PIMA547653

CD59 Monoclonal Antibody (M011), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547653-Each-of-1 In Stock ₹ 45,817.38

PIMA547653 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Antigen

CD59

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P13987

Gene Symbols

CD59

Immunogen

Clone M011 was generated from a proprietary antigen related to the mature form of human CD59 from the MDA-MB-231 breast carcinoma cell line.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

M011

Conjugate

Unconjugated

Gene

CD59

Gene Alias

16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

966

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

Description

  • Clone M011 detects 15-20 kDa* bands corresponding to CD59 on SDS-PAGE immunoblots of native human MDA-MB-231, A549, A431, and MCF7 cell lysates, as well as recombinant human CD59 protein
  • The antibody does not detect denatured CD59
  • The antibody can be used for multiple applications including ELISA capture, western blot, immunocytochemical labeling and immunoprecipitation
  • In addition, the antibody labels live, unfixed A549 and MeWo cells
  • CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC)
  • CD59 is the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade
  • CD59 also associates with C5b-8 complex and counteracts appropriate formation of cytolytic pore within the plasma membrane
  • Further, CD59 is a low-affinity ligand of human CD2, causes T cell costimulation, and is involved in lymphocyte signal transduction
  • CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation
  • Mutations in this gene cause CD59 deficiency, a disease involving hemolytic anemia, thrombosis, and cerebral infarction
  • Multiple alternatively spliced transcript variants of CD59 have been identified.

Compare Similar Items

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Img

Thermo Scientific

PIMA547653

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Antigen:
CD59

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P13987

Gene Symbols:
CD59

Immunogen:
Clone M011 was generated from a proprietary antigen related to the mature form of human CD59 from the MDA-MB-231 breast carcinoma cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M011

Conjugate:
Unconjugated

Gene:
CD59

Gene Alias:
16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
966

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547655

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Antigen:
CD63

Classification:
Monoclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P08962

Gene Symbols:
CD63

Immunogen:
Clone (M034) was generated from a proprietary antigen related to the native human CD63 expressed in MeWo melanoma cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M034

Conjugate:
Unconjugated

Gene:
CD63

Gene Alias:
C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
967

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547656

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Antigen:
CD99

Classification:
Monoclonal

Concentration:
∽0.5 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P14209, Q8VCN6

Gene Symbols:
CD99

Immunogen:
Clone M026 was generated from a proprietary antigen related to the extracellular region of human CD99 expressed in the MeWo melanoma cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M026

Conjugate:
Unconjugated

Gene:
CD99

Gene Alias:
1110061M03Rik; 12E7; 2410026K10Rik; antigen identified by monoclonal 12E7, Y homolog; antigen identified by monoclonal antibodies 12E7, F21 and O13; Cd99; CD99 antigen; CD99 molecule; cell surface antigen 12E7; cell surface antigen HBA-71; cell surface antigen O13; D4; E2 antigen; HBA71; MIC2; MIC2 (monoclonal antibody 12E7); MIC2X; MIC2Y; MSK5X; paired immunoglobin-like type 2 receptor-ligand; pilr-1; Pilrl; PILR-L; Protein MIC2; surface antigen MIC2; T-cell surface glycoprotein E2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4267, 652929, 673094

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547657

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Antigen:
CD147

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P35613

Gene Symbols:
BSG

Immunogen:
Clone (M036) was generated from a proprietary antigen related to the native human CD147 expressed in NCI-H1915 lung cancer cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M036

Conjugate:
Unconjugated

Gene:
BSG

Gene Alias:
5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
682

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG2a