PIMA547662
Cyclophilin B Monoclonal Antibody (M019), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547662-Each-of-1 | In Stock | ₹ 45,817.38 |
PIMA547662 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,817.38
GST (18%): ₹ 8,247.128
Total Price: ₹ 54,064.508
Antigen
Cyclophilin B
Classification
Monoclonal
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
P23284
Gene Symbols
PPIB
Immunogen
Clone M019 was generated from a proprietary antigen related to cyclophilin B from the MCF7 breast cancer cell line.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
M019
Conjugate
Unconjugated
Gene
PPIB
Gene Alias
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5479
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG1
Description
- Clone M019 detects a 20 kDa* band corresponding to the molecular mass of cyclophilin B on SDS-PAGE immunoblots of human LNCaP, MeWo, MCF7, and MDA-MB-231 cell lysates, as well as full length recombinant cyclophilin B, but does not detect recombinant cyclophilin A
- The antibody can be used for western blot, immunoprecipitation, protein ELISA, and immunocytochemistry
- Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
- Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP)
- Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation
- Thus, providing a possible mechanism of immunosuppression by CsA and FK506
- Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
- As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins.
Compare Similar Items
Show Difference
Antigen: Cyclophilin B
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P23284
Gene Symbols: PPIB
Immunogen: Clone M019 was generated from a proprietary antigen related to cyclophilin B from the MCF7 breast cancer cell line.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: M019
Conjugate: Unconjugated
Gene: PPIB
Gene Alias: AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5479
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Cyclophilin B
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P23284
Gene Symbols:
PPIB
Immunogen:
Clone M019 was generated from a proprietary antigen related to cyclophilin B from the MCF7 breast cancer cell line.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
M019
Conjugate:
Unconjugated
Gene:
PPIB
Gene Alias:
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5479
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: EB1
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q15691, Q61166, Q66HR2
Gene Symbols: Mapre1
Immunogen: Clone KT51 was generated from a GST fusion protein containing amino acids from the C-terminal region of mouse EB1. This sequence is highly conserved in human and rat EB1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: KT51
Conjugate: Unconjugated
Gene: Mapre1
Gene Alias: 5530600P05Rik; adenomatosis polyposis coli binding protein Eb1; adenomatous polyposis coli-binding protein EB1; AI462499; AI504412; APC-binding protein EB1; AW260097; BIM1p; D2Ertd459e; Eb1; end-binding protein 1; Mapre1; MGC117374; MGC129946; microtubule associated protein RP/EB family member 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein RP/EB family member 1-like protein; microtubule-associated protein, RP/EB family, member 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 114764, 13589, 22919
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a
Antigen:
EB1
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q15691, Q61166, Q66HR2
Gene Symbols:
Mapre1
Immunogen:
Clone KT51 was generated from a GST fusion protein containing amino acids from the C-terminal region of mouse EB1. This sequence is highly conserved in human and rat EB1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
KT51
Conjugate:
Unconjugated
Gene:
Mapre1
Gene Alias:
5530600P05Rik; adenomatosis polyposis coli binding protein Eb1; adenomatous polyposis coli-binding protein EB1; AI462499; AI504412; APC-binding protein EB1; AW260097; BIM1p; D2Ertd459e; Eb1; end-binding protein 1; Mapre1; MGC117374; MGC129946; microtubule associated protein RP/EB family member 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein RP/EB family member 1-like protein; microtubule-associated protein, RP/EB family, member 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
114764, 13589, 22919
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a
Antigen: MAPRE2
Classification: Monoclonal
Concentration: ∽1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q15555, Q3B8Q0, Q8R001
Gene Symbols: MAPRE2
Immunogen: Clone KT52 was generated from a GST fusion protein containing human EB2. This sequence is highly conserved in rat and mouse EB2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: KT52
Conjugate: Unconjugated
Gene: MAPRE2
Gene Alias: AI314113; APC-binding protein EB1; APC-binding protein EB2; C820009F03Rik; CSCSC2; D18Abb1e; EB1; EB2; End-binding protein 2; Mapre2; microtubule associated protein RP/EB family member 2; microtubule-associated protein RP/EB family member 2; microtubule-associated protein, RP/EB family, member 2; RP1; T-cell activation protein, EB1 family; T-cell activation protein, EB1 family, member 2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 10982, 212307, 679221
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2b
Antigen:
MAPRE2
Classification:
Monoclonal
Concentration:
∽1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q15555, Q3B8Q0, Q8R001
Gene Symbols:
MAPRE2
Immunogen:
Clone KT52 was generated from a GST fusion protein containing human EB2. This sequence is highly conserved in rat and mouse EB2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
KT52
Conjugate:
Unconjugated
Gene:
MAPRE2
Gene Alias:
AI314113; APC-binding protein EB1; APC-binding protein EB2; C820009F03Rik; CSCSC2; D18Abb1e; EB1; EB2; End-binding protein 2; Mapre2; microtubule associated protein RP/EB family member 2; microtubule-associated protein RP/EB family member 2; microtubule-associated protein, RP/EB family, member 2; RP1; T-cell activation protein, EB1 family; T-cell activation protein, EB1 family, member 2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
10982, 212307, 679221
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2b
Antigen: EphA2
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P29317
Gene Symbols: EPHA2
Immunogen: Clone (M049) was generated from a recombinant protein that included the extracellular region of human EphA2 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: M049
Conjugate: Unconjugated
Gene: EPHA2
Gene Alias: ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 1969
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
EphA2
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P29317
Gene Symbols:
EPHA2
Immunogen:
Clone (M049) was generated from a recombinant protein that included the extracellular region of human EphA2 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
M049
Conjugate:
Unconjugated
Gene:
EPHA2
Gene Alias:
ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
1969
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1