PIMA545401

HCN1 Monoclonal Antibody (S70), PerCP, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545401-Each-of-1 In Stock ₹ 38,758.68

PIMA545401 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

HCN1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

O60741, O88704, Q9JKB0

Gene Symbols

HCN1

Immunogen

Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone

S70

Conjugate

PerCP

Gene

HCN1

Gene Alias

Bcng1; BCNG-1; Brain cyclic nucleotide-gated channel 1; C630013B14Rik; EIEE24; Hac2; HAC-2; Hcn1; hyperpolarization activated cyclic nucleotide gated potassium channel 1; hyperpolarization-activated cation channel 2; hyperpolarization-activated cyclic nucleotide-gated potassium channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

15165, 348980, 84390

Content And Storage

4° C

Isotype

IgG1

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Description

  • 1 μg/mL of MA5-45401 was sufficient for detection of HCN1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 100kDa
  • No cross-reactivity against HCN2
  • HCN1 includes Hyperpolarization-activated cation channels of the HCN gene family, which contribute to spontaneous rhythmic activity in both heart and brain
  • HCN1 is a member of a family of pacemaker channels activated by hyperpolarization and regulated by cyclic nucleotides
  • HCN1 and HCN2 play an important role for motor learning and neuronal integration by cerebellar Purkinje cells as well as, shaping autonomous activity of single neurons and the periodicity of network oscillations
  • The HCN1 expression is highly enriched in cerebral cortex, hippocampus, cerebellum, and facial motor nucleus
  • HCN2 is highly abundant in mamillary bodies, pontine nucleus, ventral cochlear nucleus, and nucleus of the trapezoid body
  • These variations in regional specificity of HCN channels could generate important differences in neuronal pacemaker activity across brain systems.

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Img

Thermo Scientific

PIMA545401

--


Antigen:
HCN1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O60741, O88704, Q9JKB0

Gene Symbols:
HCN1

Immunogen:
Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
S70

Conjugate:
PerCP

Gene:
HCN1

Gene Alias:
Bcng1; BCNG-1; Brain cyclic nucleotide-gated channel 1; C630013B14Rik; EIEE24; Hac2; HAC-2; Hcn1; hyperpolarization activated cyclic nucleotide gated potassium channel 1; hyperpolarization-activated cation channel 2; hyperpolarization-activated cyclic nucleotide-gated potassium channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15165, 348980, 84390

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545402

--


Antigen:
HCN1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O60741, O88704, Q9JKB0

Gene Symbols:
HCN1

Immunogen:
Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
S70

Conjugate:
PE

Gene:
HCN1

Gene Alias:
Bcng1; BCNG-1; Brain cyclic nucleotide-gated channel 1; C630013B14Rik; EIEE24; Hac2; HAC-2; Hcn1; hyperpolarization activated cyclic nucleotide gated potassium channel 1; hyperpolarization-activated cation channel 2; hyperpolarization-activated cyclic nucleotide-gated potassium channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15165, 348980, 84390

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545403

--


Antigen:
HCN2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O88703, Q9JKA9, Q9UL51

Gene Symbols:
HCN2

Immunogen:
Fusion protein amino acids 761-863 (cytoplasmic C-terminus) of rat HCN2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
S71

Conjugate:
APC

Gene:
HCN2

Gene Alias:
BCNG2; BCNG-2; brain cyclic nucleotide gated channel 2; brain cyclic nucleotide-gated channel 2; Hac1; HAC-1; HCN2; hyperpolarization activated cyclic nucleotide gated potassium channel 2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; hyperpolarization-activated cation channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; trls

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114244, 15166, 610

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545404

--


Antigen:
HCN2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
O88703, Q9JKA9, Q9UL51

Gene Symbols:
HCN2

Immunogen:
Fusion protein amino acids 761-863 (cytoplasmic C-terminus) of rat HCN2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
S71

Conjugate:
FITC

Gene:
HCN2

Gene Alias:
BCNG2; BCNG-2; brain cyclic nucleotide gated channel 2; brain cyclic nucleotide-gated channel 2; Hac1; HAC-1; HCN2; hyperpolarization activated cyclic nucleotide gated potassium channel 2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; hyperpolarization-activated cation channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; trls

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114244, 15166, 610

Content And Storage:
4° C, store in dark

Isotype:
IgG1