PIMA548145

CMKLR1 Chimeric Recombinant Rabbit Monoclonal Antibody (BZ194), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548145-Each-of-1 In Stock ₹ 44,961.78

PIMA548145 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

CMKLR1 Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P97468

Gene Symbols

CMKLR1

Immunogen

This antibody was raised by immunising Wistar Furth rats with the mCMKLR1 peptide (aa 8-32) /KLH conjugate.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry

Clone

BZ194

Conjugate

Unconjugated

Gene

CMKLR1

Gene Alias

chemerin chemokine-like receptor 1; chemerin receptor; CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; CHEMR23; CMKLR1; Dez; Gpcr27; G-protein coupled chemoattractant-like receptor; G-protein coupled receptor 27; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; mcmklr1; orphan G-protein coupled receptor, Dez; resolvin E1 receptor; RVER1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14747

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • Specificity: This antibody is specific for murine serpentine receptor mCMKLR1 (aka ChemR23, DEZ)
  • mCMKLR1 is a novel protein possessing high homology with members of the chemoattractant receptor family, and binds the chemoattractant chemerin
  • Selective mCMKLR1 expression has been demonstrated by mouse macrophages ex vivo, and by dendritic cell precursors cultured in vitro
  • Preparation: This antibody was raised by immunising Wistar Furth rats with the mCMKLR1 peptide/KLH conjugate
  • The immunizing amino-terminal mCMKLR1 peptide with the sequence NH2-DSGIYDDEYSDGFGYFVDLEEASPWC-COOH, corresponding to residues residues 8-32 of mCMKLR1, with a nonnative carboxyl-terminal cysteine to facilitate conjugation to keyhole limpet hemocyanin (KLH)
  • Chemokine-like receptor 1 (CMKLR1) is a receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1
  • Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis
  • Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B
  • CMKLR1 positively regulates adipogenesis and adipocyte metabolism and acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA548145

--


Antigen:
CMKLR1 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P97468

Gene Symbols:
CMKLR1

Immunogen:
This antibody was raised by immunising Wistar Furth rats with the mCMKLR1 peptide (aa 8-32) /KLH conjugate.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry

Clone:
BZ194

Conjugate:
Unconjugated

Gene:
CMKLR1

Gene Alias:
chemerin chemokine-like receptor 1; chemerin receptor; CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; CHEMR23; CMKLR1; Dez; Gpcr27; G-protein coupled chemoattractant-like receptor; G-protein coupled receptor 27; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; mcmklr1; orphan G-protein coupled receptor, Dez; resolvin E1 receptor; RVER1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14747

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

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PIMA548147

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Antigen:
CD137 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P20334

Gene Symbols:
TNFRSF9

Immunogen:
This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, T-Cell Activation

Clone:
LOB12.3

Conjugate:
Unconjugated

Gene:
TNFRSF9

Gene Alias:
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21942

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

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PIMA548148

--


Antigen:
CD137 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P20334

Gene Symbols:
TNFRSF9

Immunogen:
This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, T-Cell Activation

Clone:
LOB12.3

Conjugate:
Unconjugated

Gene:
TNFRSF9

Gene Alias:
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21942

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a κ

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PIMA548149

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Antigen:
TL1A Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
Q5UBV8

Gene Symbols:
TNFSF15

Immunogen:
This antibody was raised by immunising rats with a soluble recombinant TL1A (T77-L252):Fc protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Inhibition Assays

Clone:
TAN2-2

Conjugate:
Unconjugated

Gene:
TNFSF15

Gene Alias:
bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15); MGC129934; MGC129935; TL1; TL1A; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; TNFSF15; TNLG1B; tumor necrosis factor (ligand) superfamily member 15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand 1B; tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form; tumor necrosis factor superfamily member 15; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor; vascular endothelial growth inhibitor-192A; Vegi; VEGI192A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
326623

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ