PIMA544953

IL-28A Monoclonal Antibody (A5D6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544953-Each-of-1 In Stock ₹ 41,068.80

PIMA544953 - Each of 1

₹ 41,068.80

In Stock

Quantity

1

Base Price: ₹ 41,068.80

GST (18%): ₹ 7,392.384

Total Price: ₹ 48,461.184

Antigen

IL-28A

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

TBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q8IZJ0

Gene Symbols

IFNL2

Immunogen

Synthetic peptide within human IL28A aa 110-160.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Western Blot

Clone

A5D6

Conjugate

Unconjugated

Gene

IFNL2

Gene Alias

cytokine Zcyto20; EG330496; Ifnl2; IFN-lambda2; IFN-lambda-2; Il28a; IL-28A; ILN; interferon lambda 2; interferon lambda-2; interferon, lambda 2; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin-28A; ZCYTO20

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

282616

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a

Related Products

Img

Thermo Scientific

PIMA545069

--

Img

Thermo Scientific

PIMA544929

--

Img

Thermo Scientific

PIMA544988

--

Img

Thermo Scientific

PIMA547173

--

Img

Thermo Scientific

PIMA544986

--

Img

Thermo Scientific

PIMA544987

--

Img

Thermo Scientific

PIMA545044

--

Img

Thermo Scientific

PIMA544950

--

Description

  • IL-28A belongs to the IFN lambda family, a novel family of cytokines within the IL-10 superfamily
  • The three members of this family are IL-29 (IFN lambda 1), IL-28A (IFN lambda 2), and IL-28B (IFN lambda 3), and are also known as the type III Interferons.The IFN lambdas signal through a heterodimeric receptor of which one subunit, IL-10R2, is shared with other members of the superfamily
  • The second subunit, IFN lambda R1 or IL-28R alpha, is unique to the IFN lambdas
  • Signaling occurs through the Jak/STAT pathway in a similar manner as the type I IFN (IFN alpha/beta) and activates many of the same genes despite low sequence homology between the cytokines and receptors in the two families
  • Both IFN families display antiviral activity through the induction of antiviral protein production in target cells and the upregulation of MHC class I expression
  • These proteins also exhibit antiproliferative and antitumor effects, making them a possible alternative to IFN alpha cancer therapies
  • Unlike the type I IFN, which are able to stimulate most cells, response to IFN lambda stimulation appears to be limited to dendritic and some tumor cells due to the limited expression of IFN lambda R1
  • Another notable difference is the ability of the IFN lambda stimulation to drive dendritic cells towards the production of CD4+CD25+FoxP3+ regulatory T cells, suggesting a possible immunoregulatory role

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA544953

--


Antigen:
IL-28A

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
TBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q8IZJ0

Gene Symbols:
IFNL2

Immunogen:
Synthetic peptide within human IL28A aa 110-160.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
A5D6

Conjugate:
Unconjugated

Gene:
IFNL2

Gene Alias:
cytokine Zcyto20; EG330496; Ifnl2; IFN-lambda2; IFN-lambda-2; Il28a; IL-28A; ILN; interferon lambda 2; interferon lambda-2; interferon, lambda 2; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin-28A; ZCYTO20

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
282616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

PIMA544955

--


Antigen:
BRG1

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
TBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P51532

Gene Symbols:
Smarca4

Immunogen:
Synthetic peptide within human BRG1 aa 230-280.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A5C9

Conjugate:
Unconjugated

Gene:
Smarca4

Gene Alias:
ATP-dependent helicase SMARCA4; b2b508.1Clo; b2b692Clo; BAF190; BAF190A; brahma protein-like 1; BRG1; brg-1; BRG1-associated factor 190A; BRM/SWI2-related gene 1; CSS4; FLJ39786; global transcription activator homologous sequence; homeotic gene regulator; HP1-BP72; hSNF2b; mitotic growth and transcription activator; MRD16; nuclear protein GRB1; protein brahma homolog 1; Protein BRG-1; RTPS2; SMARCA4; SNF2; Snf2b; SNF2beta; SNF2-beta; SNF2L4; SNF2LB; SNF2-like 4; sucrose nonfermenting-like 4; SW1/SNF; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; transcription activator BRG1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6597

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

PIMA544958

--


Antigen:
MAPKAP1

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9BPZ7

Gene Symbols:
MAPKAP1

Immunogen:
Recombinant protein within human SIN1 aa 350-522.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A6G10

Conjugate:
Unconjugated

Gene:
MAPKAP1

Gene Alias:
AI591529; D230039K05Rik; im:7143088; JC310; MAPK associated protein 1; mapkap1; MEKK2-interacting protein 1; MGC2745; Mip1; MIP1SIN1SIN1b; mitogen activated protein kinase associated protein 1; mitogen-activated protein kinase 2-associated protein 1; mitogen-activated protein kinase associated protein 1; mSIN1; ras inhibitor MGC2745; RP11-269P11.1; SAPK interacting protein; SAPK-interacting protein 1; si:ch73-242f23.1; SIN1; SIN1b; SIN1g; stress-activated map kinase interacting protein 1; stress-activated map kinase-interacting protein 1; stress-activated protein kinase-interacting 1; target of rapamycin complex 2 subunit MAPKAP1; TORC2 subunit MAPKAP1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
79109

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

PIMA544961

--


Antigen:
PDE4D

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q08499

Gene Symbols:
Pde4d

Immunogen:
Recombinant protein within Human PDE4D aa 610-809/809.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
A7F3

Conjugate:
Unconjugated

Gene:
Pde4d

Gene Alias:
9630011N22Rik; ACRDYS2; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D; cAMP-specific phosphodiesterase PDE4D6; cAMP-specific phosphodiesterase splice variant PDE4D8; cyclic AMP specific phosphodiesterase PDE4D5A; DKFZp686M11213; Dpde3; dunce; FLJ97311; HGNC:8783; HS PDE4DN2; HSPDE4D; PDE43; Pde4d; PDE4D3; PDE4D7; PDE4DN2; phosphodiesterase 4D; Phosphodiesterase 4D cAMP-specific (dunce; phosphodiesterase 4D, cAMP specific; phosphodiesterase 4D, cAMP-specific; Phosphodiesterase 4D, cAMP-specific (dunce; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); STRK1; testicular tissue protein Li 136

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5144

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1