PIMA545264

DMPO Monoclonal Antibody (N1664A), PE, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545264-Each-of-1 In Stock ₹ 38,758.68

PIMA545264 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

DMPO

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Target Species

Chemical

Form

Liquid

Target Molecule

Chemical

Applications

Microarray, ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone

N1664A

Conjugate

PE

Gene Alias

DMPO nitrone adduct

Immunogen

5,5-dimethyl-2-(8-octanoic acid)-1-pyrrolone-N-oxide conjugated to Ovalbumin

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

4° C

Isotype

IgG1

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Description

  • A 1:1,000 dilution of MA5-45264 was sufficient to detect the DMPO nitrone adducts of metmyoglobin when loaded at 100 ng/lane by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Recognizes DMPO, DMPO-octanoic acid, DMPO-protein adducts and DMPO-DNA adducts
  • Does not cross react with non-adducted proteins or DNA
  • The formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states
  • The ability to identify these species is crucial, and spin trapping has accomplished this goal
  • DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems
  • Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals
  • DMPO adducts can be generated with protein and DNA radicals.

Compare Similar Items

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Img

Thermo Scientific

PIMA545264

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Antigen:
DMPO

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Chemical

Form:
Liquid

Target Molecule:
Chemical

Applications:
Microarray, ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone:
N1664A

Conjugate:
PE

Gene Alias:
DMPO nitrone adduct

Immunogen:
5,5-dimethyl-2-(8-octanoic acid)-1-pyrrolone-N-oxide conjugated to Ovalbumin

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545266

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Antigen:
DUX4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human, Mouse

Form:
Liquid

Target Molecule:
__

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
P2B1

Conjugate:
FITC

Gene Alias:
AW822073; double homeobox; double homeobox 4; double homeobox 4-like; double homeobox B-like 1; double homeobox protein 10; Double homeobox protein 4; double homeobox protein 4/10; Dux; DUX10; Dux4; DUX4L; Duxbl; Duxbl1; EG664783; homeobox protein; RGD1311053

Immunogen:
C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

PIMA545267

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Antigen:
DUX4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human, Mouse

Form:
Liquid

Target Molecule:
__

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
P2B1

Conjugate:
PerCP

Gene Alias:
AW822073; double homeobox; double homeobox 4; double homeobox 4-like; double homeobox B-like 1; double homeobox protein 10; Double homeobox protein 4; double homeobox protein 4/10; Dux; DUX10; Dux4; DUX4L; Duxbl; Duxbl1; EG664783; homeobox protein; RGD1311053

Immunogen:
C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545278

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Antigen:
GRP78

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Bovine, Fungi, Hamster, Human, Mouse, Non-human Primate, Rabbit, Rat, X. laevis

Form:
Liquid

Target Molecule:
__

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
1H11-1H7

Conjugate:
PerCP

Gene Alias:
78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) member 5; heat shock protein family A (Hsp70) member 5 L homeolog; heat shock protein family A member 5; heavy-chain binding protein BiP; HEL-S-89n; Hsce70; hsp70; Hsp70 family ATPase KAR2; HSP70 family protein 5; HSPA 5; HSPA5; hspa5.L; hspa5a; I79_019946; immunoglobulin binding protein; immunoglobulin heavy chain-binding protein; Immunoglobulin heavy chain-binding protein homolog; J1248; KAR2; mBiP; MIF2; Sez7; SEZ-7; SSD1; Steroidogenesis-activator polypeptide; wu:fb60h09; wu:fi36d04; XAP-1; XAP-1 antigen; XELAEV_180384511mg; YJL034W; zgc:55994; zgc:77606

Immunogen:
His-tagged human GRP78

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C

Isotype:
IgG2b