PIMA544996
TSC1 Monoclonal Antibody (A6F1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544996-Each-of-1 | In Stock | ₹ 41,068.80 |
PIMA544996 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,068.80
GST (18%): ₹ 7,392.384
Total Price: ₹ 48,461.184
Antigen
TSC1
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q92574, Q9EP53
Gene Symbols
TSC1
Immunogen
Recombinant protein within human Hamartin aa 401-600.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
A6F1
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
64930, 7248
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes
- The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
- TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high
- Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 decreases the ability of Rheb to stimulate TOR activity
- This is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth
- A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown.
Compare Similar Items
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Antigen: TSC1
Classification: Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q92574, Q9EP53
Gene Symbols: TSC1
Immunogen: Recombinant protein within human Hamartin aa 401-600.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: A6F1
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 64930, 7248
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen:
TSC1
Classification:
Monoclonal
Concentration:
2 mg/mL
Formulation:
PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q92574, Q9EP53
Gene Symbols:
TSC1
Immunogen:
Recombinant protein within human Hamartin aa 401-600.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
A6F1
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
64930, 7248
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1
Antigen: UCHL3
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P15374, Q91Y78, Q9JKB1
Gene Symbols: UCHL3
Immunogen: Synthetic peptide within C-terminal Human UCHL3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: JE55-94
Conjugate: Unconjugated
Gene: UCHL3
Gene Alias: RGD1561196; testicular tissue protein Li 221; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin C-terminal hydrolase L3; Ubiquitin thioesterase L3; ubiquitin thiolesterase; UCHL3; UCH-L3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 498560, 50933, 7347
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
UCHL3
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P15374, Q91Y78, Q9JKB1
Gene Symbols:
UCHL3
Immunogen:
Synthetic peptide within C-terminal Human UCHL3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
JE55-94
Conjugate:
Unconjugated
Gene:
UCHL3
Gene Alias:
RGD1561196; testicular tissue protein Li 221; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin C-terminal hydrolase L3; Ubiquitin thioesterase L3; ubiquitin thiolesterase; UCHL3; UCH-L3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
498560, 50933, 7347
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: PSA
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P07288
Gene Symbols: KLK3
Immunogen: Synthetic peptide within C-terminal Human Prostate Specific Antigen.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: JE19-84
Conjugate: Unconjugated
Gene: KLK3
Gene Alias: Antigen; antigen, prostate specific; APS; Fletcher factor; gamma-seminoprotein; hK3; Kal3; Kal-3; Kallikrein 3; kallikrein 3, plasma; kallikrein B, plasma 1; kallikrein related peptidase 3; kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; Kalp1; KALP15; Kininogenin; KLK2A1; Klk3; KLK-3; Klkb1; P-30 antigen; Pk; Plasma kallikrein; Plasma kallikrein heavy chain; Plasma kallikrein light chain; Plasma prekallikrein; prostate specific antigen; prostate-specific (APS); prostate-specific antigen; PSA; Semenogelase; seminin
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 354
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
PSA
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P07288
Gene Symbols:
KLK3
Immunogen:
Synthetic peptide within C-terminal Human Prostate Specific Antigen.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
JE19-84
Conjugate:
Unconjugated
Gene:
KLK3
Gene Alias:
Antigen; antigen, prostate specific; APS; Fletcher factor; gamma-seminoprotein; hK3; Kal3; Kal-3; Kallikrein 3; kallikrein 3, plasma; kallikrein B, plasma 1; kallikrein related peptidase 3; kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; Kalp1; KALP15; Kininogenin; KLK2A1; Klk3; KLK-3; Klkb1; P-30 antigen; Pk; Plasma kallikrein; Plasma kallikrein heavy chain; Plasma kallikrein light chain; Plasma prekallikrein; prostate specific antigen; prostate-specific (APS); prostate-specific antigen; PSA; Semenogelase; seminin
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
354
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: SIRT1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q96EB6
Gene Symbols: SIRT1
Immunogen: Synthetic peptide within C terminal human SIRT1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: JE11-04
Conjugate: Unconjugated
Gene: SIRT1
Gene Alias: 75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23411
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
SIRT1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q96EB6
Gene Symbols:
SIRT1
Immunogen:
Synthetic peptide within C terminal human SIRT1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
JE11-04
Conjugate:
Unconjugated
Gene:
SIRT1
Gene Alias:
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23411
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG