PIMA548118

Hemoglobin Chimeric Recombinant Rabbit Monoclonal Antibody (2A1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548118-Each-of-1 In Stock ₹ 44,961.78

PIMA548118 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Hemoglobin Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P01942

Gene Symbols

HBA, HBB

Immunogen

Murine hybridomas were generated using spleen cells from aging (8-10 month old) NZB/W F1 animals.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

2A1

Conjugate

Unconjugated

Gene

HBB

Gene Alias

alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; ALPHA-GLOBIN GENE; delta globin; Haemoglobin; Hb; HBA1; HbA1c; HBA2; HBA-T3; HBH; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin, alpha 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15121, 15127

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • Specificity: 2A1 exhibited polyreactive recognition of peptide 100-119 from the alpha subunit and peptide 100-119 frmo the beta subunit
  • Moreover, 2A1 bound Hb and the Hb-haptoglobin complex with equal efficiency, implying different binding sites on Hb for haptoglobin and 2A1
  • 2A1 was also found to distinguish between Hb and metHb
  • Preparation: Murine hybridomas were generated using spleen cells from aging (8-10 month old) NZB/W F1 animals
  • Hybridomas secreting antibodies reactive to murine hemoglobin were subcloned by limiting dilution and antibody isotypes determined using commercial reagents
  • Eight-week-old NZB/W F1 were immunized subcutaneously with 50 mg mHb antigen emulsified in Complete Fruends Adjuvant
  • The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'
  • The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical
  • These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions
  • Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin
  • Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA548118

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Antigen:
Hemoglobin Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P01942

Gene Symbols:
HBA, HBB

Immunogen:
Murine hybridomas were generated using spleen cells from aging (8-10 month old) NZB/W F1 animals.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
2A1

Conjugate:
Unconjugated

Gene:
HBB

Gene Alias:
alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; ALPHA-GLOBIN GENE; delta globin; Haemoglobin; Hb; HBA1; HbA1c; HBA2; HBA-T3; HBH; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin, alpha 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15121, 15127

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548119

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Antigen:
CSF2RB Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P32927

Gene Symbols:
Csf2rb

Immunogen:
BALB/c mice were immunized intraperitonally with COS cells transfected DQP (Domain 4 of the common beta-chain) expression constructs.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Functional Assay, Immunohistochemistry, Immunoprecipitation, In vitro Assay, Inhibition Assays

Clone:
BION-1

Conjugate:
Unconjugated

Gene:
Csf2rb

Gene Alias:
Ai2ca; AI848964; AIC2A; Aic2b; Bc; beta c; beta common cytokine receptor; BetaIl3; Bil3; CD antigen CD131; CD131; CD131 antigen; CDw131; colony stimulating factor 2 receptor beta common subunit; colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); colony-stimulating factor 2 receptor subunit beta-2; colony-stimulating factor-2 receptor, beta, low-affinity; common beta chain; CSF2RB; Csf2rb1; Csf2rb2; Csfgmrb; cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL-3 receptor class 2 subunit beta; Il3r; IL3R beta; IL-3R class 2 subunit beta; IL3RB; Il3rb1; Il3rb2; IL5RB; interleukin 3 common beta chain; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); interleukin-3 receptor class 2 subunit beta; Interleukin-3 receptor class II beta chain; SMDP5

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1439

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA548120

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Antigen:
CSF2RB Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P32927

Gene Symbols:
Csf2rb

Immunogen:
BALB/c mice were immunized intraperitonally with COS cells transfected DQP (Domain 4 of the common beta-chain) expression constructs.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone:
BION-1

Conjugate:
Unconjugated

Gene:
Csf2rb

Gene Alias:
Ai2ca; AI848964; AIC2A; Aic2b; Bc; beta c; beta common cytokine receptor; BetaIl3; Bil3; CD antigen CD131; CD131; CD131 antigen; CDw131; colony stimulating factor 2 receptor beta common subunit; colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); colony-stimulating factor 2 receptor subunit beta-2; colony-stimulating factor-2 receptor, beta, low-affinity; common beta chain; CSF2RB; Csf2rb1; Csf2rb2; Csfgmrb; cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL-3 receptor class 2 subunit beta; Il3r; IL3R beta; IL-3R class 2 subunit beta; IL3RB; Il3rb1; Il3rb2; IL5RB; interleukin 3 common beta chain; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); interleukin-3 receptor class 2 subunit beta; Interleukin-3 receptor class II beta chain; SMDP5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1439

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548124

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Antigen:
TRAIL-R2 (DR5)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
O14763

Gene Symbols:
TNFRSF10B

Immunogen:
The antibody was raised by immunizing BALB/c mice with a fusion protein containing the extracellular portion of human DR5 and the Fc portion of human IgG1.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Functional Assay, Western Blot

Clone:
TRA-8

Conjugate:
Unconjugated

Gene:
TNFRSF10B

Gene Alias:
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8795

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ