PIMA547336

Tyrosine Hydroxylase Monoclonal Antibody (4H2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547336-Each-of-1 In Stock ₹ 1,43,740.80

PIMA547336 - Each of 1

₹ 1,43,740.80

In Stock

Quantity

1

Base Price: ₹ 1,43,740.80

GST (18%): ₹ 25,873.344

Total Price: ₹ 1,69,614.144

Antigen

Tyrosine Hydroxylase

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.

P04177, P07101, P24529

Gene Symbols

TH

Immunogen

Full length human TH as expressed in and purified from E. coli

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone

4H2

Conjugate

Unconjugated

Gene

TH

Gene Alias

dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

21823, 25085, 7054

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine
  • In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4)
  • BH4 binds to the TH catalytic domain, resulting in enzymatic activity
  • Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated
  • These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains
  • TH is also responsible for the conversion of L-tyrosine to L-dopa
  • TH plays a key role in the physiology of adrenergic neurons
  • The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA547336

--


Antigen:
Tyrosine Hydroxylase

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P04177, P07101, P24529

Gene Symbols:
TH

Immunogen:
Full length human TH as expressed in and purified from E. coli

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
4H2

Conjugate:
Unconjugated

Gene:
TH

Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
21823, 25085, 7054

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547339

--


Antigen:
Calbindin D28K

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P04467, P05937, P07171, P12658

Gene Symbols:
CALB1

Immunogen:
Full-length recombinant human calbindin protein expressed in and purified from E. coli.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
4H7

Conjugate:
Unconjugated

Gene:
CALB1

Gene Alias:
Brain-2; CAB27; CaBP28K; Calb; CALB1; Calb-1; Calbindin; calbindin 1; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin D28; calbindin-28K; calbindin-D (28k); CalbindinD28K; CB; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; RTVL-H protein; spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100153645, 12307, 539930, 793, 83839

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547340

--


Antigen:
Aurora A/B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
O14965, O55099, O70126, P59241, P97477, Q96GD4

Gene Symbols:
AURKA, AURKB

Immunogen:
Full length recombinant human Aurora A protein expressed in and purified from E. coli.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Canine, Equine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5A12

Conjugate:
Unconjugated

Gene:
AURKA

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100050161, 100073050, 114592, 20877, 20878, 261730, 479492, 485940, 6790, 9212

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547341

--


Antigen:
mCherry

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Full length recombinant mCherry protein expressed in and purified from E. coli

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
5A6

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
mCherry

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid