PIMA547989

TCR V alpha 11 Chimeric Recombinant Mouse Monoclonal Antibody (34), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547989-Each-of-1 In Stock ₹ 44,961.78

PIMA547989 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

TCR V alpha 11 Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P01854

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3497

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

Applications

ELISA, Flow Cytometry, Western Blot

Clone

34

Conjugate

Unconjugated

Gene

IGHE

Gene Alias

TCR V alpha11; TCRV alpha 11; TCRV alpha11; Va11; Valpha11

Immunogen

Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Specificity: This antibody binds to the T-cell receptor alpha chains
  • The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
  • TCR recognition of self-peptides has been linked to autoimmune disease
  • Mutant self-peptides have been associated with tumors
  • Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
  • Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
  • The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease
  • Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
  • A small number of T cells lack both CD4 and CD8 (double negative, DN)
  • Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
  • Gamma-delta T cells are primarily found within the epithelium
  • They show less TCR diversity and recognize antigens differently than alpha-beta T cells
  • Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA547989

--


Antigen:
TCR V alpha 11 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P01854

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3497

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
34

Conjugate:
Unconjugated

Gene:
IGHE

Gene Alias:
TCR V alpha11; TCRV alpha 11; TCRV alpha11; Va11; Valpha11

Immunogen:
Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIMA547990

--


Antigen:
TCR V alpha 11 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
Q05685

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14276

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
34

Conjugate:
Unconjugated

Gene:
FOLR2

Gene Alias:
TCR V alpha11; TCRV alpha 11; TCRV alpha11; Va11; Valpha11

Immunogen:
Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIMA547991

--


Antigen:
CD41/CD61 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P05106, P08514

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3674, 3690

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
10E5

Conjugate:
Unconjugated

Gene:
ITGA2B

Gene Alias:
alphaIIb protein, antigen CD61, BDPLT16, BDPLT2, CD41, CD41B, CD61, glycoprotein GPIIb, glycoprotein GPIIIa, glycoprotein IIb, glycoprotein IIIa, GP2B, GP3A, GPalpha IIb, GPIIb, GPIIIa, GT, GTA, HPA3, INTB3, integrin, integrin alpha 2b, integrin alpha 2b precursor, Integrin alpha-2b, integrin alpha-IIb, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2, Integrin beta, integrin beta 3, integrin beta 3 subunit, integrin beta3, integrin beta-3, integrin beta-3 subunit, integrin subunit alpha 2b, integrin subunit alpha IIb, integrin subunit beta 3, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B), integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITGA2B, ITGA2B-like protein, ITGAB, ITGB3, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb, platelet glycoprotein IIb of IIb/IIIa complex, platelet glycoprotein IIIa, platelet glycoprotein IIIa integrin subunit beta 3, platelet membrane glycoprotein IIb, Platelet membrane glycoprotein IIIa, platelet-specific antigen BAK, PPP1R93, protein phosphatase 1, regulatory subunit 93

Immunogen:
Human blood platelets.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIMA547993

--


Antigen:
CD147

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P35613

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
682

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Applications:
ELISA, Immunocytochemistry, Inhibition Assays

Clone:
Ab-1

Conjugate:
Unconjugated

Gene:
BSG

Gene Alias:
5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383

Immunogen:
Recombinant ectodomains of human basigin.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid