PIMA547442
Tau Monoclonal Antibody (5B10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547442-Each-of-1 | In Stock | ₹ 43,507.26 |
PIMA547442 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,507.26
GST (18%): ₹ 7,831.307
Total Price: ₹ 51,338.567
Antigen
Tau
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
P10636, P10637, P19332
Gene Symbols
MAPT
Immunogen
Recombinant full length 441 amino acid human tau
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Western Blot
Clone
5B10
Conjugate
Unconjugated
Gene
MAPT
Gene Alias
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
17762, 29477, 4137
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Tau is a neuronal microtubule-associated protein found predominantly on axons
- The function of Tau is to promote tubulin polymerization and stabilize microtubules
- The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
- Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
- The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
- In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
- Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
- Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
- Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Compare Similar Items
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Antigen: Tau
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.: P10636, P10637, P19332
Gene Symbols: MAPT
Immunogen: Recombinant full length 441 amino acid human tau
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: 5B10
Conjugate: Unconjugated
Gene: MAPT
Gene Alias: AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 17762, 29477, 4137
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Tau
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.:
P10636, P10637, P19332
Gene Symbols:
MAPT
Immunogen:
Recombinant full length 441 amino acid human tau
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
5B10
Conjugate:
Unconjugated
Gene:
MAPT
Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
17762, 29477, 4137
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: GFAP
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.: P03995, P14136, P47819, Q28115
Gene Symbols: GFAP
Immunogen: Purified porcine spinal cord GFAP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Equine, Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 5C10
Conjugate: Unconjugated
Gene: GFAP
Gene Alias: 6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 100033970, 14580, 24387, 2670, 281189, 396562
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
GFAP
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.:
P03995, P14136, P47819, Q28115
Gene Symbols:
GFAP
Immunogen:
Purified porcine spinal cord GFAP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Equine, Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
5C10
Conjugate:
Unconjugated
Gene:
GFAP
Gene Alias:
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
100033970, 14580, 24387, 2670, 281189, 396562
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Galectin 3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.: P08699, P16110, P17931
Gene Symbols: LGALS3
Immunogen: Full length recombinant human galectin 3 expressed in and purified from E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 5C21
Conjugate: Unconjugated
Gene: LGALS3
Gene Alias: 35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 16854, 3958, 83781
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Galectin 3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.:
P08699, P16110, P17931
Gene Symbols:
LGALS3
Immunogen:
Full length recombinant human galectin 3 expressed in and purified from E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
5C21
Conjugate:
Unconjugated
Gene:
LGALS3
Gene Alias:
35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
16854, 3958, 83781
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MARCKS
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.: P29966
Gene Symbols: MARCKS
Immunogen: Full length human MARCKS expressed in and purified from E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 5F9
Conjugate: Unconjugated
Gene: MARCKS
Gene Alias: 80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 4082
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MARCKS
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.:
P29966
Gene Symbols:
MARCKS
Immunogen:
Full length human MARCKS expressed in and purified from E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
5F9
Conjugate:
Unconjugated
Gene:
MARCKS
Gene Alias:
80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
4082
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid