PIMA546960

iNOS Recombinant Rabbit Monoclonal Antibody (HL1213), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546960-Each-of-1 In Stock ₹ 38,758.68

PIMA546960 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

iNOS

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P29477, Q06518

Gene Symbols

Nos2

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse iNOS. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

HL1213

Conjugate

Unconjugated

Gene

Nos2

Gene Alias

Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18126, 24599

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
  • Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
  • NO production is mediated by members of the nitric oxide synthase (NOS) family
  • iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
  • NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
  • Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
  • All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
  • iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
  • Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
  • Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
  • After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
  • Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
  • Diseases associated with iNOS dysfunction include achalasia and impotence.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA546960

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Antigen:
iNOS

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P29477, Q06518

Gene Symbols:
Nos2

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse iNOS. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL1213

Conjugate:
Unconjugated

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18126, 24599

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA546964

--


Antigen:
RRM1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P07742, P23921

Gene Symbols:
RRM1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human RRM1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Feline, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL1231

Conjugate:
Unconjugated

Gene:
RRM1

Gene Alias:
cb396; cb838; CHUNP6866; hypothetical protein; R RRM 1; r1; RI RI RR 1; Ribonucleoside-diphosphate reductase large subunit; ribonucleoside-diphosphate reductase M1 chain; ribonucleoside-diphosphate reductase subunit M1; ribonucleotide reductase catalytic subunit M1; ribonucleotide reductase large subunit; ribonucleotide reductase M1; ribonucleotide reductase M1 L homeolog; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase M1 S homeolog; ribonucleotide reductase protein R1 class I; ribonucleotide reductase subunit M1; ribonucleotide reductase, R1 subunit; RIR 1; RIR1; RnrM1; RR1; Rrm1; rrm1 protein; rrm1.L; rrm1.S; sb:cb548; wu:fb39b07; wu:fi14b02; wu:fk95f07; XELAEV_18013932mg; XRRM1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
101097343, 20133, 476823, 6240, 685579

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA546965

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Antigen:
Dicer

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q8R418, Q9UPY3

Gene Symbols:
DICER1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Dicer. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Feline, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL1232

Conjugate:
Unconjugated

Gene:
DICER1

Gene Alias:
1110006F08Rik; D12Ertd7e; DCR; DCR1; DCR-1; Dicer; dicer 1 ribonuclease III; dicer 1, double-stranded RNA-specific endoribonuclease; dicer 1, ribonuclease III; dicer 1, ribonuclease type III; Dicer1; Dicer1, Dcr-1 homolog; Dicer1e; double-strand-specific ribonuclease mDCR-1; endoribonuclease Dicer; Helicase MOI; helicase with RNAse motif; helicase-moi; HERNA; K12H4.8-LIKE; KIAA0928; mKIAA0928; MNG1; RMSE2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
192119, 23405, 299284, 480426

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA546966

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Antigen:
HOXC10

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9NYD6

Gene Symbols:
HOXC10

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Homeobox C10 The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
HL1234

Conjugate:
Unconjugated

Gene:
HOXC10

Gene Alias:
AI506621; homeo box C10; homeobox C10; homeobox protein Hox-3.6; Homeobox protein Hox-3I; homeobox protein Hox-C10; homeoprotein C10; Hox3.5 homeobox; Hox-3.6; HOX3I; HOXC10; Hoxc-10

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3226

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid