PIMA546527

CD146 Monoclonal Antibody (CL12855), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546527-Each-of-1 In Stock ₹ 36,705.24

PIMA546527 - Each of 1

₹ 36,705.24

In Stock

Quantity

1

Base Price: ₹ 36,705.24

GST (18%): ₹ 6,606.943

Total Price: ₹ 43,312.183

Antigen

CD146

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P43121

Gene Symbols

MCAM

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry

Clone

CL12855

Conjugate

Unconjugated

Gene

MCAM

Gene Alias

1-gicerin; AV025631; CD146; CD149; Cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; l-gicerin; l-gicerin precursor; l-gicerin protein; LOW QUALITY PROTEIN: cell surface glycoprotein MUC18; MCAM; melanoma adhesion molecule; melanoma cell adhesion molecule; Melanoma-associated antigen A32; melanoma-associated antigen MUC18; Muc18; mucin-18; s-endo; S-endo 1 endothelial-associated antigen; s-gicerin; s-gicerin precursor

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4162

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily
  • CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and malignant cell types
  • In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly
  • CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue
  • CD146 expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread
  • Further, CD146 could be an adhesion molecule active in neural crest cells during embryonic development
  • CD146 acts also as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Compare Similar Items

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Img

Thermo Scientific

PIMA546527

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Antigen:
CD146

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P43121

Gene Symbols:
MCAM

Immunogen:
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry

Clone:
CL12855

Conjugate:
Unconjugated

Gene:
MCAM

Gene Alias:
1-gicerin; AV025631; CD146; CD149; Cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; l-gicerin; l-gicerin precursor; l-gicerin protein; LOW QUALITY PROTEIN: cell surface glycoprotein MUC18; MCAM; melanoma adhesion molecule; melanoma cell adhesion molecule; Melanoma-associated antigen A32; melanoma-associated antigen MUC18; Muc18; mucin-18; s-endo; S-endo 1 endothelial-associated antigen; s-gicerin; s-gicerin precursor

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4162

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

PIMA546532

--


Antigen:
Calretinin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P22676, Q08331

Gene Symbols:
CALB2

Immunogen:
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Clone:
CL12836

Conjugate:
Unconjugated

Gene:
CALB2

Gene Alias:
29 kDa calbindin; 29kD calretinin; 29kDa calbindin; CAB29; CAL2; Calb2; calbindin 2; calbindin 2, (29kD, calretinin); calbindin 2, 29kDa; calbindin D29K; calretinin; CR; testicular secretory protein Li 8

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12308, 794

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

PIMA546533

--


Antigen:
Calretinin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P22676, Q08331

Gene Symbols:
CALB2

Immunogen:
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Clone:
CL12842

Conjugate:
Unconjugated

Gene:
CALB2

Gene Alias:
29 kDa calbindin; 29kD calretinin; 29kDa calbindin; CAB29; CAL2; Calb2; calbindin 2; calbindin 2, (29kD, calretinin); calbindin 2, 29kDa; calbindin D29K; calretinin; CR; testicular secretory protein Li 8

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12308, 794

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

PIMA546534

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Antigen:
Melan-A

Classification:
Monoclonal

Concentration:
0.97 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q16655

Gene Symbols:
MLANA

Immunogen:
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
CL12863

Conjugate:
Unconjugated

Gene:
MLANA

Gene Alias:
A930034P04Rik; Antigen LB39-AA; antigen SK29-AA; MART1; MART-1; melan-A; melanoma antigen recognized by T-cells 1; melanoma associated antigen recognized by T-cells 1; MLANA; Protein Melan-A

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2315

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1