PIMA546600

Cas9 Monoclonal Antibody (7A9-3A3), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546600-Each-of-1 In Stock ₹ 31,400.52

PIMA546600 - Each of 1

₹ 31,400.52

In Stock

Quantity

1

Base Price: ₹ 31,400.52

GST (18%): ₹ 5,652.094

Total Price: ₹ 37,052.614

Antigen

Cas9

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Target Species

Bacteria

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

7A9-3A3

Conjugate

Biotin

Gene Alias

cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen

This antibody was raised against a recombinant protein within the N-terminal region of Streptococcus pyogene Cas9

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

Related Products

Img

Thermo Scientific

PIMA546568

--

Img

Thermo Scientific

PIMA547059

--

Img

Thermo Scientific

PIMA546569

--

Img

Thermo Scientific

PIMA547064

--

Img

Thermo Scientific

PIMA547057

--

Img

Thermo Scientific

PIMA546923

--

Img

Thermo Scientific

PIMA546924

--

Img

Thermo Scientific

PIMA546975

--

Description

  • Cas9 is an RNA-guided DNA endonuclease enzyme associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) adaptive immunity system in bacteria and genetic engineering
  • The system is unique and flexible due to its dependence on RNA as the element that targets the nuclease to a desired DNA sequence
  • It can be used to induce indel mutations, specific sequence replacements/insertions, and large deletions or genomic rearrangements at any desired location in the genome
  • In addition, Cas9 can also be used to mediate upregulation of specific endogenous genes or to alter histone modifications or DNA methylation
  • Cas9 may be derived from Streptococcus pyogenes (SpCas9) or Staphylococcus aureus (SaCas9)
  • SaCas9 has a number of properties that make it advantageous for genome editing, including its small size, high efficiency, nickase activity, and apparent specificity
  • SaCas9 principally recognizes an NNGRRT protospacer adjacent motif (PAM) and cleaves target DNA at rates comparable to SpCas9 with an ideal spacer lengths of 24 to 20 nucleotides
  • In comparison to SpCas9, SaCas9 is smaller (1368 AA versus 1053 AA) and generates indels at a comparable rate when directed against target DNA with the mutually permissive NGGRRT PAM
  • This makes it the preferred enzyme for all-in-one delivery of Cas9 and multiple gRNA expression cassettes with Adeno-associated vectors.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA546600

--


Antigen:
Cas9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Bacteria

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
7A9-3A3

Conjugate:
Biotin

Gene Alias:
cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen:
This antibody was raised against a recombinant protein within the N-terminal region of Streptococcus pyogene Cas9

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA546602

--


Antigen:
Lamin A/C

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry

Clone:
JOL3

Conjugate:
FITC

Gene Alias:
70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg

Immunogen:
Recombinant bacterially expressed human lamin A

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Isotype:
IgG1

Img

Thermo Scientific

PIMA546606

--


Antigen:
E. coli serotype O157

Classification:
Monoclonal

Concentration:
0.38 mg/mL

Formulation:
PBS with 0.1% sodium azide

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Bacteria

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Clone:
9.88

Conjugate:
Unconjugated

Gene Alias:
Escherichia coli

Immunogen:
Tissue, cells or virus corresponding to Escherichia coli E. coli. A crude sonicate of E. coli O157

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgM κ

Img

Thermo Scientific

PIMA546607

--


Antigen:
Klebsiella aerogenes

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Target Species:
Bacteria

Form:
Liquid

Applications:
ELISA

Clone:
57/82

Conjugate:
Unconjugated

Gene Alias:
Enterobacter aerogenes

Immunogen:
A crude sonicate of Klebsiella aerogenes

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 λ