PIMA548077
FIBB Recombinant Mouse Monoclonal Antibody (8E5), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA548077-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA548077 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
FIBB
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
P02675
Gene Symbols
Fgb
Immunogen
8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Functional Assay, Immunomicroscopy
Clone
8E5
Conjugate
Unconjugated
Gene
Fgb
Gene Alias
2510049G14Rik; Ab1-181; Ab1-216; Ac1-581; B beta polypeptide; beta-fibrinogen; epididymis secretory sperm binding protein Li 78p; Fgb; fibrinogen; Fibrinogen beta chain; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; Fibrinopeptide B; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC104327; MGC120405
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2244
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- Specificity: 8E5 binds to the amino-terminal region of the Beta-chain of human fibrin at an epitope consiting of GHRPLDKC
- Binding is possible in both the monomeric form and the polymeric form of the protein
- The epitope recognised by this clone is only accessible upon conversion of fibrinogen to fibrin, which entails the proteolytic removal of fibrinopeptides A & B from fibrinogen by thrombin
- The antibody is there is therefore fibrin specific
- Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen
- Polymerization occurs through the action of the protease thrombin, which results in the active fibrin
- Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site
- FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains
- Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots
- In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types
- Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
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Antigen: FIBB
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P02675
Gene Symbols: Fgb
Immunogen: 8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Functional Assay, Immunomicroscopy
Clone: 8E5
Conjugate: Unconjugated
Gene: Fgb
Gene Alias: 2510049G14Rik; Ab1-181; Ab1-216; Ac1-581; B beta polypeptide; beta-fibrinogen; epididymis secretory sperm binding protein Li 78p; Fgb; fibrinogen; Fibrinogen beta chain; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; Fibrinopeptide B; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC104327; MGC120405
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2244
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
FIBB
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P02675
Gene Symbols:
Fgb
Immunogen:
8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Functional Assay, Immunomicroscopy
Clone:
8E5
Conjugate:
Unconjugated
Gene:
Fgb
Gene Alias:
2510049G14Rik; Ab1-181; Ab1-216; Ac1-581; B beta polypeptide; beta-fibrinogen; epididymis secretory sperm binding protein Li 78p; Fgb; fibrinogen; Fibrinogen beta chain; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; Fibrinopeptide B; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC104327; MGC120405
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2244
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: FAS (CD95)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P25445
Gene Symbols: FAS
Immunogen: Partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423).
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunomicroscopy, T-Cell Activation
Clone: R-125224
Conjugate: Unconjugated
Gene: FAS
Gene Alias: AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 355
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
FAS (CD95)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P25445
Gene Symbols:
FAS
Immunogen:
Partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423).
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunomicroscopy, T-Cell Activation
Clone:
R-125224
Conjugate:
Unconjugated
Gene:
FAS
Gene Alias:
AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
355
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: CD154 (CD40 Ligand) Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P29965
Gene Symbols: CD40LG
Immunogen: Proprietary sequence.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: YMF323.6
Conjugate: Unconjugated
Gene: CD40LG
Gene Alias: CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 959
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
CD154 (CD40 Ligand) Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P29965
Gene Symbols:
CD40LG
Immunogen:
Proprietary sequence.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
YMF323.6
Conjugate:
Unconjugated
Gene:
CD40LG
Gene Alias:
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
959
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: CD154 (CD40 Ligand)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P29965
Gene Symbols: CD40LG
Immunogen: Proprietary sequence.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: YMF323.6
Conjugate: Unconjugated
Gene: CD40LG
Gene Alias: CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Host Species: Rat
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 959
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a κ
Antigen:
CD154 (CD40 Ligand)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P29965
Gene Symbols:
CD40LG
Immunogen:
Proprietary sequence.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
YMF323.6
Conjugate:
Unconjugated
Gene:
CD40LG
Gene Alias:
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Host Species:
Rat
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
959
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a κ