PIMA547722

Laminin beta-2/gamma-1 Monoclonal Antibody (M046), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547722-Each-of-1 In Stock ₹ 44,961.78

PIMA547722 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Laminin beta-2/gamma-1

Classification

Monoclonal

Concentration

∽1.0 mg/mL

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P11047, P55268

Gene Symbols

LAMB2, LAMC1

Immunogen

Clone (M046) was generated from a recombinant human laminin 521 protein that includes a heterotrimer of three subunits laminin alpha5, laminin beta2, and laminin gamma1 subunits.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

M046

Conjugate

Unconjugated

Gene

LAMB2

Gene Alias

AA408497; AW211941; B2e; basement membrane protein; Lama; Lamb2; Lamb-2; Lamc1; Laminin B1s chain; laminin B2 chain; laminin beta 2; laminin beta 2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1 chain; Laminin S; laminin subunit beta 2; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma-1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1; laminin, gamma 1 (formerly LAMB2); laminin-1 subunit gamma; Laminin-10 subunit gamma; laminin-11 subunit beta; Laminin-11 subunit gamma; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit gamma; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; Laminin-6 subunit gamma; laminin-7 subunit beta; Laminin-7 subunit gamma; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMS; NPHS5; npht; SLAM; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3913, 3915

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG2b

Description

  • Clone M046 detects native laminin isoforms that include both laminin beta2 and gamma1 subunits
  • In native immunoblots, the antibody detects laminin 521, laminin 221, and laminin 121, but does not detect lamin 332 and laminin 411
  • The antibody weakly detects laminin 511
  • This antibody can be used for immunocytochemical detection of laminin beta2/gamma1 subunits, and can also be used for detection of native laminin isoforms in immunoblots and ELISA
  • Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains
  • They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM
  • Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.

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Img

Thermo Scientific

PIMA547722

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Antigen:
Laminin beta-2/gamma-1

Classification:
Monoclonal

Concentration:
∽1.0 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P11047, P55268

Gene Symbols:
LAMB2, LAMC1

Immunogen:
Clone (M046) was generated from a recombinant human laminin 521 protein that includes a heterotrimer of three subunits laminin alpha5, laminin beta2, and laminin gamma1 subunits.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
M046

Conjugate:
Unconjugated

Gene:
LAMB2

Gene Alias:
AA408497; AW211941; B2e; basement membrane protein; Lama; Lamb2; Lamb-2; Lamc1; Laminin B1s chain; laminin B2 chain; laminin beta 2; laminin beta 2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1 chain; Laminin S; laminin subunit beta 2; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma-1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1; laminin, gamma 1 (formerly LAMB2); laminin-1 subunit gamma; Laminin-10 subunit gamma; laminin-11 subunit beta; Laminin-11 subunit gamma; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit gamma; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; Laminin-6 subunit gamma; laminin-7 subunit beta; Laminin-7 subunit gamma; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMS; NPHS5; npht; SLAM; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3913, 3915

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG2b

Img

Thermo Scientific

PIMA547723

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Antigen:
MURF1

Classification:
Monoclonal

Concentration:
∽2.0 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q38HM4, Q91Z63, Q969Q1

Gene Symbols:
TRIM63

Immunogen:
Clone M316 was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal half of human MuRF1. This peptide sequence is highly conserved in rat and mouse MuRF1, and has 50% homology to MuRF2 (TRIM-55).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M316

Conjugate:
Unconjugated

Gene:
TRIM63

Gene Alias:
E3 ubiquitin-protein ligase TRIM63; FLJ32380; IRF; iris ring finger protein; Murf; MURF 1; MuRF1; MuRF-1; MURF2; muscle ring finger protein 1; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; OTTHUMP00000008701; RF1; ring finger protein 28; RING-type E3 ubiquitin transferase TRIM63; RNF 28; RNF28; SMRZ; striated muscle RING zinc finger protein; TRIM 63; Trim63; tripartite motif containing 63; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif protein 63; tripartite motif-containing 63; tripartite motif-containing protein 63

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
140939, 433766, 84676

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547724

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Antigen:
Neuropilin 1

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
O14786, P97333, Q9QWJ9

Gene Symbols:
NRP1

Immunogen:
Clone M534 was generated from a neuropilin-1 synthetic peptide (coupled to carrier protein) corresponding to amino acids within the a1 CUB domain of human neuropilin-1. This sequence is highly conserved in rat and mouse neuropilin-1, and has low homology to neuropilin-2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
M534

Conjugate:
Unconjugated

Gene:
NRP1

Gene Alias:
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18186, 246331, 8829

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547728

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Antigen:
PrP

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
F7VJQ1, P04156

Gene Symbols:
PRNP

Immunogen:
Clone (3F4) was generated from a synthetic peptide taken from amino acids in the central region of human prion protein. This sequence is conserved in feline and hamster, but is less conserved in rat and mouse Prion protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Western Blot

Clone:
3F4

Conjugate:
Unconjugated

Gene:
PRNP

Gene Alias:
AA960666; AI325101; Alternative prion protein; alternative prion protein; major prion protein; AltPrP; ASCR; BSE; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; major prion protein; alternative prion protein; major scrapie-associated fibril protein 1; MGC26679; p27-30; PK resistant core; prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein precursor; prion protein precursor PrP; prion protein PrP; prion protein variant a; prion protein variant b; prion protein, PrP; prion protein, structural; prion-related protein; PRIP; Prn; Prn-i; Prnp; Prn-p; PrP; PrP<C>; PrP27-30; PrP33-35C; PrPc; PrPSc; Sinc; SIP; TSE

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5621

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG2a