PIMA545407

KCNQ1 Monoclonal Antibody (N37A/10), APC, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA545407-Each-of-1 In Stock ₹ 38,758.68

PIMA545407 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

KCNQ1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

P51787, P97414, Q9Z0N7

Gene Symbols

KCNQ1

Immunogen

Fusion protein amino acids 2-101 of human KCNQ1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rat

Form

Liquid

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone

N37A/10

Conjugate

APC

Gene

KCNQ1

Gene Alias

ATFB1; ATFB3; AW559127; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; Kcnq1; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; mutant potassium voltage-gated channel KQT-like subfamily member 1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel subfamily Q member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100761481, 16535, 3784, 84020

Content And Storage

4° C

Isotype

IgG1

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Description

  • 1 μg/mL of MA5-45407 was sufficient for detection of KCNQ1 in 10 μg of COS-1 cell lysate transiently expressing KCNQ1 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 75kDa
  • Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells
  • A specific K+ channel, comprised of an alpha subunit KCNQ1 and a beta subunit KCNE1, a small protein which spans the membrane only once, is predominantly expressed in the heart and in the cochlea, and is responsible for regulating the slow, depolarization-activated potassium current
  • Mutations in the genes encoding for KCNQ1 and KCNE1 lead to cardiac disease because they directly impair electrical signaling, and mutations in KCNQ4 are implicated in the onset of deafness
  • KCNQ proteins, including KCNQ1 and KCNQ4, characteristically contain six transmembrane domains and function as tetramers
  • KCNQ4 forms heteromeric channels with KCNQ3 and is expressed in several tissues, including the cochlea, where it is present in outer hair cells.

Compare Similar Items

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Img

Thermo Scientific

PIMA545407

--


Antigen:
KCNQ1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P51787, P97414, Q9Z0N7

Gene Symbols:
KCNQ1

Immunogen:
Fusion protein amino acids 2-101 of human KCNQ1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
N37A/10

Conjugate:
APC

Gene:
KCNQ1

Gene Alias:
ATFB1; ATFB3; AW559127; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; Kcnq1; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; mutant potassium voltage-gated channel KQT-like subfamily member 1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel subfamily Q member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100761481, 16535, 3784, 84020

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545409

--


Antigen:
KCNQ1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P51787, P97414, Q9Z0N7

Gene Symbols:
KCNQ1

Immunogen:
Fusion protein amino acids 2-101 of human KCNQ1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
N37A/10

Conjugate:
PerCP

Gene:
KCNQ1

Gene Alias:
ATFB1; ATFB3; AW559127; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; Kcnq1; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; mutant potassium voltage-gated channel KQT-like subfamily member 1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel subfamily Q member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100761481, 16535, 3784, 84020

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545410

--


Antigen:
KCNQ1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P51787, P97414, Q9Z0N7

Gene Symbols:
KCNQ1

Immunogen:
Fusion protein amino acids 2-101 of human KCNQ1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
N37A/10

Conjugate:
PE

Gene:
KCNQ1

Gene Alias:
ATFB1; ATFB3; AW559127; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; Kcnq1; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; mutant potassium voltage-gated channel KQT-like subfamily member 1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel subfamily Q member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100761481, 16535, 3784, 84020

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545413

--


Antigen:
KCNQ4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P56696, Q9JK96, Q9JK97

Gene Symbols:
KCNQ4

Immunogen:
Fusion protein amino acids 2-77 of human KCNQ4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation

Clone:
N43/6

Conjugate:
PerCP

Gene:
KCNQ4

Gene Alias:
DFNA 2; DFNA2; DFNA2A; KCNQ 4; KCNQ4; KQT like 4; KQT-like 4; KV7.4; LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily KQT member 4; potassium channel KQT-like 4; potassium channel subunit alpha KvLQT4; potassium channel, voltage gated KQT-like subfamily Q, member 4; potassium channel, voltage-gated KQT-like subfamily Q, member 4; potassium voltage-gated channel KQT-like protein 4; potassium voltage-gated channel KQT-like subfamily member 4; potassium voltage-gated channel subfamily KQT member 4; potassium voltage-gated channel subfamily Q member 4; potassium voltage-gated channel, KQT-like subfamily, member 4; potassium voltage-gated channel, subfamily Q, member 4; voltage-gated potassium channel subunit Kv7.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
298496, 60613, 9132

Content And Storage:
4° C

Isotype:
IgG1