PIMA548152

4-1BB Ligand Recombinant Rat Monoclonal Antibody (AT113-2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548152-Each-of-1 In Stock ₹ 44,961.78

PIMA548152 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

4-1BB Ligand

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P41274

Gene Symbols

TNFSF9

Immunogen

This antibody was raised by immunising LOU rats with soluble recombinant 4-1BBL:Fc fusion protein.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

Flow Cytometry, Inhibition Assays, Western Blot

Clone

AT113-2

Conjugate

Unconjugated

Gene

TNFSF9

Gene Alias

4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21950

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Specificity: This antibody is specific for 4-1BB ligand (also known as CD137 ligand), which is a member of the TNF superfamily and is a type II membrane protein
  • CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily
  • CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation
  • Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes
  • Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity
  • CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma)
  • CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA548152

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Antigen:
4-1BB Ligand

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P41274

Gene Symbols:
TNFSF9

Immunogen:
This antibody was raised by immunising LOU rats with soluble recombinant 4-1BBL:Fc fusion protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Inhibition Assays, Western Blot

Clone:
AT113-2

Conjugate:
Unconjugated

Gene:
TNFSF9

Gene Alias:
4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21950

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA548153

--


Antigen:
CD70 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
O55237

Gene Symbols:
Cd70

Immunogen:
This antibody was raised by immunising LOU rats with soluble recombinant CD70:Fc fusion protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Inhibition Assays, Western Blot

Clone:
TAN1-6

Conjugate:
Unconjugated

Gene:
Cd70

Gene Alias:
CD27 ligand; Cd27l; CD27-L; CD27LG; CD70; CD70 antigen; Cd70 molecule; Ki-24 antigen; surface antigen CD70; Tnfsf7; TNLG8A; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21948

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548154

--


Antigen:
CD70

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
O55237

Gene Symbols:
Cd70

Immunogen:
This antibody was raised by immunising LOU rats with soluble recombinant CD70:Fc fusion protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Inhibition Assays, Western Blot

Clone:
TAN1-6

Conjugate:
Unconjugated

Gene:
Cd70

Gene Alias:
CD27 ligand; Cd27l; CD27-L; CD27LG; CD70; CD70 antigen; Cd70 molecule; Ki-24 antigen; surface antigen CD70; Tnfsf7; TNLG8A; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21948

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a κ

Img

Thermo Scientific

PIMA548155

--


Antigen:
TIM-3 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
Q8VIM0

Gene Symbols:
Havcr2

Immunogen:
This antibody was raised by immunising rats with TIM-3:Ig fusion protein emulsified in complete Freunds adjuvant.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry

Clone:
2C12

Conjugate:
Unconjugated

Gene:
Havcr2

Gene Alias:
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
171285

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ