFD1L was identified
- In vitro, UFD1 attenuates the degradation of Ub-fusions, which have a proline or valine residue substituted at the Gly76 moiety, by the selective multiubiquitination of the Ub chain of the Ub-conjugate
- Mutations within the UFD1 gene are implicated in the development of CATCH22 syndrome, which is characterized by cardiac defects, cleft palate and hypocalcemia, suggesting that this proteolytic pathway may be involved in the progression of these developmental defects.
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Antigen: UFD1L
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P70362, Q92890, Q9ES53
Gene Symbols: UFD1
Immunogen: Synthetic peptide within human UFD1L aa 11-60/307.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: JE64-80
Conjugate: Unconjugated
Gene: UFD1
Gene Alias: RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 22230, 7353, 84478
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
UFD1L
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P70362, Q92890, Q9ES53
Gene Symbols:
UFD1
Immunogen:
Synthetic peptide within human UFD1L aa 11-60/307.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
JE64-80
Conjugate:
Unconjugated
Gene:
UFD1
Gene Alias:
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
22230, 7353, 84478
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: Septin-8
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: B0BNF1, Q8CHH9, Q92599
Gene Symbols: SEPTIN8
Immunogen: Synthetic peptide within human Septin 8 aa 41-90/483.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: JE64-99
Conjugate: Unconjugated
Gene: SEPTIN8
Gene Alias: 2-Sep; AW046166; EMBL:AAI58797.1, ECO:0000312; KIAA0202; mKIAA0202; RGD:1308449}; SEP2; Sepl; Sept8; sept8 {ECO:0000312; septin 8; Septin8; septin-8; septin-8 {ECO:0000250; UniProtKB:Q8CHH9}
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20362, 23176, 303135
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Septin-8
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
B0BNF1, Q8CHH9, Q92599
Gene Symbols:
SEPTIN8
Immunogen:
Synthetic peptide within human Septin 8 aa 41-90/483.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
JE64-99
Conjugate:
Unconjugated
Gene:
SEPTIN8
Gene Alias:
2-Sep; AW046166; EMBL:AAI58797.1, ECO:0000312; KIAA0202; mKIAA0202; RGD:1308449}; SEP2; Sepl; Sept8; sept8 {ECO:0000312; septin 8; Septin8; septin-8; septin-8 {ECO:0000250; UniProtKB:Q8CHH9}
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20362, 23176, 303135
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: WDR1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O75083
Gene Symbols: WDR1
Immunogen: Synthetic peptide within human WDR1 aa 301-350/606.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: JE64-32
Conjugate: Unconjugated
Gene: WDR1
Gene Alias: Actin-interacting protein 1; Aip1; D5Wsu185e; epididymis secretory protein Li 52; HEL-S-52; NORI-1; rede; WD repeat domain 1; WD repeat protein 1; WD repeat-containing protein 1; WD40 repeat protein 1; Wdr1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 9948
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
WDR1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O75083
Gene Symbols:
WDR1
Immunogen:
Synthetic peptide within human WDR1 aa 301-350/606.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
JE64-32
Conjugate:
Unconjugated
Gene:
WDR1
Gene Alias:
Actin-interacting protein 1; Aip1; D5Wsu185e; epididymis secretory protein Li 52; HEL-S-52; NORI-1; rede; WD repeat domain 1; WD repeat protein 1; WD repeat-containing protein 1; WD40 repeat protein 1; Wdr1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
9948
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: TRIM24
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O15164
Gene Symbols: TRIM24
Immunogen: Synthetic peptide within human TRIM24 aa 405-455/1,050.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: JE64-31
Conjugate: Unconjugated
Gene: TRIM24
Gene Alias: A130082H20Rik; Ab2-427; AI447469; D430004I05Rik; E3 ubiquitin-protein ligase TRIM24; hTIF1; PTC6; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; RNF82; TF1A; Tif1; Tif1a; TIF1alpha; TIF1-alpha; Transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; transcriptional intermediary factor 1, alpha; Trim24; tripartite motif containing 24; tripartite motif-containing 24; tripartite motif-containing protein 24
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8805
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
TRIM24
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O15164
Gene Symbols:
TRIM24
Immunogen:
Synthetic peptide within human TRIM24 aa 405-455/1,050.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
JE64-31
Conjugate:
Unconjugated
Gene:
TRIM24
Gene Alias:
A130082H20Rik; Ab2-427; AI447469; D430004I05Rik; E3 ubiquitin-protein ligase TRIM24; hTIF1; PTC6; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; RNF82; TF1A; Tif1; Tif1a; TIF1alpha; TIF1-alpha; Transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; transcriptional intermediary factor 1, alpha; Trim24; tripartite motif containing 24; tripartite motif-containing 24; tripartite motif-containing protein 24
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8805
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG