PIMA545219

CRYAB Monoclonal Antibody (3A10.C9), PerCP, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545219-Each-of-1 In Stock ₹ 39,614.28

PIMA545219 - Each of 1

₹ 39,614.28

In Stock

Quantity

1

Base Price: ₹ 39,614.28

GST (18%): ₹ 7,130.57

Total Price: ₹ 46,744.85

Antigen

CRYAB

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.2

Gene Accession No.

P02510, P02511, P23928

Gene Symbols

Cryab

Immunogen

Native Alpha B Crystallin

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Rat

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

3A10.C9

Conjugate

PerCP

Gene

Cryab

Gene Alias

2310001E10Rik; 3526402H21Rik; AACRYA; active transcription factor CREB; alpha B-crystallin; alpha crystallin B; alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CMD1II; CREB; CREB1; CREB-1; Crya2; Crya-2; CRYAB; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; epididymis secretory protein Li 101; heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; HspB5 protein; MFM2; P23; Renal carcinoma antigen NY-REN-27; rosenthal fiber component; transactivator protein; Y protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1410, 25420, 281719

Content And Storage

4° C

Isotype

IgG1

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Description

  • 0.5 μg/mL of MA5-45219 was sufficient for detection of 50 ng purified alpha B crystalline by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 20kDa (predicted mol.weight is approximately 21kDa)
  • Does not cross-react with alpha A-crystallin, beta L-crystallin, beta H-crystallin, gamma -crystallin, HSP25, HSP27 or HSP47 proteins
  • Lens proteins consist almost entirely of crystallins (about 95%)
  • Crystallins are also found vertebrate skeletal muscle tissue
  • In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
  • The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
  • Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
  • There are at least 5 different proteins comprising the beta-crystallins
  • The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
  • Alpha-Crystallin comprises 40% of total lens protein composition
  • In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
  • It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
  • Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.

Compare Similar Items

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Img

Thermo Scientific

PIMA545219

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Antigen:
CRYAB

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.2

Gene Accession No.:
P02510, P02511, P23928

Gene Symbols:
Cryab

Immunogen:
Native Alpha B Crystallin

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Rat

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3A10.C9

Conjugate:
PerCP

Gene:
Cryab

Gene Alias:
2310001E10Rik; 3526402H21Rik; AACRYA; active transcription factor CREB; alpha B-crystallin; alpha crystallin B; alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CMD1II; CREB; CREB1; CREB-1; Crya2; Crya-2; CRYAB; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; epididymis secretory protein Li 101; heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; HspB5 protein; MFM2; P23; Renal carcinoma antigen NY-REN-27; rosenthal fiber component; transactivator protein; Y protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1410, 25420, 281719

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545220

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Antigen:
HSP40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Full length protein HSP40 (YDJ1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Yeast

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Clone:
2A7.H6

Conjugate:
APC

Gene:
__

Gene Alias:
0610007I11Rik; DjB1; DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ heat shock protein family (Hsp40) member B1; dnaJ homolog subfamily B member 1; DnaJ protein homolog 1; DNAJ1; Dnajb1; HDJ1; hDj-1; Heat shock 40 kDa protein 1; Heat shock protein; HSP; HSP 40; HSP40; HSPF1; human DnaJ protein 1; NDAJB1; radial spoke 16 homolog B; RSPH16B; Sis1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA545221

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Antigen:
HSP40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Full length protein HSP40 (YDJ1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Yeast

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Clone:
2A7.H6

Conjugate:
FITC

Gene:
__

Gene Alias:
0610007I11Rik; DjB1; DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ heat shock protein family (Hsp40) member B1; dnaJ homolog subfamily B member 1; DnaJ protein homolog 1; DNAJ1; Dnajb1; HDJ1; hDj-1; Heat shock 40 kDa protein 1; Heat shock protein; HSP; HSP 40; HSP40; HSPF1; human DnaJ protein 1; NDAJB1; radial spoke 16 homolog B; RSPH16B; Sis1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA545222

--


Antigen:
HSP40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Full length protein HSP40 (YDJ1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Yeast

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Clone:
2A7.H6

Conjugate:
PerCP

Gene:
__

Gene Alias:
0610007I11Rik; DjB1; DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ heat shock protein family (Hsp40) member B1; dnaJ homolog subfamily B member 1; DnaJ protein homolog 1; DNAJ1; Dnajb1; HDJ1; hDj-1; Heat shock 40 kDa protein 1; Heat shock protein; HSP; HSP 40; HSP40; HSPF1; human DnaJ protein 1; NDAJB1; radial spoke 16 homolog B; RSPH16B; Sis1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Isotype:
IgG1 κ