PIMA547791

INSR alpha Chimeric Recombinant Rabbit Monoclonal Antibody (83-14), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547791-Each-of-1 In Stock ₹ 44,961.78

PIMA547791 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

INSR alpha Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P06213

Gene Symbols

INSR

Immunogen

This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Ovine, Porcine

Form

Liquid

Target Molecule

Tag

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone

83-14

Conjugate

Unconjugated

Gene

INSR

Gene Alias

4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3643, 396755, 408017, 443431

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

Description

  • Specificity: Recognises the extracellular domain of the Insulin Receptor alpha
  • Amino acids 469-592 (exon 7 and 8) of Insulin Receptor alpha
  • Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades
  • The insulin receptor
  • Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins
  • These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor
  • Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation
  • Both these signaling cascades are also important for the development of cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA547791

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Antigen:
INSR alpha Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Ovine, Porcine

Form:
Liquid

Target Molecule:
Tag

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone:
83-14

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3643, 396755, 408017, 443431

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA547793

--


Antigen:
INSR alpha Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
Epitope within amino acids 140-301 (the cysteine rich region) of the extracellular domain of the human Insulin Receptor alpha.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Target Molecule:
__

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
83-7

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA547794

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Antigen:
IL-18

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
Q14116

Gene Symbols:
IL18

Immunogen:
Fusion of splenocytes from mice immunized with human IL-18, with SP2/O mouse myeloma cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Target Molecule:
__

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Neutralization

Clone:
125-2H

Conjugate:
Unconjugated

Gene:
IL18

Gene Alias:
cytokine; iboctadekin; IFN-gamma-inducing factor; IGIF; il 18; IL-1 gamma; IL18; IL-18; IL1F4; IL-1g; ILN; interferon gamma inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Interleukin; interleukin 18; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; Interleukin18; Interleukin-18; interleukin-18 proprotein; interleukin-18-like protein; MGC12320

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3606

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA547797

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Antigen:
P-Glycoprotein Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P08183

Gene Symbols:
ABCB1

Immunogen:
Drug resistant K-562 cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Target Molecule:
__

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation

Clone:
MRK16

Conjugate:
Unconjugated

Gene:
ABCB1

Gene Alias:
ABC superfamily; P-glycoprotein; ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; ATP binding cassette subfamily B member 1; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette sub-family B member 1; ATP-binding cassette sub-family B member 1A; ATP-binding cassette sub-family B member 1B; ATP-binding cassette transporter subfamily B, member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, subfamily B (MDR/TAP), member 1A; ATP-binding cassette, sub-family B (MDR/TAP), member 1A; ATP-binding cassette, subfamily B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, subfamily B, member 1A; ATP-binding cassette, subfamily B, member 1B; ATP-dependent translocase ABCB1; ATP-dependent translocase ABCB1; multidrug r

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5243

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ