PIMA544921

GNAS Monoclonal Antibody (A8F12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544921-Each-of-1 In Stock ₹ 41,068.80

PIMA544921 - Each of 1

₹ 41,068.80

In Stock

Quantity

1

Base Price: ₹ 41,068.80

GST (18%): ₹ 7,392.384

Total Price: ₹ 48,461.184

Antigen

GNAS

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O95467, P63092, P63094, P84996, Q5JWF2, Q63803, Q6R0H6, Q6R0H7, Q9Z0F1

Gene Symbols

GNAS

Immunogen

Recombinant protein within human GNAS aa 2-251.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

A8F12

Conjugate

Unconjugated

Gene

GNAS

Gene Alias

5530400H20Rik; A930027G11Rik; Adenylate cyclase-stimulating G alpha protein; AHO; ALEX; GNAS; NESP55; alpha-stimulatory subunit of GTP-binding protein; alternative gene product encoded by XL-exon; C130027O20Rik; C20orf45; dJ309F20.1.1; dJ806M20.3.3; Extra large alphas protein; G protein alpha subunit; G protein subunit alpha S; GAIPIRRH peptide; G-alpha-8; Galphas; Gnas; GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus; gnas {ECO:0000312; GNAS complex locus; GNAS complex locus; SCG6 (secretogranin VI); GNAS1; Gnasxl; Gnpas; GPIPIRRH peptide; GPSA; Gs alpha subunit; GSA; G-SALPHA60A; GSP; GTP-binding regulatory protein (G-s-alpha).; GTP-binding regulatory protein alpha subunit exon 1; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1; guanine nucleotide binding protein alpha s; guanine nucleotide binding protein alpha subunit; guanine nucleotide binding protein, alpha stimulating activity polypeptide 1; guanine nucleotide regulatory protein; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; SCG6 (secretogranin VI); guanine nucleotide-binding protein G(s), alpha subunit; guanine nucleotide-binding protein Gs alpha1; guanine nucleotide-binding protein G-s, alpha subunit; guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1; LHAL tetrapeptide; LSAL tetrapeptide; MGC33735; MNCb-5546; Nesp; NESP55; Nespl; neuroendocrine secretory protein; neuroendocrine secretory protein 55; Oedsml; Oed-Sml; OTTHUMP00000031742; OTTHUMP00000196026; OTTHUMP00000196030; P1; P2; P3; PHP1A; PHP1B; PHP1C; POH; PORGSA1; Protein ALEX; protein ALEX; protein GNAS; protein NESP55; protein ALEX; protein GNAS; protein SCG6 (secretogranin VI); RGD:2716}; RP4-543J19.4; SCG6; secretogranin VI; SgVI; stimulatory G-protein alpha subunit; stimulatory GTP binding protein; unnamed protein product; XLalphas; XLas

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14683, 24896, 2778

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a

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Description

  • Mutations in GNAS gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseous heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors
  • This gene has a highly complex imprinted expression pattern
  • It encodes maternally, paternally, and biallelically expressed proteins which are derived from alternatively spliced transcripts with alternate 5' exons
  • Each of the upstream exons is within a differentially methylated region, commonly found in imprinted genes
  • However, the close proximity (14 kb) of two oppositely expressed promoter regions is unusual
  • In addition, one of the alternate 5' exons introduces a frameshift relative to the other transcripts, resulting in one isoform which is structurally unrelated to the others
  • An antisense transcript exists, and may regulate imprinting in this region
  • Mutations in this gene result in pseudohypoparathyroidism type 1a (PHP1a), which has an atypical autosomal dominant inheritance pattern requiring maternal transmission for full penetrance.

Compare Similar Items

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Img

Thermo Scientific

PIMA544921

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Antigen:
GNAS

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O95467, P63092, P63094, P84996, Q5JWF2, Q63803, Q6R0H6, Q6R0H7, Q9Z0F1

Gene Symbols:
GNAS

Immunogen:
Recombinant protein within human GNAS aa 2-251.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A8F12

Conjugate:
Unconjugated

Gene:
GNAS

Gene Alias:
5530400H20Rik; A930027G11Rik; Adenylate cyclase-stimulating G alpha protein; AHO; ALEX; GNAS; NESP55; alpha-stimulatory subunit of GTP-binding protein; alternative gene product encoded by XL-exon; C130027O20Rik; C20orf45; dJ309F20.1.1; dJ806M20.3.3; Extra large alphas protein; G protein alpha subunit; G protein subunit alpha S; GAIPIRRH peptide; G-alpha-8; Galphas; Gnas; GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus; gnas {ECO:0000312; GNAS complex locus; GNAS complex locus; SCG6 (secretogranin VI); GNAS1; Gnasxl; Gnpas; GPIPIRRH peptide; GPSA; Gs alpha subunit; GSA; G-SALPHA60A; GSP; GTP-binding regulatory protein (G-s-alpha).; GTP-binding regulatory protein alpha subunit exon 1; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1; guanine nucleotide binding protein alpha s; guanine nucleotide binding protein alpha subunit; guanine nucleotide binding protein, alpha stimulating activity polypeptide 1; guanine nucleotide regulatory protein; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; SCG6 (secretogranin VI); guanine nucleotide-binding protein G(s), alpha subunit; guanine nucleotide-binding protein Gs alpha1; guanine nucleotide-binding protein G-s, alpha subunit; guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1; LHAL tetrapeptide; LSAL tetrapeptide; MGC33735; MNCb-5546; Nesp; NESP55; Nespl; neuroendocrine secretory protein; neuroendocrine secretory protein 55; Oedsml; Oed-Sml; OTTHUMP00000031742; OTTHUMP00000196026; OTTHUMP00000196030; P1; P2; P3; PHP1A; PHP1B; PHP1C; POH; PORGSA1; Protein ALEX; protein ALEX; protein GNAS; protein NESP55; protein ALEX; protein GNAS; protein SCG6 (secretogranin VI); RGD:2716}; RP4-543J19.4; SCG6; secretogranin VI; SgVI; stimulatory G-protein alpha subunit; stimulatory GTP binding protein; unnamed protein product; XLalphas; XLas

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14683, 24896, 2778

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

PIMA544922

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Antigen:
SLC7A11

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9UPY5, Q9WTR6

Gene Symbols:
SLC7A11

Immunogen:
293 cell line overexpressing SLC7A11.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A7C6-R

Conjugate:
Unconjugated

Gene:
SLC7A11

Gene Alias:
9930009M05Rik; AI451155; Amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cysteine/glutamate transporter; cystine/glutamate transporter; SLC7A11; sodium independent anionic amino acid transport system; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; sut; xCT

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23657, 26570

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA544923

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Antigen:
ACSL3

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O95573

Gene Symbols:
ACSL3

Immunogen:
Recombinant protein within human ACSL3 aa 180-380.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A8F7

Conjugate:
Unconjugated

Gene:
ACSL3

Gene Alias:
2610510B12Rik; Acs3; Acsl3; acyl-CoA synthetase long chain family member 3; acyl-CoA synthetase long-chain family member 3; Arachidonate--CoA ligase; Brain acyl-CoA synthetase II; C85929; FACL3; fatty acid Coenzyme A ligase, long chain 3; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; LACS3; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 3; Long-chain-fatty-acid--CoA ligase 3; Pro2194

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2181

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

PIMA544924

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Antigen:
ACSL3

Classification:
Monoclonal

Concentration:
2.0 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O95573

Gene Symbols:
ACSL3

Immunogen:
Recombinant protein within human ACSL3 aa 180-380.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
A8F6

Conjugate:
Unconjugated

Gene:
ACSL3

Gene Alias:
2610510B12Rik; Acs3; Acsl3; acyl-CoA synthetase long chain family member 3; acyl-CoA synthetase long-chain family member 3; Arachidonate--CoA ligase; Brain acyl-CoA synthetase II; C85929; FACL3; fatty acid Coenzyme A ligase, long chain 3; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; LACS3; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 3; Long-chain-fatty-acid--CoA ligase 3; Pro2194

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2181

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1