PIMA546646

IGF1R (CD221) Recombinant Rabbit Monoclonal Antibody (012), PE, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546646-Each-of-1 In Stock ₹ 36,705.24

PIMA546646 - Each of 1

₹ 36,705.24

In Stock

Quantity

1

Base Price: ₹ 36,705.24

GST (18%): ₹ 6,606.943

Total Price: ₹ 43,312.183

Antigen

IGF1R (CD221)

Classification

Recombinant Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.

P08069

Gene Symbols

IGF1R

Immunogen

Recombinant protein ecoding Human IGF1R (CD221) (Met1-Asn932).

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry

Clone

012

Conjugate

PE

Gene

IGF1R

Gene Alias

A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3480

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human IGF1R (CD221) (Met1-Asn932) and conjugated with PE under optimum conditions, the unreacted PE was removed
  • Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity
  • Protected from prolonged exposure to light
  • Do not freeze! Sodium azide is toxic to cells and should be disposed of properly
  • Flush with large volumes of water during disposal
  • IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2
  • IGFR has been implicated in a variety of cancers
  • The protein is a tetramer consisting of two alpha, and two beta subunits
  • The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2
  • Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136
  • The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA546646

--


Antigen:
IGF1R (CD221)

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.:
P08069

Gene Symbols:
IGF1R

Immunogen:
Recombinant protein ecoding Human IGF1R (CD221) (Met1-Asn932).

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
012

Conjugate:
PE

Gene:
IGF1R

Gene Alias:
A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3480

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA546647

--


Antigen:
CD25

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.5% BSA and 0.03% ProClin 300

Gene Accession No.:
P01589

Gene Symbols:
IL2RA

Immunogen:
Recombinant protein ecoding Human CD25 (Met1-Cys213).

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
216

Conjugate:
APC

Gene:
IL2RA

Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3559

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA546649

--


Antigen:
CD25

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.5% BSA and 0.03% ProClin 300

Gene Accession No.:
P01589

Gene Symbols:
IL2RA

Immunogen:
Recombinant protein ecoding Human CD25 (Met1-Cys213).

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
216

Conjugate:
FITC

Gene:
IL2RA

Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3559

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA546650

--


Antigen:
CD25

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.:
P01589

Gene Symbols:
IL2RA

Immunogen:
Recombinant protein ecoding Human CD25 (Met1-Cys213).

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
216

Conjugate:
PE

Gene:
IL2RA

Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3559

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid