PIMA546545

TSPO Monoclonal Antibody (CL13358), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546545-Each-of-1 In Stock ₹ 36,705.24

PIMA546545 - Each of 1

₹ 36,705.24

In Stock

Quantity

1

Base Price: ₹ 36,705.24

GST (18%): ₹ 6,606.943

Total Price: ₹ 43,312.183

Antigen

TSPO

Classification

Monoclonal

Concentration

0.97 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P30536

Gene Symbols

Tspo

Immunogen

Synthetic Peptide

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

CL13358

Conjugate

Unconjugated

Gene

Tspo

Gene Alias

Benzodiazepin receptor (peripheral); benzodiazepine peripheral binding site; benzodiazepine receptor, peripheral; BPBS; BZRP; DBI; IBP; isoquinoline-binding protein; MBR; mDRC; mitochondrial benzodiazepine receptor; OTTHUMP00000028891; PBR; PBS; peripheral-type benzodiazepine receptor; pk18; PKBS; PTBR; Ptbzr; PTBZR02; RATPTBZR02; translocator protein; translocator protein (18kDa); TSPO; Tspo1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

706

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • Mitochondrial peripheral-type benzodiazepine receptor (PBR) is an indispensable element of the steroidogenic machinery, where it mediates the delivery of cholesterol to the inner mitochondrial side chain cleavage cytochrome P-450 upon ligand activation
  • PBR is composed of three subunits, an isoquinoline binding site, a voltage-dependent anion channel and an adenine nucleotide carrier
  • PBR is genetically conserved from bacteria to humans and in humans is widely expressed in peripheral organs, whereas in the brain, it is sparse and located mainly in glial cells
  • Peroxisome proliferator perfluordecanoic acid (PFDA) inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria and subsequent steroid formation
  • A cytoplasmic protein, PRAX-1 ( peripheral benzodiazepine receptor-associated protein 1), is found to specifically interact with PBR.

Compare Similar Items

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Img

Thermo Scientific

PIMA546545

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Antigen:
TSPO

Classification:
Monoclonal

Concentration:
0.97 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P30536

Gene Symbols:
Tspo

Immunogen:
Synthetic Peptide

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
CL13358

Conjugate:
Unconjugated

Gene:
Tspo

Gene Alias:
Benzodiazepin receptor (peripheral); benzodiazepine peripheral binding site; benzodiazepine receptor, peripheral; BPBS; BZRP; DBI; IBP; isoquinoline-binding protein; MBR; mDRC; mitochondrial benzodiazepine receptor; OTTHUMP00000028891; PBR; PBS; peripheral-type benzodiazepine receptor; pk18; PKBS; PTBR; Ptbzr; PTBZR02; RATPTBZR02; translocator protein; translocator protein (18kDa); TSPO; Tspo1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
706

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA546547

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Antigen:
Bub1

Classification:
Monoclonal

Concentration:
1.1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O08901, O43683

Gene Symbols:
BUB1

Immunogen:
Fusion protein, corresponding to amino acids 281-419 of Human Bub 1

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
14H5

Conjugate:
FITC

Gene:
BUB1

Gene Alias:
Aamp; Aamp-rs; AL022991; angio associated migratory cell protein; angio-associated migratory cell protein; angio-associated migratory protein; angio-associated, migratory cell protein; AU040907; BUB1; BUB1 budding uninhibited by benzimidazoles 1 homolog; BUB1 mitotic checkpoint serine/threonine kinase; BUB1, mitotic checkpoint serine/threonine kinase; BUB1A; BUB1L; budding uninhibited by benzimidazoles 1 homolog; budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae); C80208; D2Xrf87; hBUB1; mBUB1; mitotic checkpoint serine/threonine-protein kinase BUB1; mitotic spindle checkpoint kinase; putative serine/threonine-protein kinase

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12235, 699

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Isotype:
IgG1

Img

Thermo Scientific

PIMA546548

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Antigen:
CENPE

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q02224

Gene Symbols:
CENPE

Immunogen:
Recombinant full length human CENP-E protein

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation

Clone:
1H12

Conjugate:
Unconjugated

Gene:
CENPE

Gene Alias:
312kDa; AU019344; BC049989; C530022J18; Cenpe; CENP-E; centromere autoantigen E; Centromere autoantigen E (312kD); centromere protein E; centromere protein E, 312kDa; centromere-associated protein E; centromeric protein E; KIF10; kinesin 10; kinesin family member 10; kinesin superfamily protein 10; Kinesin-7; Kinesin-related protein CENPE; MCPH13; Motor domain of KIF10; N-7 kinesin; PPP1R61; protein phosphatase 1, regulatory subunit 61

Host Species:
Mouse

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1062

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA546549

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Antigen:
SMN1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P97801, Q16637

Gene Symbols:
SMN1

Immunogen:
Purified human recombinant His 6 tagged-SMN protein

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, X. laevis

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
2B1

Conjugate:
Unconjugated

Gene:
SMN1

Gene Alias:
AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20595, 6606

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1