PIMA548106

CTLA-4 (CD152) Chimeric Recombinant Rabbit Monoclonal Antibody (9H10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548106-Each-of-1 In Stock ₹ 44,961.78

PIMA548106 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

CTLA-4 (CD152) Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P09793

Gene Symbols

CTLA4

Immunogen

This antibody was raised by immunising Syrian hamsters with Staphylococcus A bacteria coated in CTLA-4, isolating B cells from the immunised hamsters and fusing these with the P3X3.Ag8.653 myeloma line to produce stable hybridomas.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

ELISA, Flow Cytometry, Neutralization, Western Blot

Clone

9H10

Conjugate

Unconjugated

Gene

CTLA4

Gene Alias

ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12477

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

Related Products

Img

Thermo Scientific

PIMA548216

--

Img

Thermo Scientific

PIMA548196

--

Img

Thermo Scientific

PIMA548131

--

Img

Thermo Scientific

PIMA548318

--

Img

Thermo Scientific

PIMA548274

--

Img

Thermo Scientific

PIMA548137

--

Img

Thermo Scientific

PIMA548090

--

Img

Thermo Scientific

PIMA548238

--

Description

  • Specificity: This antibody is specific for murine CTLA-4, an inhibitory receptor that acts as the primary negative regulator of T-cell responses
  • CTLA-4 is expressed predominantly by activated T cells, with significantly higher levels of expression on CD8+ T cells than CD4+ T cells
  • CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells
  • It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28
  • However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning
  • Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA548106

--


Antigen:
CTLA-4 (CD152) Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P09793

Gene Symbols:
CTLA4

Immunogen:
This antibody was raised by immunising Syrian hamsters with Staphylococcus A bacteria coated in CTLA-4, isolating B cells from the immunised hamsters and fusing these with the P3X3.Ag8.653 myeloma line to produce stable hybridomas.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Neutralization, Western Blot

Clone:
9H10

Conjugate:
Unconjugated

Gene:
CTLA4

Gene Alias:
ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12477

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548108

--


Antigen:
CD27

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P41272

Gene Symbols:
CD27

Immunogen:
This antibody was raised by immunising mouse with mouse CD27-human IgG1 Fc fusion protein. Isolated popliteal lymph node cells were then fused with P3U1 myeloma cells to produce stable hybridomas.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunoprecipitation, Neutralization

Clone:
RM27-3E5

Conjugate:
Unconjugated

Gene:
CD27

Gene Alias:
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21940

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a κ

Img

Thermo Scientific

PIMA548109

--


Antigen:
CD35

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P17927

Gene Symbols:
CR1

Immunogen:
Animals were immunized with purified CR1 from human erythrocytes. Spleen cells were fused with P3X63Ag8.653 myeloma cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HB-8592

Conjugate:
Unconjugated

Gene:
CR1

Gene Alias:
C3 binding protein; C3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); Complement Component (3b/4b) receptor 1 including Knops blood group system; complement component 3b/4b receptor 1 (Knops blood group); complement receptor type 1; CR1; KN; Knops blood group antigen

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1378

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA548110

--


Antigen:
CD35 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P17927

Gene Symbols:
CR1

Immunogen:
Animals were immunized with purified CR1 from human erythrocytes. Spleen cells were fused with P3X63Ag8.653 myeloma cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
HB-8592

Conjugate:
Unconjugated

Gene:
CR1

Gene Alias:
C3 binding protein; C3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); Complement Component (3b/4b) receptor 1 including Knops blood group system; complement component 3b/4b receptor 1 (Knops blood group); complement receptor type 1; CR1; KN; Knops blood group antigen

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1378

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ