PIMA545174

Alpha A Crystallin Monoclonal Antibody (1H3.B8), PerCP, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545174-Each-of-1 In Stock ₹ 39,614.28

PIMA545174 - Each of 1

₹ 39,614.28

In Stock

Quantity

1

Base Price: ₹ 39,614.28

GST (18%): ₹ 7,130.57

Total Price: ₹ 46,744.85

Antigen

Alpha A Crystallin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

P02470, P02489, P24622, P24623

Gene Symbols

CRYAA, CRYAA2

Immunogen

Native Alpha Crystallin

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Rat

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

1H3.B8

Conjugate

PerCP

Gene

CRYAA

Gene Alias

[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

102724652, 12954, 1409, 24273, 281718

Content And Storage

4° C

Isotype

IgG1

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Description

  • 0.5 μg/mL was sufficient for detection of 100 ng purified alphaA crystalline by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary.∣Detects approximately 20kDa
  • Does not cross-react with alpha B-crystallin, beta L-crystallin, beta H- crystallin, gamma -crystallin, HSP25, HSP27 or HSP47 proteins
  • Lens proteins consist almost entirely of crystallins (about 95%)
  • Crystallins are also found vertebrate skeletal muscle tissue
  • In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
  • The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
  • Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
  • There are at least 5 different proteins comprising the beta-crystallins
  • The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
  • Alpha-Crystallin comprises 40% of total lens protein composition
  • In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
  • It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
  • Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.

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Thermo Scientific

PIMA545174

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Antigen:
Alpha A Crystallin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P02470, P02489, P24622, P24623

Gene Symbols:
CRYAA, CRYAA2

Immunogen:
Native Alpha Crystallin

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
1H3.B8

Conjugate:
PerCP

Gene:
CRYAA

Gene Alias:
[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
102724652, 12954, 1409, 24273, 281718

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545176

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Antigen:
HSP40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P25685, Q9QYJ3

Gene Symbols:
DNAJB1

Immunogen:
Recombinant Protein HSP40 (Hdj1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
3B9.E6

Conjugate:
APC

Gene:
DNAJB1

Gene Alias:
0610007I11Rik; DjB1; DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ heat shock protein family (Hsp40) member B1; dnaJ homolog subfamily B member 1; DnaJ protein homolog 1; DNAJ1; Dnajb1; HDJ1; hDj-1; Heat shock 40 kDa protein 1; Heat shock protein; HSP; HSP 40; HSP40; HSPF1; human DnaJ protein 1; NDAJB1; radial spoke 16 homolog B; RSPH16B; Sis1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3337, 361384, 81489

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545177

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Antigen:
HSP40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
P25685, Q9QYJ3

Gene Symbols:
DNAJB1

Immunogen:
Recombinant Protein HSP40 (Hdj1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
3B9.E6

Conjugate:
FITC

Gene:
DNAJB1

Gene Alias:
0610007I11Rik; DjB1; DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ heat shock protein family (Hsp40) member B1; dnaJ homolog subfamily B member 1; DnaJ protein homolog 1; DNAJ1; Dnajb1; HDJ1; hDj-1; Heat shock 40 kDa protein 1; Heat shock protein; HSP; HSP 40; HSP40; HSPF1; human DnaJ protein 1; NDAJB1; radial spoke 16 homolog B; RSPH16B; Sis1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3337, 361384, 81489

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

PIMA545178

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Antigen:
HSP40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P25685, Q9QYJ3

Gene Symbols:
DNAJB1

Immunogen:
Recombinant Protein HSP40 (Hdj1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
3B9.E6

Conjugate:
PerCP

Gene:
DNAJB1

Gene Alias:
0610007I11Rik; DjB1; DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ heat shock protein family (Hsp40) member B1; dnaJ homolog subfamily B member 1; DnaJ protein homolog 1; DNAJ1; Dnajb1; HDJ1; hDj-1; Heat shock 40 kDa protein 1; Heat shock protein; HSP; HSP 40; HSP40; HSPF1; human DnaJ protein 1; NDAJB1; radial spoke 16 homolog B; RSPH16B; Sis1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3337, 361384, 81489

Content And Storage:
4° C

Isotype:
IgG1