PIMA548168

TIMD2 Recombinant Rat Monoclonal Antibody (RMT2-14), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA548168-Each-of-1 In Stock ₹ 44,961.78

PIMA548168 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

TIMD2

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

Q8R183

Gene Symbols

Timd2

Immunogen

This antibody was raised by immunising Sprague Dawley rats with TIM-2-Ig consisting of the extracellular domain (aa 1-230 of mouse TIM-2) and the Fc portion of mouse IgG2a, emulsified in complete Freund's adjuvant and then fusing lymph node cells from the immunized rats with P3U1 myeloma cells.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry, Inhibition Assays, Western Blot

Clone

RMT2-14

Conjugate

Unconjugated

Gene

Timd2

Gene Alias

AA816106; AU019358; AU019662; C78111; G9D3; T cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin and mucin domain-containing protein 2; T-cell immunoglobulin mucin receptor 2; T-cell membrane protein 2; Tim2; TIM-2; Timd2; TIMD-2

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

171284

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a λ

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Description

  • Specificity: This antibody is specific for murine TIM-2, a transmembrane protein that is expressed on activated T cells and preferentially on differentiated Th2 cells
  • A blockade of TIM-2/TIM-2 ligand interaction results in T cell hyperproliferation and Th2 cytokine production
  • TIM-2 plays a critical role in the development of atopic disease and other Th2-biased immune responses
  • TIM-2 recognizes T-cell immunoglobulin mucin 2, a transmembrane glycoprotein and member of the immunoglobulin superfamily, expressed by activated lymphocytes, developmentally in the 8-cell embryo and blastocyst, and preferentially up-regulated in Th2 cells and down-regulated in Th1 cells
  • Tim-2 acts as a negative regulator of Th2 cells, and is implicated to play a critical role in the development of atopic disease and other Th2-biased immune responses
  • Tim-2 also acts as a receptor for Semaphorin 4A, a transmembrane protein expressed on dendritic cells and B cells, which plays a role in the guidance of axonal migration during neuronal development, and has been shown to enhance T cell activation.

Compare Similar Items

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Img

Thermo Scientific

PIMA548168

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Antigen:
TIMD2

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
Q8R183

Gene Symbols:
Timd2

Immunogen:
This antibody was raised by immunising Sprague Dawley rats with TIM-2-Ig consisting of the extracellular domain (aa 1-230 of mouse TIM-2) and the Fc portion of mouse IgG2a, emulsified in complete Freund's adjuvant and then fusing lymph node cells from the immunized rats with P3U1 myeloma cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry, Inhibition Assays, Western Blot

Clone:
RMT2-14

Conjugate:
Unconjugated

Gene:
Timd2

Gene Alias:
AA816106; AU019358; AU019662; C78111; G9D3; T cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin and mucin domain-containing protein 2; T-cell immunoglobulin mucin receptor 2; T-cell membrane protein 2; Tim2; TIM-2; Timd2; TIMD-2

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171284

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a λ

Img

Thermo Scientific

PIMA548169

--


Antigen:
CD25 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P01590

Gene Symbols:
IL2RA

Immunogen:
This antibody was raised by immunising rats with the B6.1 mouse cytotoxic T cell line, followed by fusing spleen cells with P3X63Ag8.653 myeloma cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot

Clone:
PC-61.5.3

Conjugate:
Unconjugated

Gene:
IL2RA

Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16184

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG λ

Img

Thermo Scientific

PIMA548170

--


Antigen:
CD25 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P01590

Gene Symbols:
IL2RA

Immunogen:
This antibody was raised by immunising rats with the B6.1 mouse cytotoxic T cell line, followed by fusing spleen cells with P3X63Ag8.653 myeloma cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot

Clone:
PC-61.5.3

Conjugate:
Unconjugated

Gene:
IL2RA

Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16184

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a λ

Img

Thermo Scientific

PIMA548171

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Antigen:
IFNGR1 (CD119) Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P15261

Gene Symbols:
IFNGR1

Immunogen:
This antibody was raised by immunising rats with interferon gamma receptor.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Inhibition Assays, Neutralization

Clone:
GR20

Conjugate:
Unconjugated

Gene:
IFNGR1

Gene Alias:
antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; Ifgr; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; IFNGR1; IMD27A; IMD27B; immune interferon receptor 1; INF-g receptor; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain; Nktar

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15979

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ