PIMA547670

JNK1 Monoclonal Antibody (M267), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547670-Each-of-1 In Stock ₹ 45,817.38

PIMA547670 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Antigen

JNK1

Classification

Monoclonal

Concentration

∽0.25 mg/mL

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P45983, P49185, Q91Y86

Gene Symbols

MAPK8

Immunogen

Clone M267 was generated from a recombinant protein corresponding to amino acid residues in the C-terminal region of human JNK1. This sequence has high homology to rat and mouse JNK1, and has homology to similar regions in JNK2 and JNK3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone

M267

Conjugate

Unconjugated

Gene

MAPK8

Gene Alias

AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK3; JNK3A; JNK-46; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAPK 10; MAPK 8; MAPK10; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8b; MK10; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; Phospho-JNK; PRKM10; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; zgc:112379

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

116554, 26419, 5599

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

Description

  • This antibody detects a 46 kDa* protein corresponding to the apparent molecular mass of JNK1 on SDS-PAGE immunoblots of human A431 and HeLa, as well as rat PC12 cells
  • MAPK8 (JNK1) is activated by the presence of misfolded proteins in the endoplasmic reticulum
  • It is also a crucial mediator of insulin resistance and obesity
  • It belongs to the MAPK superfamily of stress-activated protein kinases
  • MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus
  • JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
  • JNK pathways are activated by stress and inflammatory signals
  • JNK is expressed as ten different isoforms due to differential mRNA splicing
  • The predominant forms are JNK1 and JNK2.

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Img

Thermo Scientific

PIMA547670

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Antigen:
JNK1

Classification:
Monoclonal

Concentration:
∽0.25 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P45983, P49185, Q91Y86

Gene Symbols:
MAPK8

Immunogen:
Clone M267 was generated from a recombinant protein corresponding to amino acid residues in the C-terminal region of human JNK1. This sequence has high homology to rat and mouse JNK1, and has homology to similar regions in JNK2 and JNK3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
M267

Conjugate:
Unconjugated

Gene:
MAPK8

Gene Alias:
AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK3; JNK3A; JNK-46; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAPK 10; MAPK 8; MAPK10; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8b; MK10; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; Phospho-JNK; PRKM10; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; zgc:112379

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
116554, 26419, 5599

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547671

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Antigen:
Mitofilin

Classification:
Monoclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q16891

Gene Symbols:
IMMT

Immunogen:
Clone M027 was generated from a proprietary antigen related to human mitofilin expressed in the A431 epidermoid carcinoma cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M027

Conjugate:
Unconjugated

Gene:
IMMT

Gene Alias:
1700082C19Rik; cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; D830041H16Rik; EMBL:AAI05842.1, ECO:0000312; EMBL:AAI05842.1}; HMP; Immt; immt {ECO:0000312; IMMT antibody; inner membrane mitochondrial protein; inner membrane protein, mitochondrial; inner membrane protein, mitochondrial (mitofilin); MGC133830 protein; MIC60; MICOS complex subunit Mic60; MINOS2; mitochondrial inner membrane organizing system 2; mitochondrial inner membrane protein; mitochondrial inner membrane protein {ECO:0000250; Mitofilin; mitofilin {ECO:0000250; motor protein; P87; p87/89; p87/89 antibody; P89; PIG4; PIG52; proliferation-inducing gene 4; RGD:1310684}; UniProtKB:Q8CAQ8, ECO:0000312; UniProtKB:Q8CAQ8}

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10989

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547672

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Antigen:
CD298

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P54709

Gene Symbols:
ATP1B3

Immunogen:
Clone (M016) was generated from a proprietary antigen related to the native human Na+/K+ ATPase beta3 subunit expressed in A431 epidermoid carcinoma cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M016

Conjugate:
Unconjugated

Gene:
ATP1B3

Gene Alias:
AA409958; AI664000; Atp1b3; ATPase Na+/K+ transporting subunit beta 3; ATPase, Na+/K+ beta 3 polypeptide; ATPase, Na+/K+ transporting, beta 3 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 3; ATPB-3; AW212096; CD298; CD298 antigen; Na K-ATPase beta-3 subunit; Na+/K+ -ATPase beta 3 subunit; NKAB3S; Sodium Potassium ATPase; Sodium/potassium-dependent ATPase subunit beta-3; sodium/potassium-transporting ATPase subunit beta-3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
483

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547673

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Antigen:
CD298

Classification:
Monoclonal

Concentration:
∽0.25 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P54709

Gene Symbols:
ATP1B3

Immunogen:
Clone (M025) was generated from a proprietary antigen related to the native human Na+/K+ ATPase beta3 subunit expressed in MeWo melanoma cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M025

Conjugate:
Unconjugated

Gene:
ATP1B3

Gene Alias:
AA409958; AI664000; Atp1b3; ATPase Na+/K+ transporting subunit beta 3; ATPase, Na+/K+ beta 3 polypeptide; ATPase, Na+/K+ transporting, beta 3 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 3; ATPB-3; AW212096; CD298; CD298 antigen; Na K-ATPase beta-3 subunit; Na+/K+ -ATPase beta 3 subunit; NKAB3S; Sodium Potassium ATPase; Sodium/potassium-dependent ATPase subunit beta-3; sodium/potassium-transporting ATPase subunit beta-3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
483

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG2a