PIMA547836

Basiliximab Chimeric Recombinant Rabbit Monoclonal Antibody (Basiliximab), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547836-Each-of-1 In Stock ₹ 44,961.78

PIMA547836 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Basiliximab Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Cynomolgus Monkey, Human, Rhesus Monkey

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Inhibition Assays, Western Blot

Clone

Basiliximab

Conjugate

Unconjugated

Gene Alias

CHI621

Immunogen

Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.

Quantity

200 μg

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • Specificity: Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit-binding is abolished when 2 or more residues within the epitope are mutated
  • This epitope overlaps with the interaction site of CD25 and IL-2
  • CD25 is found in the high-affinity IL-2R (alpha-Beta-gamma-c)-T cells only express CD25 upon activation
  • IL-2 binding to IL-2R on T cells modulates proliferation and differentiation
  • A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes
  • It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha
  • Basiliximab binds with high-affinity to the alpha-subunit (CD25) of the high-affinity IL-2 receptor
  • This inhibits IL-2 binding, which inhibits T-cell activation and prevents the body from mounting an immune response against the foreign kidney.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA547836

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Antigen:
Basiliximab Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Cynomolgus Monkey, Human, Rhesus Monkey

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Inhibition Assays, Western Blot

Clone:
Basiliximab

Conjugate:
Unconjugated

Gene Alias:
CHI621

Immunogen:
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA547837

--


Antigen:
AFP

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
AF5

Conjugate:
Unconjugated

Gene Alias:
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein

Immunogen:
AF5 was prepared by immunizing female BALB/c mice with human amniotic fluid containing AFP, from a pregnancy affected by a neural tube defect, diluted and emulsified in Freund's complete adjuvant.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA547838

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Antigen:
AFP Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
AF5

Conjugate:
Unconjugated

Gene Alias:
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein

Immunogen:
AF5 was prepared by immunizing female BALB/c mice with human amniotic fluid containing AFP, from a pregnancy affected by a neural tube defect, diluted and emulsified in Freund's complete adjuvant.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA547839

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Antigen:
CD19

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Inhibition Assays

Clone:
HD37

Conjugate:
Unconjugated

Gene Alias:
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

Immunogen:
Cells from a hairy cell leukemia patient.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ