PIMA547637
Phospho-STAT1 (Tyr701) Monoclonal Antibody (M135), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547637-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA547637 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
Phospho-STAT1 (Tyr701)
Classification
Monoclonal
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
P42224, P42225
Gene Symbols
STAT1
Immunogen
Clone (M135) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 701 of human Stat1. This peptide sequence has high homology to the conserved tyrosine site in rat and mouse stat1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Western Blot
Clone
M135
Conjugate
Unconjugated
Gene
STAT1
Gene Alias
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20846, 25124, 6772
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG1
Description
- The antibody detects 84 and 91 kDa* stat1 variants on SDS-PAGE immunoblots of human A431 treated with EGF, as well as Jurkat and A431 cells treated with pervanadate
- The antibody does not detect these variants in control cells
- STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
- STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
- STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
- Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
- The STAT1 gene is located on chromosome 2
- STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
- After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
- Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
- STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
- Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.
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Antigen: Phospho-STAT1 (Tyr701)
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P42224, P42225
Gene Symbols: STAT1
Immunogen: Clone (M135) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 701 of human Stat1. This peptide sequence has high homology to the conserved tyrosine site in rat and mouse stat1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Western Blot
Clone: M135
Conjugate: Unconjugated
Gene: STAT1
Gene Alias: 2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20846, 25124, 6772
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Phospho-STAT1 (Tyr701)
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P42224, P42225
Gene Symbols:
STAT1
Immunogen:
Clone (M135) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 701 of human Stat1. This peptide sequence has high homology to the conserved tyrosine site in rat and mouse stat1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Western Blot
Clone:
M135
Conjugate:
Unconjugated
Gene:
STAT1
Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20846, 25124, 6772
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: Phospho-delta Catenin (Tyr228)
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O60716, P30999
Gene Symbols: CTNND1
Immunogen: Clone M356 was generated from a phospho-delta1-Catenin (Tyr-228) synthetic peptide containing amino acid residues around tyrosine 228 of human delta1-Catenin. This peptide sequence is highly conserved in rat and mouse delta1-Catenin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: M356
Conjugate: Unconjugated
Gene: CTNND1
Gene Alias: AA409437; AU019353; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin delta 1; catenin delta-1; catenin src; catenin, delta 1; Catns; CTNND; Ctnnd1; hypothetical protein; Kiaa0384; mKIAA0384; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(CAS); p120(ctn); P120CAS; p120-catenin; P120CTN
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12388, 1500, 311163
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Phospho-delta Catenin (Tyr228)
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O60716, P30999
Gene Symbols:
CTNND1
Immunogen:
Clone M356 was generated from a phospho-delta1-Catenin (Tyr-228) synthetic peptide containing amino acid residues around tyrosine 228 of human delta1-Catenin. This peptide sequence is highly conserved in rat and mouse delta1-Catenin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
M356
Conjugate:
Unconjugated
Gene:
CTNND1
Gene Alias:
AA409437; AU019353; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin delta 1; catenin delta-1; catenin src; catenin, delta 1; Catns; CTNND; Ctnnd1; hypothetical protein; Kiaa0384; mKIAA0384; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(CAS); p120(ctn); P120CAS; p120-catenin; P120CTN
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12388, 1500, 311163
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: Phospho-Caveolin 1 (Tyr14)
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P41350, P49817, Q03135
Gene Symbols: CAV1
Immunogen: Clone M283 was generated from a phospho-Caveolin-1 (Tyr-14) synthetic peptide corresponding to amino acids surrounding tyrosine 14 in human Caveolin-1. This sequence has significant homology to the conserved site in rat and mouse Caveolin-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: M283
Conjugate: Unconjugated
Gene: CAV1
Gene Alias: BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12389, 25404, 857
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Phospho-Caveolin 1 (Tyr14)
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P41350, P49817, Q03135
Gene Symbols:
CAV1
Immunogen:
Clone M283 was generated from a phospho-Caveolin-1 (Tyr-14) synthetic peptide corresponding to amino acids surrounding tyrosine 14 in human Caveolin-1. This sequence has significant homology to the conserved site in rat and mouse Caveolin-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
M283
Conjugate:
Unconjugated
Gene:
CAV1
Gene Alias:
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12389, 25404, 857
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: Phospho-EGFR (Tyr1101)
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P00533, Q01279
Gene Symbols: EGFR
Immunogen: Clone (M199) was generated from a phospho-EGFR (Tyr1101) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr1101 of human EGFR (ErbB-1). This human EGFR sequence has high homology to rat and mouse EGFR and is not conserved in other ErbB family members. This site is Tyr1125 in the P00533-1 version of human EGFR.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: M199
Conjugate: Unconjugated
Gene: EGFR
Gene Alias: 2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 13649, 1956, 24329
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Phospho-EGFR (Tyr1101)
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P00533, Q01279
Gene Symbols:
EGFR
Immunogen:
Clone (M199) was generated from a phospho-EGFR (Tyr1101) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr1101 of human EGFR (ErbB-1). This human EGFR sequence has high homology to rat and mouse EGFR and is not conserved in other ErbB family members. This site is Tyr1125 in the P00533-1 version of human EGFR.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
M199
Conjugate:
Unconjugated
Gene:
EGFR
Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
13649, 1956, 24329
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1