PIMA545573
NALCN Monoclonal Antibody (S187-7), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA545573-Each-of-1 | In Stock | ₹ 38,758.68 |
PIMA545573 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
NALCN
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.
Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols
NALCN
Immunogen
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Clone
S187-7
Conjugate
FITC
Gene
NALCN
Gene Alias
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
259232, 266760, 338370
Content And Storage
4° C, store in dark
Isotype
IgG1
Related Products
Description
- 1 μg/mL of MA5-45573 was sufficient for detection of NALCN in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 200kDa
- Nalcn is a voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions
- Nalcn regulates the resting membrane potential and controls neuronal excitability (PubMed:17448995)
- Neuropeptides such as neurotensin and substance P (SP) stimulate the firing of action potentials by activating NALCN through a SRC family kinases-dependent pathway
- In addition to its baseline activity, Nalcn activity is enhanced/modulated by several GPCRs, is required for normal respiratory rhythm and neonatal survival, is involved in systemic osmoregulation by controlling the serum sodium concentration
- Nalcn is partly responsible for the substance P-induced depolarization and regulation of the intestinal pace-making activity in the interstitial cells of Cajal
- Further, Nalcn plays a critical role in both maintenance of spontaneous firing of substantia nigra pars reticulata (SNr) neurons and physiological modulation of SNr neuron excitability
- Diseases associated with NALCN include Congenital contractures of the limbs and face, Hypotonia, Developmental Delay and Hypotonia, Infantile Psychomotor Retardation And Characteristic Facies 1.
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Antigen: NALCN
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.: Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols: NALCN
Immunogen: Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: S187-7
Conjugate: FITC
Gene: NALCN
Gene Alias: A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 259232, 266760, 338370
Content And Storage: 4° C, store in dark
Isotype: IgG1
Antigen:
NALCN
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.:
Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols:
NALCN
Immunogen:
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
S187-7
Conjugate:
FITC
Gene:
NALCN
Gene Alias:
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
259232, 266760, 338370
Content And Storage:
4° C, store in dark
Isotype:
IgG1
Antigen: NALCN
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.: Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols: NALCN
Immunogen: Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: S187-7
Conjugate: PerCP
Gene: NALCN
Gene Alias: A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 259232, 266760, 338370
Content And Storage: 4° C
Isotype: IgG1
Antigen:
NALCN
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.:
Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols:
NALCN
Immunogen:
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
S187-7
Conjugate:
PerCP
Gene:
NALCN
Gene Alias:
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
259232, 266760, 338370
Content And Storage:
4° C
Isotype:
IgG1
Antigen: NALCN
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.: Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols: NALCN
Immunogen: Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: S187-7
Conjugate: PE
Gene: NALCN
Gene Alias: A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 259232, 266760, 338370
Content And Storage: 4° C
Isotype: IgG1
Antigen:
NALCN
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.:
Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols:
NALCN
Immunogen:
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
S187-7
Conjugate:
PE
Gene:
NALCN
Gene Alias:
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
259232, 266760, 338370
Content And Storage:
4° C
Isotype:
IgG1
Antigen: LRP4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.: O75096, Q8VI56, Q9QYP1
Gene Symbols: LRP4
Immunogen: Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: S207-27
Conjugate: APC
Gene: LRP4
Gene Alias: 6430526J12Rik; CLSS; CMS17; Corin; D230026E03; Kiaa0816; LDL receptor related protein 4; LDLR; LDLR dan; low density lipoprotein receptor-related protein 4; low-density lipoprotein receptor-related protein 4; LRP10; Lrp4; LRP-4; mdig; Megf7; multiple epidermal growth factor-like domains 7; SOST2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 228357, 4038, 83469
Content And Storage: 4° C
Isotype: IgG2a
Antigen:
LRP4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.:
O75096, Q8VI56, Q9QYP1
Gene Symbols:
LRP4
Immunogen:
Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
S207-27
Conjugate:
APC
Gene:
LRP4
Gene Alias:
6430526J12Rik; CLSS; CMS17; Corin; D230026E03; Kiaa0816; LDL receptor related protein 4; LDLR; LDLR dan; low density lipoprotein receptor-related protein 4; low-density lipoprotein receptor-related protein 4; LRP10; Lrp4; LRP-4; mdig; Megf7; multiple epidermal growth factor-like domains 7; SOST2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
228357, 4038, 83469
Content And Storage:
4° C
Isotype:
IgG2a