Herpes Simplex Virus Type 1/2 gD Monoclonal Antibody (0197), Invitrogen™

Description

• Specificity: HSV 1&2, specific for glycoprotein D
• Purified preparations consist of >90% pure mouse monoclonal antibody which has been purified from ascites fluid by protein A chromatography
• The final preparation is formulated to a protein concentration of 100 μg/mL in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide
• Each vial contains 1.0 mL
• This product contains no stabilizing proteins and should be stored at 4C until ready for use
• Working dilution must be determined by the user
• Suggested starting ranges are 1:10-1:50 for ICC/IF and 1:20-1:200
• for ELISA
• Members of the herpes virus family (Herpesviridae), Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2), are ubiquitously contagious to humans
• Also known as Human herpes virus 1 and 2 (HHV-1 and -2), respectively, HSV-1 strains produce cold sores, while HSV-2 produce most genital herpes
• They can be spread when an infected person is producing and shedding the virus
• The virion form of herpes viruses consists of a relatively large double-stranded, linear DNA genome encased within the capsid and wrapped in the viral envelope
• The different HSV strains carry over 70 open reading frames (ORFs)
• HSV has been linked to Alzheimer's disease.