PIMA547699

Caspase 3 p17 Monoclonal Antibody (31A1067), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547699-Each-of-1 In Stock ₹ 39,272.04

PIMA547699 - Each of 1

₹ 39,272.04

In Stock

Quantity

1

Base Price: ₹ 39,272.04

GST (18%): ₹ 7,068.967

Total Price: ₹ 46,341.007

Antigen

Caspase 3 p17

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P42574, P55213, P70677

Gene Symbols

CASP3

Immunogen

Clone 31A1067 was developed against full-length recombinant human Caspase-3. The antibody recognizes an epitope in the large domain subunit (p17) of Caspase-3, and it will recognize pro Caspase-3 and the p17 cleavage fragment.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Western Blot

Clone

31A1067

Conjugate

Unconjugated

Gene

CASP3

Gene Alias

A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cleaved Caspase 3; Cpp32; CPP-32; CPP32beta; cysteine protease CPP32; IRP; LICE; mLdy; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12367, 25402, 836

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

Description

  • The antibody detects pro Caspase-3 at 32 kDa* and the large subunit of the cleaved form of Caspase-3 at 14-21 kDa
  • The antibody can be used for western blot, immunohistochemistry and immuno-electron microscopy
  • CASP3 (Caspase3 Apoptosis-Related Cysteine Protease), also known as YAMA, CPP32 or APOPAIN, is a caspase protein that interacts with caspase 8 and caspase 9
  • It is encoded by the CASP3 gene
  • The CASP3 protein is a member of the cysteine-aspartic acid protease (caspase) family
  • Tiso et al
  • (1996) used radiation hybrid mapping to localize the CPP32 gene to human chromosome 4q33-q35.1
  • Fernandes-Alnemri et al
  • (1994) found that overexpression of CPP32 in insect cells induced apoptosis
  • Coexpression of the 2 CPP32 subunits in insect cells also resulted in apoptosis
  • Tewari et al
  • (1995) showed that purified human ICE cleaved the Yama proenzyme into a proteolytically active form and that activated Yama cleaved PARP into the 85-kD apoptotic form.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA547699

--


Antigen:
Caspase 3 p17

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P42574, P55213, P70677

Gene Symbols:
CASP3

Immunogen:
Clone 31A1067 was developed against full-length recombinant human Caspase-3. The antibody recognizes an epitope in the large domain subunit (p17) of Caspase-3, and it will recognize pro Caspase-3 and the p17 cleavage fragment.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
31A1067

Conjugate:
Unconjugated

Gene:
CASP3

Gene Alias:
A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cleaved Caspase 3; Cpp32; CPP-32; CPP32beta; cysteine protease CPP32; IRP; LICE; mLdy; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12367, 25402, 836

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547700

--


Antigen:
Caspase 6

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P55212

Gene Symbols:
Casp6

Immunogen:
Clone (M378) was generated from a peptide containing amino acid residues in the C-terminal region of human Caspase-6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
M378

Conjugate:
Unconjugated

Gene:
Casp6

Gene Alias:
apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
839

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547701

--


Antigen:
c-Cbl

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P22681, P22682

Gene Symbols:
Cbl

Immunogen:
Clone (M159) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human c-Cbl. This sequence is highly conserved in rat and mouse c-Cbl.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M159

Conjugate:
Unconjugated

Gene:
Cbl

Gene Alias:
4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12402, 500985, 867

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547704

--


Antigen:
CD147

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P35613

Gene Symbols:
BSG

Immunogen:
Clone (M052) was generated from a proprietary antigen related to the native human CD147 expressed in NCI-H1915 lung cancer cell line.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
M052

Conjugate:
Unconjugated

Gene:
BSG

Gene Alias:
5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
682

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1