PIMA547236

Apolipoprotein B Recombinant Rabbit Monoclonal Antibody (HL1960), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547236-Each-of-1 In Stock ₹ 38,758.68

PIMA547236 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

Apolipoprotein B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P04114

Gene Symbols

APOB

Immunogen

Synthetic peptide of human Apolipoprotein B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone

HL1960

Conjugate

Unconjugated

Gene

APOB

Gene Alias

Aa1064; Ac1-060; AI315052; Apo B100; Apo B-100; Apo B-48; APOB; apo-B; ApoB 100; ApoB 48; ApoB-100; apob-48; apolipo b; apolipoprotein B; apolipoprotein B (including Ag(x) antigen); Apolipoprotein B 100; Apolipoprotein B 48; apolipoprotein B PI; Apolipoprotein B100; apolipoprotein B-100; apolipoprotein B46; apolipoprotein B47; apolipoprotein B48; Apolipoprotein B-48; apolipoprotein B49; FLDB; LDLCQ4; LOX-1; mCG_129875; MGC176318; Ox-LDL receptor 1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

338

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • Apolipoprotein B (apo B) in human plasma is a major protein of low density lipoproteins (LDL) with a molecular mass of approximately 260-500 kDa
  • Apolipoprotein B binds to specific receptors on cell membranes and is involved in removal of LDL and very low density lipoprotein (VLDL) cholesterol from circulation
  • Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood
  • LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearance of cholesterol from the circulation
  • In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36
  • Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described
  • MDA-oxidized LDL appear to be different from LDL oxidized by other means
  • Apolipoprotein B is mostly synthesized in the liver, and is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a)
  • Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis
  • Normal plasma apolipoprotein B levels are around 800mg/L
  • Apolipoprotein B occurs in plasma as two main isoforms, apoB-48 and apoB-100
  • The intestinal and the hepatic forms of Apolipoprotein B are encoded by a single gene from a single, very long mRNA
  • The two isoforms share a common N-terminal sequence
  • The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination
  • Mutations in the Apolipoprotein B gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective Apolipoprotein B, diseases affecting plasma cholesterol and Apolipoprotein B levels.

Compare Similar Items

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Img

Thermo Scientific

PIMA547236

--


Antigen:
Apolipoprotein B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P04114

Gene Symbols:
APOB

Immunogen:
Synthetic peptide of human Apolipoprotein B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL1960

Conjugate:
Unconjugated

Gene:
APOB

Gene Alias:
Aa1064; Ac1-060; AI315052; Apo B100; Apo B-100; Apo B-48; APOB; apo-B; ApoB 100; ApoB 48; ApoB-100; apob-48; apolipo b; apolipoprotein B; apolipoprotein B (including Ag(x) antigen); Apolipoprotein B 100; Apolipoprotein B 48; apolipoprotein B PI; Apolipoprotein B100; apolipoprotein B-100; apolipoprotein B46; apolipoprotein B47; apolipoprotein B48; Apolipoprotein B-48; apolipoprotein B49; FLDB; LDLCQ4; LOX-1; mCG_129875; MGC176318; Ox-LDL receptor 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
338

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547237

--


Antigen:
Apolipoprotein B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P04114

Gene Symbols:
APOB

Immunogen:
Recombinant fragment of human Apolipoprotein B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL1962

Conjugate:
Unconjugated

Gene:
APOB

Gene Alias:
Aa1064; Ac1-060; AI315052; Apo B100; Apo B-100; Apo B-48; APOB; apo-B; ApoB 100; ApoB 48; ApoB-100; apob-48; apolipo b; apolipoprotein B; apolipoprotein B (including Ag(x) antigen); Apolipoprotein B 100; Apolipoprotein B 48; apolipoprotein B PI; Apolipoprotein B100; apolipoprotein B-100; apolipoprotein B46; apolipoprotein B47; apolipoprotein B48; Apolipoprotein B-48; apolipoprotein B49; FLDB; LDLCQ4; LOX-1; mCG_129875; MGC176318; Ox-LDL receptor 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
338

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547239

--


Antigen:
PCNA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P04961, P12004, P17918, Q9PTP1

Gene Symbols:
Pcna

Immunogen:
Recombinant fragment of human PCNA

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Feline, Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
HL1965

Conjugate:
Unconjugated

Gene:
Pcna

Gene Alias:
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
101080704, 18538, 25737, 30678, 477166, 5111

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547240

--


Antigen:
PCNA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P12004

Gene Symbols:
Pcna

Immunogen:
Recombinant fragment of human PCNA

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
HL1966

Conjugate:
Unconjugated

Gene:
Pcna

Gene Alias:
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
477166, 5111

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid