PIMA547627

Phospho-Fascin (Ser39) Monoclonal Antibody (M315), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547627-Each-of-1 In Stock ₹ 44,961.78

PIMA547627 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Phospho-Fascin (Ser39)

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P85845, Q16658, Q61553

Gene Symbols

FSCN1

Immunogen

Clone (M315) was generated from a phospho-Fascin (Ser39) synthetic peptide (coupled to carrier peptide) corresponding to amino acids surrounding Ser39 in human Fascin. This sequence has high homology to the conserved site in rat and mouse Fascin, as well as to the conserved region in Fascin 2, but low homology to the conserved region in Fascin 3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

M315

Conjugate

Unconjugated

Gene

FSCN1

Gene Alias

55 kDa actin-bundling protein; 55kDa actin-bundling protein; AI663989; Fan1; fascin; fascin 1; fascin actin-bundling protein 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus); fascin homolog 1, actin-bundling protein; Fascin1; fascin-1; Fscn1; fscn1 {ECO:0000250; HSN; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; SNL; UniProtKB:Q16658}

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14086, 6624, 683788

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

Description

  • The antibody detects a 55 kDa* band corresponding to fascin on SDS-PAGE immunoblots of mouse C2C12 cells treated with Calyculin A
  • This band is not observed after lambda phosphatase treatment
  • Fascin organizes filamentous actin into bundles with a minimum of 4
  • 1:1 actin/fascin ratio
  • It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.

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Img

Thermo Scientific

PIMA547627

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Antigen:
Phospho-Fascin (Ser39)

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P85845, Q16658, Q61553

Gene Symbols:
FSCN1

Immunogen:
Clone (M315) was generated from a phospho-Fascin (Ser39) synthetic peptide (coupled to carrier peptide) corresponding to amino acids surrounding Ser39 in human Fascin. This sequence has high homology to the conserved site in rat and mouse Fascin, as well as to the conserved region in Fascin 2, but low homology to the conserved region in Fascin 3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
M315

Conjugate:
Unconjugated

Gene:
FSCN1

Gene Alias:
55 kDa actin-bundling protein; 55kDa actin-bundling protein; AI663989; Fan1; fascin; fascin 1; fascin actin-bundling protein 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus); fascin homolog 1, actin-bundling protein; Fascin1; fascin-1; Fscn1; fscn1 {ECO:0000250; HSN; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; SNL; UniProtKB:Q16658}

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14086, 6624, 683788

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547628

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Antigen:
Phospho-GSK3 alpha/beta (Tyr279, Tyr216)

Classification:
Monoclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P18265, P18266, P49840, P49841, Q2NL51, Q9WV60

Gene Symbols:
GSK3A, GSK3B

Immunogen:
Clone M132 was generated from a phospho-GSK-3beta (Tyr-216) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 216 of human GSK-3beta. This peptide sequence is also found in GSK-3alpha (Tyr-279) and is highly conserved in GSK-3 genes in rat and mouse.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M132

Conjugate:
Unconjugated

Gene:
GSK3B

Gene Alias:
2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; gsk-3-alpha; Gsk3b; GSK-3beta; GSK3beta isoform; serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2931, 2932, 50686, 56637, 606496, 84027

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547629

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Antigen:
Phospho-IkB alpha (Ser32, Ser36)

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 0.5% BSA and 0.05% sodium azide

Gene Accession No.:
P25963, Q63746, Q9Z1E3

Gene Symbols:
NFKBIA

Immunogen:
Clone 39A1413 was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 32 and 36 of human IkappaBalpha. This peptide sequence is highly conserved in mouse, rat, dog, cow, and pig IkappaBalpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Clone:
39A1413

Conjugate:
Unconjugated

Gene:
NFKBIA

Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18035, 25493, 4792

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

PIMA547631

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Antigen:
Phospho-NLRC4 (Ser533)

Classification:
Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
F1M649, Q3UP24, Q9NPP4

Gene Symbols:
Nlrc4

Immunogen:
Clone M549 was generated from a phospho-NLRC4 (Ser-533) synthetic peptide (coupled to carrier) corresponding to amino acids surrounding serine 533 in mouse NLRC4. This sequence has high homology to human and rat NLRC4, and is not homologous to sequences in other NLR family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M549

Conjugate:
Unconjugated

Gene:
Nlrc4

Gene Alias:
9530011P19Rik; AIFEC; CARD, LRR, and NACHT-containing protein; Card12; caspase recruitment domain family, member 12; caspase recruitment domain-containing protein 12; CLAN; Clan protein; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; ice protease-activating factor; ICE-protease activating factor; ipaf; NLR family CARD domain containing 4; NLR family CARD domain-containing protein 4; NLR family, CARD domain containing 4; NLRC4; NOD-like receptor C4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4; UNQ6189/PRO20215

Host Species:
Rat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
268973, 298784, 58484

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
__