PIMA547739

Syntaphilin Monoclonal Antibody (M371), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547739-Each-of-1 In Stock ₹ 39,272.04

PIMA547739 - Each of 1

₹ 39,272.04

In Stock

Quantity

1

Base Price: ₹ 39,272.04

GST (18%): ₹ 7,068.967

Total Price: ₹ 46,341.007

Antigen

Syntaphilin

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

B5DF41, O15079, Q80U23

Gene Symbols

SNPH

Immunogen

Clone M371 was generated from a sequence corresponding to amino acids in the N-terminal region of human syntaphilin. This sequence has high homology to mouse and rat syntaphilin.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Western Blot

Clone

M371

Conjugate

Unconjugated

Gene

SNPH

Gene Alias

6430515A01; AW045671; AW556958; AW743098; bA314N13.5; KIAA0374; mKIAA0374; Snph; Syntaphilin

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

241727, 296267, 9751

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

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Description

  • This antibody detects a 70 kDa* protein corresponding to the molecular mass of Syntaphilin on SDS-PAGE immunoblots of adult mouse brain
  • Syntaphilin was initially identified in a yeast two-hybrid screen with the carboxy terminal region of Syntaxin-1 as bait
  • Syntaxin-1 is a key component of the synaptic vesicle docking machinery that forms the SNARE complex with synaptobrevin and SNAP-25
  • Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits the formation of the SNARE complex, thereby potentially regulating synaptic vesicle exocytosis
  • Syntaphilin also binds dynamin-1 and inhibits dynamin-dependent endocytosis
  • Mice lacking syntaphilin show an increased level of mitochondrial motility and a reduced density of axonal mitochondria
  • This correlates with an enhanced short-term facilitation and significant impairments in motor ability, suggesting syntaphilin plays a major role in presynaptic function
  • Multiple isoforms are known to exist.

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Img

Thermo Scientific

PIMA547739

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Antigen:
Syntaphilin

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
B5DF41, O15079, Q80U23

Gene Symbols:
SNPH

Immunogen:
Clone M371 was generated from a sequence corresponding to amino acids in the N-terminal region of human syntaphilin. This sequence has high homology to mouse and rat syntaphilin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M371

Conjugate:
Unconjugated

Gene:
SNPH

Gene Alias:
6430515A01; AW045671; AW556958; AW743098; bA314N13.5; KIAA0374; mKIAA0374; Snph; Syntaphilin

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
241727, 296267, 9751

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547741

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Antigen:
TRPM7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q923J1, Q925B3, Q96QT4

Gene Symbols:
Trpm7

Immunogen:
Clone M573 was generated from TRPM7 synthetic peptide (coupled to carrier) corresponding to amino acids in the extracellular region of human TRPM7. This site is well conserved in rat and mouse TRPM7, but has low homology to other TRPM family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M573

Conjugate:
Unconjugated

Gene:
Trpm7

Gene Alias:
2310022G15Rik; 4833414K03Rik; 5033407O22Rik; ALSPDC; CHAK; CHAK1; Channel kinase 1; Channel-kinase 1; FLJ20117; long transient receptor potential channel 7; long transient receptor potential channel 7 {ECO:0000250; Ltpr7; LTRPC ion channel family member 7; LTRPC7; LTrpC-7; LTrpC7 {ECO:0000250; PubMed:11161216}; RGD:620053}; tr; transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel subfamily M member 7 {ECO:0000312; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential M7; transient receptor potential-phospholipase C-interacting kinase; transient receptor potential-phospholipase C-interacting kinase {ECO:0000303; transient receptor potential-related protein, ChaK; TRMP7; TRP PLIK; Trpm7; trpm7 {ECO:0000312; TRPPLIK; Trp-plik; TRP-PLIK {ECO:0000303; UniProtKB:Q96QT4}

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54822, 58800, 679906

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547742

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Antigen:
TRPM8

Classification:
Monoclonal

Concentration:
∽0.75 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q7Z2W7, Q8R455, Q8R4D5

Gene Symbols:
TRPM8

Immunogen:
Clone M572 was generated from TRPM8 synthetic peptide (coupled to carrier) corresponding to amino acids in the extracellular region of human TRPM8. This site is well conserved in rat and mouse TRPM8, but has low homology to other TRPM family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
M572

Conjugate:
Unconjugated

Gene:
TRPM8

Gene Alias:
CMR1; Cold menthol receptor 1; cold/menthol receptor 1; long transient receptor potential channel 6; LTRPC6; LTrpC-6; MGC2849; short form of the TRPM8 cationic channel; transient receptor melastatin 8 variant 1; transient receptor melastatin 8 variant 2; transient receptor potential cation channel subfamily M member 8; transient receptor potential cation channel, subfamily M, member 8; transient receptor potential p8; transient receptor potential subfamily M member 8; transient receptor potential-p8; TRP ion channel TRPM8; Trpm8; Trpp8; trp-p8

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171382, 171384, 79054

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547743

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Antigen:
c-Myc Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
A synthetic peptide corresponding to aa 408-439 from C-terminus of human c-myc.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
9E10

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; MYC proto-oncogene, bHLH transcription factor; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ