PIMA547414

Aurora B Monoclonal Antibody (3F11), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547414-Each-of-1 In Stock ₹ 41,967.18

PIMA547414 - Each of 1

₹ 41,967.18

In Stock

Quantity

1

Base Price: ₹ 41,967.18

GST (18%): ₹ 7,554.092

Total Price: ₹ 49,521.272

Antigen

Aurora B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.

O70126, Q96GD4

Gene Symbols

AURKB

Immunogen

Full length recombinant human aurora B protein expressed in and purified from E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Canine, Equine, Human, Mouse

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

3F11

Conjugate

Unconjugated

Gene

AURKB

Gene Alias

Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

100073050, 20877, 479492, 9212

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • The Aurora kinases associate with microtubules during chromosome movement and segregation
  • AURKB (Aurora B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers
  • This complex functions in chromosome alignment and separation, histone modification, and cytokinesis
  • CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB
  • Two CPCs exist during mitosis: one containing all four members and another consisting of INCENP and AurB
  • Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3
  • AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples
  • Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.

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Img

Thermo Scientific

PIMA547414

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Antigen:
Aurora B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
O70126, Q96GD4

Gene Symbols:
AURKB

Immunogen:
Full length recombinant human aurora B protein expressed in and purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Equine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3F11

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100073050, 20877, 479492, 9212

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547416

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Antigen:
14-3-3 eta

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P68509, P68510, P68511, Q04917

Gene Symbols:
YWHAH

Immunogen:
Full length human recombinant 14-3-3 (eta) protein expressed in and purified from E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3G12

Conjugate:
Unconjugated

Gene:
YWHAH

Gene Alias:
14-3-3 eta; 14-3-3 protein eta; 14-3-3 protein eta-subtype; 14-3-3e; 1433F; fb93e02; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; wu:fb51h04; wu:fb93e02; YWHA1; YWHA114-3-3 eta; ywhag; YWHAH; zgc:63883; zgc:63883 protein

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100155504, 100687866, 22629, 25576, 282126, 7533

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547417

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Antigen:
Calretinin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P22676, P47728, Q08331

Gene Symbols:
CALB2

Immunogen:
Full-length recombinant human protein expressed in and purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
3G9

Conjugate:
Unconjugated

Gene:
CALB2

Gene Alias:
29 kDa calbindin; 29kD calretinin; 29kDa calbindin; CAB29; CAL2; Calb2; calbindin 2; calbindin 2, (29kD, calretinin); calbindin 2, 29kDa; calbindin D29K; calretinin; CR; testicular secretory protein Li 8

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
117059, 12308, 794

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547418

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Antigen:
Aurora A/B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
O14965, O55099, O70126, P59241, P97477, Q96GD4

Gene Symbols:
AURKA, AURKB

Immunogen:
Full length recombinant human Aurora A protein expressed in and purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3H1

Conjugate:
Unconjugated

Gene:
AURKA

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
114592, 20877, 20878, 261730, 6790, 9212

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid