PIMA545485

GABRA1 Monoclonal Antibody (N95/35), APC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545485-Each-of-1 In Stock ₹ 38,758.68

PIMA545485 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

GABRA1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

P14867, P62812, P62813

Gene Symbols

GABRA1

Immunogen

Fusion protein amino acids 355-394 of human GABA-A-R-Alpha1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

N95/35

Conjugate

APC

Gene

GABRA1

Gene Alias

ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

14394, 2554, 29705

Content And Storage

4° C

Isotype

IgG2a

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Description

  • 1 μg/mL of MA5-45485 was sufficient for detection of alpha1 GABA receptor in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 55kDa
  • No cross-reactivity against GABA-A-R-Alpha 2 or -Alpha3
  • Gamma -aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA Receptor (GABAA-R) subtype
  • GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse
  • The GABAA-R is a multimeric subunit complex
  • To date aix alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified
  • Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-R sensitive to GABA
  • However, coexpression of a gamma-subunit is required for benzodiazepine modulation
  • The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor
  • Lastly, phosphorylation of beta-subunits of the receptor has been shown to modulate GABAA-R function.

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Thermo Scientific

PIMA545485

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Antigen:
GABRA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P14867, P62812, P62813

Gene Symbols:
GABRA1

Immunogen:
Fusion protein amino acids 355-394 of human GABA-A-R-Alpha1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
N95/35

Conjugate:
APC

Gene:
GABRA1

Gene Alias:
ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14394, 2554, 29705

Content And Storage:
4° C

Isotype:
IgG2a

Img

Thermo Scientific

PIMA545486

--


Antigen:
GABRA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
P14867, P62812, P62813

Gene Symbols:
GABRA1

Immunogen:
Fusion protein amino acids 355-394 of human GABA-A-R-Alpha1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
N95/35

Conjugate:
FITC

Gene:
GABRA1

Gene Alias:
ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14394, 2554, 29705

Content And Storage:
4° C, store in dark

Isotype:
IgG2a

Img

Thermo Scientific

PIMA545489

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Antigen:
SLC5A5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
Q63008, Q92911, Q99PN0

Gene Symbols:
SLC5A5

Immunogen:
Mannose binding protein hNIS fusion (AA468-643)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunohistochemistry (PFA fixed), Western Blot

Clone:
14F

Conjugate:
APC

Gene:
SLC5A5

Gene Alias:
Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Na+/I- symporter; Nis; SLC5A5; sodium iodide symporter; Sodium/iodide cotransporter; sodium-iodide symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; solute carrier family 5 member 5; solute carrier family 5, member 5; TDH1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114479, 114613, 6528

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545490

--


Antigen:
SLC5A5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
Q63008, Q92911, Q99PN0

Gene Symbols:
SLC5A5

Immunogen:
Mannose binding protein hNIS fusion (AA468-643)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunohistochemistry (PFA fixed), Western Blot

Clone:
14F

Conjugate:
FITC

Gene:
SLC5A5

Gene Alias:
Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Na+/I- symporter; Nis; SLC5A5; sodium iodide symporter; Sodium/iodide cotransporter; sodium-iodide symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; solute carrier family 5 member 5; solute carrier family 5, member 5; TDH1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114479, 114613, 6528

Content And Storage:
4° C, store in dark

Isotype:
IgG1