PIMA547043
SARS-CoV-2 NSP1 Recombinant Rabbit Monoclonal Antibody (HL1435), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547043-Each-of-1 | In Stock | ₹ 38,758.68 |
PIMA547043 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
SARS-CoV-2 NSP1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
HL1435
Conjugate
Unconjugated
Gene Alias
COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) nsp1. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- Inhibits host translation by interacting with the 40S ribosomal subunit (PubMed:32680882)
- Nsp1 C terminus binds to and obstructs ribosomal mRNA entry tunnel (PubMed:32680882)
- Thereby inhibits antiviral response triggered by innate immunity or interferons (PubMed:32680882)
- The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation
- Viral mRNAs are not susceptible to nsp1-mediated endonucleolytic RNA cleavage thanks to the presence of a 5'-end leader sequence and are therefore protected from degradation
- By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response.
Compare Similar Items
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Antigen: SARS-CoV-2 NSP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: HL1435
Conjugate: Unconjugated
Gene Alias: COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) nsp1. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SARS-CoV-2 NSP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1435
Conjugate:
Unconjugated
Gene Alias:
COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) nsp1. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SARS-CoV-2 Envelope
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: HL1443
Conjugate: Unconjugated
Gene Alias: COVID19 Envelope Protein
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) Envelope. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SARS-CoV-2 Envelope
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
HL1443
Conjugate:
Unconjugated
Gene Alias:
COVID19 Envelope Protein
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) Envelope. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SARS-CoV-2 NSP15
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: HL1445
Conjugate: Unconjugated
Gene Alias: COVID-19 Envelope; SARS-CoV-2; SARS-CoV-2 Envelope
Immunogen: Recombinant protein encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) nsp15. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SARS-CoV-2 NSP15
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1445
Conjugate:
Unconjugated
Gene Alias:
COVID-19 Envelope; SARS-CoV-2; SARS-CoV-2 Envelope
Immunogen:
Recombinant protein encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) nsp15. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MURF1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: HL1450
Conjugate: Unconjugated
Gene Alias: E3 ubiquitin-protein ligase TRIM63; FLJ32380; IRF; iris ring finger protein; Murf; MURF 1; MuRF1; MuRF-1; MURF2; muscle ring finger protein 1; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; OTTHUMP00000008701; RF1; ring finger protein 28; RING-type E3 ubiquitin transferase TRIM63; RNF 28; RNF28; SMRZ; striated muscle RING zinc finger protein; TRIM 63; Trim63; tripartite motif containing 63; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif protein 63; tripartite motif-containing 63; tripartite motif-containing protein 63
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MURF1. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MURF1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
HL1450
Conjugate:
Unconjugated
Gene Alias:
E3 ubiquitin-protein ligase TRIM63; FLJ32380; IRF; iris ring finger protein; Murf; MURF 1; MuRF1; MuRF-1; MURF2; muscle ring finger protein 1; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; OTTHUMP00000008701; RF1; ring finger protein 28; RING-type E3 ubiquitin transferase TRIM63; RNF 28; RNF28; SMRZ; striated muscle RING zinc finger protein; TRIM 63; Trim63; tripartite motif containing 63; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif protein 63; tripartite motif-containing 63; tripartite motif-containing protein 63
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MURF1. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid