PIMA547713
EB1/EB2/EB3 Monoclonal Antibody (KT65), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547713-Each-of-1 | In Stock | ₹ 39,272.04 |
PIMA547713 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,272.04
GST (18%): ₹ 7,068.967
Total Price: ₹ 46,341.007
Antigen
EB1/EB2/EB3
Classification
Monoclonal
Concentration
Lot-Specific
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q15555, Q15691, Q3B8Q0, Q5XIT1, Q61166, Q66HR2, Q6PER3, Q8R001, Q9UPY8
Gene Symbols
Mapre1, Mapre2, Mapre3
Immunogen
Clone KT65 was generated from a GST fusion protein containing amino acids from the C-terminal region mouse EB1. This sequence is highly conserved in human and rat EB1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Clone
KT65
Conjugate
Unconjugated
Gene
Mapre2
Gene Alias
APC; Microtubule RP/EB
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100732, 10982, 114764, 13589, 212307, 22919, 22924, 298848, 679221
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG2a
Description
- The antibody detects a 30 kDa* protein corresponding to the molecular mass of EB1 on SDS-PAGE immunoblots of human HeLa, mouse brain, and rat PC12 cells
- The antibody also detects EB1 by immunocytochemistry in HeLa and A431 cells
- The antibody may weakly detect endogenous EB2 and EB3 in some cells and tissues
- The microtubule (MT) plus-end is a crucial site for the regulation of MT dynamics and interactions by several groups of plus-end tracking proteins (+TIPs)
- These +TIPs form comet-like accumulations at the plus ends of MTs to regulate MT dynamics and interactions with organelles and macromolecular complexes
- The +TIPs include diverse groups of proteins, such as motor and nonmotor proteins, MT polymerases and depolymerases as well as various regulatory and adaptor proteins
- The CLIP-associated protein (CLASP) family includes CLASP1 and CLASP2 proteins, which are expressed as long (alpha) and short (beta) isoforms
- Thse +TIPs conatin an N-terminal TOG domain, multiple TOG-like domains, and a basic and serine-rich motif (SxIP)
- The TOG domain facilitates interaction with tubulin dimers, while the SxIP motif promotes interaciton with EB1 and MTs
- A C-terminal domain is involved in interaction with CLIPs, as well as several other proteins
- CLASPs are MT stabilizing fators that localize to mitotic spindles, kinetochores, and the midbody
- CLASPs are important for cell division, and may regulate cell migration and neuronal growth cone motility.
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Antigen: EB1/EB2/EB3
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q15555, Q15691, Q3B8Q0, Q5XIT1, Q61166, Q66HR2, Q6PER3, Q8R001, Q9UPY8
Gene Symbols: Mapre1, Mapre2, Mapre3
Immunogen: Clone KT65 was generated from a GST fusion protein containing amino acids from the C-terminal region mouse EB1. This sequence is highly conserved in human and rat EB1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: KT65
Conjugate: Unconjugated
Gene: Mapre2
Gene Alias: APC; Microtubule RP/EB
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100732, 10982, 114764, 13589, 212307, 22919, 22924, 298848, 679221
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a
Antigen:
EB1/EB2/EB3
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q15555, Q15691, Q3B8Q0, Q5XIT1, Q61166, Q66HR2, Q6PER3, Q8R001, Q9UPY8
Gene Symbols:
Mapre1, Mapre2, Mapre3
Immunogen:
Clone KT65 was generated from a GST fusion protein containing amino acids from the C-terminal region mouse EB1. This sequence is highly conserved in human and rat EB1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
KT65
Conjugate:
Unconjugated
Gene:
Mapre2
Gene Alias:
APC; Microtubule RP/EB
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100732, 10982, 114764, 13589, 212307, 22919, 22924, 298848, 679221
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a
Antigen: MAPRE3
Classification: Monoclonal
Concentration: ∽1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols: MAPRE3
Immunogen: Clone KT53 was generated from a GST fusion protein containing human EB3. This sequence is highly conserved in rat and mouse EB3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: KT53
Conjugate: Unconjugated
Gene: MAPRE3
Gene Alias: AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100732, 22924, 298848
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a
Antigen:
MAPRE3
Classification:
Monoclonal
Concentration:
∽1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols:
MAPRE3
Immunogen:
Clone KT53 was generated from a GST fusion protein containing human EB3. This sequence is highly conserved in rat and mouse EB3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
KT53
Conjugate:
Unconjugated
Gene:
MAPRE3
Gene Alias:
AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100732, 22924, 298848
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a
Antigen: Fascin
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P85845, Q16658, Q61553
Gene Symbols: FSCN1
Immunogen: Clone (55K2) was generated from full-length human fascin purified from HeLa cells. This sequence has high homology to rat and mouse fascin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: 55K2
Conjugate: Unconjugated
Gene: FSCN1
Gene Alias: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; AI663989; Fan1; fascin; fascin 1; fascin actin-bundling protein 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus); fascin homolog 1, actin-bundling protein; Fascin1; fascin-1; Fscn1; fscn1 {ECO:0000250; HSN; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; SNL; UniProtKB:Q16658}
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14086, 6624, 683788
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Fascin
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P85845, Q16658, Q61553
Gene Symbols:
FSCN1
Immunogen:
Clone (55K2) was generated from full-length human fascin purified from HeLa cells. This sequence has high homology to rat and mouse fascin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
55K2
Conjugate:
Unconjugated
Gene:
FSCN1
Gene Alias:
55 kDa actin-bundling protein; 55kDa actin-bundling protein; AI663989; Fan1; fascin; fascin 1; fascin actin-bundling protein 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus); fascin homolog 1, actin-bundling protein; Fascin1; fascin-1; Fscn1; fscn1 {ECO:0000250; HSN; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; SNL; UniProtKB:Q16658}
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14086, 6624, 683788
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: FHOD1
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q9Y613
Gene Symbols: FHOD1
Immunogen: FHOD1 recombinant protein that included the full length human FHOD1 sequence. This sequence has 50% homology to human FHOD3, and low homology to other formin family members.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Frozen), Western Blot
Clone: M352
Conjugate: Unconjugated
Gene: FHOD1
Gene Alias: BC017144; FH1/FH2 domain-containing protein 1; Fhod1; FHOS; FHOS1; formin homolog overexpressed in spleen 1; formin homology 2 domain containing 1; formin homology 2 domain-containing protein 1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 29109
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
FHOD1
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q9Y613
Gene Symbols:
FHOD1
Immunogen:
FHOD1 recombinant protein that included the full length human FHOD1 sequence. This sequence has 50% homology to human FHOD3, and low homology to other formin family members.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Western Blot
Clone:
M352
Conjugate:
Unconjugated
Gene:
FHOD1
Gene Alias:
BC017144; FH1/FH2 domain-containing protein 1; Fhod1; FHOS; FHOS1; formin homolog overexpressed in spleen 1; formin homology 2 domain containing 1; formin homology 2 domain-containing protein 1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
29109
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1