PIMA544843

SOS1 Recombinant Rabbit Monoclonal Antibody (JE30-06), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544843-Each-of-1 In Stock ₹ 41,068.80

PIMA544843 - Each of 1

₹ 41,068.80

In Stock

Quantity

1

Base Price: ₹ 41,068.80

GST (18%): ₹ 7,392.384

Total Price: ₹ 48,461.184

Antigen

SOS1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q07889, Q62245

Gene Symbols

SOS1

Immunogen

Recombinant protein within human SOS1 aa 1-150/1,333.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Western Blot

Clone

JE30-06

Conjugate

Unconjugated

Gene

SOS1

Gene Alias

4430401P03Rik; 9630010N06; AI449023; G GINGF; GF1; GGF1; GINGF; gingival fibromatosis; gingival fibromatosis, hereditary, 1; guanine nucleotide exchange factor; guanine nucleotide releasing factor; HGF; NS4; ras guanine exchange factor; son of sevenless homolog 1; Son of sevenless homolog 1 (Drosophila); son-of-sevenless 1; SOS Ras/Rac guanine nucleotide exchange factor 1; SOS1; SOS-1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20662, 313845, 6654

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Description

  • Son of sevenless (SOS) is a guanine nucleotide exchange factor that activates Ras in response to growth factor stimulation
  • Sos1, and its closely related Sos2 paralog, are comprised of an N-terminal histone-binding domain, a RacGEF catalytic (DH) domain juxtaposed with a PH domain, a Ras exchanger motif (REM) domain, a RasGEF catalytic domain, and a C-terminal proline-rich region
  • Sos1 catalyzes the GDP-GTP exchange within the membrane-bound GTPase Ras and thereby switches on a key signaling circuit that involves the activation of MAPK cascade central to cellular proliferation, survival and differentiation
  • Growth factor stimulation rapidly induces the phosphorylation of Sos on multiple serine and threonine sites
  • Phosphorylation of residues within the Sos C-terminus by the MAP/ERK kinase disrupts the Grb2-Sos complex.

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Img

Thermo Scientific

PIMA544843

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Antigen:
SOS1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q07889, Q62245

Gene Symbols:
SOS1

Immunogen:
Recombinant protein within human SOS1 aa 1-150/1,333.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
JE30-06

Conjugate:
Unconjugated

Gene:
SOS1

Gene Alias:
4430401P03Rik; 9630010N06; AI449023; G GINGF; GF1; GGF1; GINGF; gingival fibromatosis; gingival fibromatosis, hereditary, 1; guanine nucleotide exchange factor; guanine nucleotide releasing factor; HGF; NS4; ras guanine exchange factor; son of sevenless homolog 1; Son of sevenless homolog 1 (Drosophila); son-of-sevenless 1; SOS Ras/Rac guanine nucleotide exchange factor 1; SOS1; SOS-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20662, 313845, 6654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

PIMA544844

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Antigen:
PIAS1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O75925, O88907

Gene Symbols:
PIAS1

Immunogen:
Synthetic peptide within human PIAS1 aa 71-120/651.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JE36-84

Conjugate:
Unconjugated

Gene:
PIAS1

Gene Alias:
2900068C24Rik; AR interacting protein; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein transferase PIAS1; GBP; Gu binding protein; GU/RH-II; gu-binding protein; PIAS1; protein inhibitor of activated STAT 1; protein inhibitor of activated STAT protein 1; protein inhibitor of activated STAT, 1; protein inhibitor of activated STAT-1; RING-type E3 ubiquitin transferase PIAS1; RNA helicase II-binding protein; zinc finger, MIZ-type containing 3; ZMIZ3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
56469, 8554

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

PIMA544845

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Antigen:
FHL1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q13642, Q9WUH4

Gene Symbols:
FHL1

Immunogen:
Synthetic peptide within human FHL1 aa 6-55/323.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
JE40-35

Conjugate:
Unconjugated

Gene:
FHL1

Gene Alias:
bA535K18.1; cb1039; fhl; Fhl1; FHL-1; FHL1A; fhl1b; fhla; FLH1A; four and a half LIM domains; four and a half LIM domains 1; four and a half LIM domains 1a; four and a half LIM domains 1b; four and a half LIM domains 1b; four and a half LIM domains protein 1b; four and a half LIM domains a; four and a half LIM domains protein 1; four and a half LIM domains protein 1; four and a half LIM domains protein 1a; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYOT; KYO-T; LIM protein; LIM protein SLIMMER; MGC111107; RAM14-1; RBMX1A; RBMX1B; RBP-associated molecule 14-1; RP11-535K18.1; skeletal muscle LIM-protein 1; SLIM; SLIM1; SLIM-1; SLIMMER; XMPMA; zgc:92025

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2273, 25177

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

PIMA544851

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Antigen:
CAP1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q01518

Gene Symbols:
CAP1

Immunogen:
Synthetic peptide within human CAP1 aa 10-59/475.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
JE61-08

Conjugate:
Unconjugated

Gene:
CAP1

Gene Alias:
adenylate cyclase associated protein 1; adenylyl cyclase-associated CAP protein, yeast homolog 1; adenylyl cyclase-associated protein 1; CAP; CAP 1; CAP, adenylate cyclase-associated protein 1; CAP, adenylate cyclase-associated protein 1 (yeast); CAP1; CAP1-PEN; cyclase-associated protein homologue; Mch1; RP11-115D7.1; testis secretory sperm-binding protein Li 218p

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10487

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG