PIMA547435

Tyrosine Hydroxylase Monoclonal Antibody (4H2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547435-Each-of-1 In Stock ₹ 41,967.18

PIMA547435 - Each of 1

₹ 41,967.18

In Stock

Quantity

1

Base Price: ₹ 41,967.18

GST (18%): ₹ 7,554.092

Total Price: ₹ 49,521.272

Antigen

Tyrosine Hydroxylase

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.

P04177, P07101, P24529

Gene Symbols

TH

Immunogen

Full length human TH as expressed in and purified from E. coli

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone

4H2

Conjugate

Unconjugated

Gene

TH

Gene Alias

dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

21823, 25085, 7054

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine
  • In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4)
  • BH4 binds to the TH catalytic domain, resulting in enzymatic activity
  • Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated
  • These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains
  • TH is also responsible for the conversion of L-tyrosine to L-dopa
  • TH plays a key role in the physiology of adrenergic neurons
  • The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA547435

--


Antigen:
Tyrosine Hydroxylase

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P04177, P07101, P24529

Gene Symbols:
TH

Immunogen:
Full length human TH as expressed in and purified from E. coli

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
4H2

Conjugate:
Unconjugated

Gene:
TH

Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
21823, 25085, 7054

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547436

--


Antigen:
DJ-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
Q5E946, Q99497

Gene Symbols:
Park7

Immunogen:
Full length recombinant human DJ1 expressed in and purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
4H4

Conjugate:
Unconjugated

Gene:
Park7

Gene Alias:
CAP1; Contraception-associated protein 1; CTA-215D11.1; dj1; DJ-1; DJ-1 protein; early onset 7; epididymis secretory sperm binding protein Li 67p; fertility protein SP22; FLJ27376; FLJ34360; FLJ92274; HEL-S-67p; hypothetical protein LOC449674; maillard deglycase; Oncogene DJ1; OTTHUMP00000001350; OTTHUMP00000001351; PARK7; PARK7 GENE; PARK7/DJ1; parkinson disease (autosomal recessive, early onset) 7; Parkinson disease 7; Parkinson disease protein 7; Parkinson disease protein 7 homolog; Parkinson disease protein 7 homolog; protein/nucleic acid deglycase DJ-1; parkinson protein 7; Parkinsonism associated deglycase; parkinsonism-associated deglycase; Protein CAP1; protein deglycase DJ-1; protein deglycase DJ-1zDJ-1; Protein DJ-1; protein DJ-1-like protein; protein DJ-1zDJ-1; Protein/nucleic acid deglycase DJ-1; RNA-binding protein regulatory subunit; SP22; zDJ-1; zgc:103725

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
11315, 511268

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547437

--


Antigen:
MAP2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P11137, P15146, P20357

Gene Symbols:
Map2

Immunogen:
Full length MAP2A/B purified from bovine spinal cord

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
4H5

Conjugate:
Unconjugated

Gene:
Map2

Gene Alias:
a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
17756, 25595, 281294, 4133

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547439

--


Antigen:
Aurora A/B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
O14965, O55099, O70126, P59241, P97477, Q96GD4

Gene Symbols:
AURKA, AURKB

Immunogen:
Full length recombinant human Aurora A protein expressed in and purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Equine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5A12

Conjugate:
Unconjugated

Gene:
AURKA

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100050161, 100073050, 114592, 20877, 20878, 261730, 479492, 485940, 6790, 9212

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid