PIMA547452

LAMP1 Monoclonal Antibody (5H6), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547452-Each-of-1 In Stock ₹ 41,967.18

PIMA547452 - Each of 1

₹ 41,967.18

In Stock

Quantity

1

Base Price: ₹ 41,967.18

GST (18%): ₹ 7,554.092

Total Price: ₹ 49,521.272

Antigen

LAMP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.

P11279

Gene Symbols

LAMP1

Immunogen

Amino acids 32-350 of the human LAMP1 precursor sequence purified from E. coli

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot

Clone

5H6

Conjugate

Unconjugated

Gene

LAMP1

Gene Alias

120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3916

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • LAMP1 (CD107a, lysosome-associated membrane protein-1) together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane
  • LAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment and a short (11 amino acid) cytosolic tail
  • The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes
  • LAMP1 is a type 1 integral membrane protein that is transported from trans-Golgi network to endosomes and then lysosomes
  • Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboyxl-terminal tyrosine based motif (YXXI)
  • Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1, and this mutant protein then cycles between the plasma membrane and the endosome
  • Cell surface LAMP1 (and LAMP2) have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore, they are possibly involved in the adhesion of PBMC to the site of inflammation
  • Increased LAMP1 immunoreactivity is observed in neurons and glial cells surrounding senile plaques in Alzheimer’s Disease (AD) cases, and is localized in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution
  • LAMP1 is a good marker of mast cell activation.

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Img

Thermo Scientific

PIMA547452

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Antigen:
LAMP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P11279

Gene Symbols:
LAMP1

Immunogen:
Amino acids 32-350 of the human LAMP1 precursor sequence purified from E. coli

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
5H6

Conjugate:
Unconjugated

Gene:
LAMP1

Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3916

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547453

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Antigen:
EWSR1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
Q01844, Q61545

Gene Symbols:
EWSR1

Immunogen:
Full length human EWS expressed in and purified from <i>E. coli</i>.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Equine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5H7

Conjugate:
Unconjugated

Gene:
EWSR1

Gene Alias:
AC002059.7; bK984G1.4; Ewing sarcoma breakpoint region 1; Ewing sarcoma breakpoint region 1 protein; Ewing sarcoma homolog; Ewings sarcoma EWS-Fli1 (type 1) oncogene; Ews; EWS oncogene; EWS RNA binding protein 1; EWS RNA-binding protein 1; EWS RNA-binding protein variant 6; EWS-FLI1; Ewsh; EWSR1; RNA-binding protein EWS

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100034010, 14030, 2130, 289752, 609786

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547454

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Antigen:
Actin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P60708, P60709, P60710, P60711, P60712, P62736, P62737, P62738, P62739, P63258, P63259, P63260, P63261, P63267, P63268, P63269, P68032, P68033, P68035, P68133, P68134, P68136, P68137, P68138, Q3ZC07, Q5E9B5, Q6QAQ1

Gene Symbols:
Acta1, ACTA2, ACTB, ACTC1, ACTG1, ACTG2

Immunogen:
Actin preparation from bovine brain

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5J11

Conjugate:
Unconjugated

Gene:
ACTG1

Gene Alias:
0610041G09Rik; 5C actin; A; A4V404_DROME; AA959943; a-actin; AAT6; Ac5C; act; act 5C; ACT1_DROME; Act4; ACT-4; Act5; ACT-5; Act5c; Act-5C; Act5C-PA; Act5C-PB; Act5C-PC; Act5C-PD; Act5C-PE; acta; ACTA1; ACTA1 protein; acta1.S; acta2; Acta-2; ACTA3; ACTB; actb.L; ACTC; ACTC1; Actc-1; ACTE; Actg; ACTG1; Actg2; ACTGE; Actin; actin 5 C; actin 5c; actin A1; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin beta; actin gamma 1; actin gamma 2, smooth muscle; actin homolog; actin, alpha 1, skeletal muscle; actin, alpha 1, skeletal muscle S homeolog; actin, alpha 2, smooth muscle, aorta; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; actin, alpha skeletal muscle S homeolog; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; actin, alpha, vascul

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100033878, 100050139, 100057561, 100057678, 100062175, 100065454, 100152267, 100154254, 100520667, 11459, 11461, 11464, 11465, 11468, 11475, 25365, 280979, 281592, 281595, 287876, 29275, 29437, 397653, 404122, 414396, 515610, 533219, 58, 59, 60, 70, 71, 72, 733615, 81633, 81822

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA547455

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Antigen:
beta Synuclein

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P33567, Q16143, Q63754, Q91ZZ3

Gene Symbols:
SNCB

Immunogen:
C-terminal peptide of human beta-synuclein EPEGESYEDPPQEEYQEYEPEA coupled to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
6A10

Conjugate:
Unconjugated

Gene:
SNCB

Gene Alias:
AI838531; betaSYN; beta-synuclein; Phosphoneuroprotein 14; PNP 14; Sncb; synuclein beta; synuclein, beta

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100127169, 104069, 113893, 508421, 6620

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid