PIMA547343

Tau Monoclonal Antibody (5B10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547343-Each-of-1 In Stock ₹ 1,43,740.80

PIMA547343 - Each of 1

₹ 1,43,740.80

In Stock

Quantity

1

Base Price: ₹ 1,43,740.80

GST (18%): ₹ 25,873.344

Total Price: ₹ 1,69,614.144

Antigen

Tau

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.

P10636, P10637, P19332

Gene Symbols

MAPT

Immunogen

Recombinant full length 441 amino acid human tau

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot

Clone

5B10

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

17762, 29477, 4137

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

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Img

Thermo Scientific

PIMA547343

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Antigen:
Tau

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
MAPT

Immunogen:
Recombinant full length 441 amino acid human tau

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
5B10

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 29477, 4137

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547344

--


Antigen:
GFAP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P03995, P14136, P47819, Q28115

Gene Symbols:
GFAP

Immunogen:
Purified porcine spinal cord GFAP

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
5C10

Conjugate:
Unconjugated

Gene:
GFAP

Gene Alias:
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100033970, 14580, 24387, 2670, 281189, 396562

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547345

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Antigen:
Galectin 3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P08699, P16110, P17931

Gene Symbols:
LGALS3

Immunogen:
Full length recombinant human galectin 3 expressed in and purified from E. coli.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5C21

Conjugate:
Unconjugated

Gene:
LGALS3

Gene Alias:
35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
16854, 3958, 83781

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547347

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Antigen:
Ki-67

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
E9PVX6

Gene Symbols:
Mki67

Immunogen:
Recombinant construct containing amino acids 956-1322 of the mouse sequence expressed in and purified from E. coli.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5F86

Conjugate:
Unconjugated

Gene:
Mki67

Gene Alias:
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
17345, 291234

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid