PIMA548348
CD18 Chimeric Recombinant Rabbit Monoclonal Antibody (60.3), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA548348-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA548348 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
CD18 Chimeric
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
P05107
Gene Symbols
ITGB2
Immunogen
The original antibody was generated by immunizing BALB/c mice with alloantigen activated T cells.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone
60.3
Conjugate
Unconjugated
Gene
ITGB2
Gene Alias
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3689
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG κ
Related Products
Description
- Specificity: This antibody binds the CD18 component of the Beta-2 integrin family which is expressed by leukocytes and neutrophils
- CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes
- CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling
- CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18)
- In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts
- Absence of CD18 leads to leukocyte adhesion deficiency-1, severe reduction of CD18 expression leads to the development of a psoriasiform skin disease
- CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis
- Defects in the CD18 gene are the cause of leukocyte adhesion deficiency type I (LAD1)
- Two transcript variants encoding the CD18 protein have been identified.
Compare Similar Items
Show Difference
Antigen: CD18 Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P05107
Gene Symbols: ITGB2
Immunogen: The original antibody was generated by immunizing BALB/c mice with alloantigen activated T cells.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone: 60.3
Conjugate: Unconjugated
Gene: ITGB2
Gene Alias: 2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3689
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
CD18 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P05107
Gene Symbols:
ITGB2
Immunogen:
The original antibody was generated by immunizing BALB/c mice with alloantigen activated T cells.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone:
60.3
Conjugate:
Unconjugated
Gene:
ITGB2
Gene Alias:
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3689
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: Mesothelin Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: Q13421
Gene Symbols: MSLN
Immunogen: The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone: 11-25
Conjugate: Unconjugated
Gene: MSLN
Gene Alias: CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10232
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
Mesothelin Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
Q13421
Gene Symbols:
MSLN
Immunogen:
The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone:
11-25
Conjugate:
Unconjugated
Gene:
MSLN
Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10232
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: Mesothelin
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: Q13421
Gene Symbols: MSLN
Immunogen: The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA
Clone: IC14-30
Conjugate: Unconjugated
Gene: MSLN
Gene Alias: CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10232
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
Mesothelin
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
Q13421
Gene Symbols:
MSLN
Immunogen:
The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA
Clone:
IC14-30
Conjugate:
Unconjugated
Gene:
MSLN
Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10232
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: CD25 Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P01590
Gene Symbols: IL2RA
Immunogen: The original version of this antibody was raised to recognize mouse CD25.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot
Clone: 2E4
Conjugate: Unconjugated
Gene: IL2RA
Gene Alias: ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16184
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
CD25 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P01590
Gene Symbols:
IL2RA
Immunogen:
The original version of this antibody was raised to recognize mouse CD25.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot
Clone:
2E4
Conjugate:
Unconjugated
Gene:
IL2RA
Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16184
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ