PIMA545549

EAAC1 Monoclonal Antibody (S180-41), PerCP, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545549-Each-of-1 In Stock ₹ 38,758.68

PIMA545549 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

EAAC1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

P43005, P51907

Gene Symbols

Slc1a1

Immunogen

Fusion protein amino acids 1-524 (full length) of human EAAC1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

S180-41

Conjugate

PerCP

Gene

Slc1a1

Gene Alias

D130048G10Rik; DCBXA; EAAC1; EAAC2; EAAT3; excitatory amino acid carrier 1; excitatory amino acid carrier 2; excitatory amino acid transporter 3; excitatory amino acid transporter-3; excitatory amino-acid carrier 1; glutamate transporter mEAAC2; MEAAC1; Neuronal and epithelial glutamate transporter; REAAC1; SCZD18; SLC1A1; Sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; Solute carrier family 1 A1 (brain glutamate transporter); solute carrier family 1 member 1; solute carrier family 1, member 1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

25550, 6505

Content And Storage

4° C

Isotype

IgG1

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Description

  • 5 μg of MA5-45549 was sufficient for immunoprecipitation of EAAC1 from 50 μg of rat brain lysate.∣Detects approximately 60kDa
  • L-glutamate is the major excitatory neurotransmitter in mammalian central nervous systems
  • To maintain glutamate levels below excitoxic levels, excess glutamate at excitatory synaptic clefts is removed by ion-coupled glutamate transporters
  • Four glutamate transporters have been identified: the sodium-dependent GLAST-1, GLT-1, EAAC-1 and the chloride-dependent EAAT-4
  • EAAC-1 is expressed in the CNS and also found in kidney and small intestine
  • Structural features of glutamate transporters are believed to include eight membrane-spanning alpha-helices and a loop-pore structure which is unique among secondary transporters but may resemble loop-pores found in ion channels
  • A second distinctive structural feature is the presence of a highly amphipathic membrane-spanning helix that provides a hydrophilic path through the membrane
  • Mice with homozygous deletions of the EAAC-1 transporter gene develop dicarboxylic aminoaciduria and display reduced spontaneous locomotor activity although no neurodegeneration was observed over a period of 12 months.

Compare Similar Items

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Img

Thermo Scientific

PIMA545549

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Antigen:
EAAC1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P43005, P51907

Gene Symbols:
Slc1a1

Immunogen:
Fusion protein amino acids 1-524 (full length) of human EAAC1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
S180-41

Conjugate:
PerCP

Gene:
Slc1a1

Gene Alias:
D130048G10Rik; DCBXA; EAAC1; EAAC2; EAAT3; excitatory amino acid carrier 1; excitatory amino acid carrier 2; excitatory amino acid transporter 3; excitatory amino acid transporter-3; excitatory amino-acid carrier 1; glutamate transporter mEAAC2; MEAAC1; Neuronal and epithelial glutamate transporter; REAAC1; SCZD18; SLC1A1; Sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; Solute carrier family 1 A1 (brain glutamate transporter); solute carrier family 1 member 1; solute carrier family 1, member 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25550, 6505

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545550

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Antigen:
mGluR1/mGluR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P23385, P31424, P41594, P97772, Q13255, Q3UVX5

Gene Symbols:
Grm1, Grm5

Immunogen:
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
S75-33

Conjugate:
APC

Gene:
Grm5

Gene Alias:
4930455H15Rik; 6430542K11Rik; AI850523; ENSMUSG00000075319; G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member E; Glu5R; glutamate metabotropic receptor 1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 1; glutamate receptor, metabotropic 5; Gm10828; GPRC1A; Gprc1e; Grm1; GRM5; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 1; Metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGLU1; mGlu5; mGluR1; mGluR5; mGluR5b; mGlurR1a; nmf373; PPP1R85; PPP1R86; protein phosphatase 1, regulatory subunit 85; protein phosphatase 1, regulatory subunit 86; rcw; SCAR13; wobl

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
108071, 14816, 24414, 24418, 2911, 2915

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545551

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Antigen:
mGluR1/mGluR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
P23385, P31424, P41594, P97772, Q13255, Q3UVX5

Gene Symbols:
Grm1, Grm5

Immunogen:
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
S75-33

Conjugate:
FITC

Gene:
Grm5

Gene Alias:
4930455H15Rik; 6430542K11Rik; AI850523; ENSMUSG00000075319; G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member E; Glu5R; glutamate metabotropic receptor 1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 1; glutamate receptor, metabotropic 5; Gm10828; GPRC1A; Gprc1e; Grm1; GRM5; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 1; Metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGLU1; mGlu5; mGluR1; mGluR5; mGluR5b; mGlurR1a; nmf373; PPP1R85; PPP1R86; protein phosphatase 1, regulatory subunit 85; protein phosphatase 1, regulatory subunit 86; rcw; SCAR13; wobl

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
108071, 14816, 24414, 24418, 2911, 2915

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

PIMA545552

--


Antigen:
mGluR1/mGluR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P23385, P31424, P41594, P97772, Q13255, Q3UVX5

Gene Symbols:
Grm1, Grm5

Immunogen:
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
S75-33

Conjugate:
PerCP

Gene:
Grm5

Gene Alias:
4930455H15Rik; 6430542K11Rik; AI850523; ENSMUSG00000075319; G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member E; Glu5R; glutamate metabotropic receptor 1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 1; glutamate receptor, metabotropic 5; Gm10828; GPRC1A; Gprc1e; Grm1; GRM5; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 1; Metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGLU1; mGlu5; mGluR1; mGluR5; mGluR5b; mGlurR1a; nmf373; PPP1R85; PPP1R86; protein phosphatase 1, regulatory subunit 85; protein phosphatase 1, regulatory subunit 86; rcw; SCAR13; wobl

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
108071, 14816, 24414, 24418, 2911, 2915

Content And Storage:
4° C

Isotype:
IgG1